---
title: "Average weight loss on Zepbound: trial results"
description: "Average weight loss on Zepbound in trials was about 15% to 21% at 72 weeks with diet and activity. Your results can vary by dose."
canonical: "https://www.vitalsvault.com/treatment-learn/average-weight-loss-on-zepbound"
last-updated: 2026-08-22
---

# Average weight loss on Zepbound: trial results

> Average weight loss on Zepbound in trials was about 15% to 21% at 72 weeks with diet and activity. Your results can vary by dose.

---

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