Function Health vs Vitals VaultDon't buy your follow-up before you know what needs follow-up.

Function Health is advertised at $365/year. Vitals Vault is one-time: $99 for Essential with 120 reported biomarkers and clinical ratios, $199 for Advanced with 140, or $399 for Max with 160. If you want follow-up testing, another full Essential panel is $99, so three Essential draws are $297 and four are $396. Targeted follow-up biomarkers can start at $14.99. HSA/FSA eligibility can depend on your plan.

Every plan includes a 90-page Functional Health Report that evaluates each biomarker against two sets of ranges: the standard lab range (are you sick?) and a functional optimal range (are you actually healthy?). Here’s the difference that matters: Function Health told you your TSH of 4.0 was “normal.” A functional medicine practitioner knows anything above 3.0 correlates with early thyroid underperformance — and you’ve been blaming the fatigue on sleep. Your fasting glucose of 94 passed their screen. Our TyG Index flags the insulin resistance behind it a decade before your A1c moves. Your ferritin of 25 was “within range.” But paired with your hs-CRP and dropping iron saturation, it’s a pattern of chronic inflammation no standard report would connect. The report scores 12 body systems, computes 34–50 clinical ratios that don’t exist on your Function Health dashboard, and gives you an Action Plan with specific supplement recommendations, dosages, safety notes relative to your medications, and PubMed-cited evidence — not “eat more vegetables.”

Yes — and this is one of the biggest differences. Function Health gives every member the same ~100-biomarker panel regardless of whether you’re a 28-year-old woman with PCOS symptoms or a 55-year-old man on statins with a family history of heart disease. Vitals Vault’s Custom Panel Builder is an AI clinical consultation that conducts a multi-turn interview about your symptoms, medications, family history, and lifestyle — the kind of workup you’d get at a $10,000 concierge medicine practice. It builds differential hypotheses about what’s driving your symptoms (thyroid dysfunction? insulin resistance? chronic inflammation?), then assembles a panel that tests those specific hypotheses. You see exactly why each test was selected, which clinical findings it investigates, and the confidence level for each hypothesis. The system runs deterministic medication-depletion rules (statins → CoQ10, metformin → B12, PPIs → magnesium), family-history risk panels, and then layers an LLM consultation on top. No other blood testing service — not Function Health, not InsideTracker, not Superpower — offers anything like this. They give everyone the same tests. We build yours.

Function Health is an annual testing membership: 100+ lab tests first, then 60+ tests halfway through the year to see what changed. That is an annual count across two testing moments. The 60+ follow-up is not the same as 60 new unique biomarkers, and it is not a custom panel selected because your first results showed a specific issue. If you counted repeat testing the same way, two Vitals Vault Essential panels would be 240 test events for $198. But the clearer comparison is simpler: 120 upfront for $99, then choose whether you need a full retest or only a few targeted markers.

Yes. Vitals Vault is built around a broad Quest-based add-on catalog, so you can go beyond the core panel with targeted testing for specific symptoms, goals, or follow-up questions. Targeted follow-up biomarkers can start at $14.99, with availability and pricing varying by test.

Your report is powered by a clinical intelligence engine built on a 3-million-node knowledge graph (HPO, SNOMED, UMLS, and functional medicine ontologies). It doesn’t just flag individual markers — it detects compound risk patterns the way a functional medicine doctor thinks. For example: elevated LDL + elevated hs-CRP + family history of heart disease triggers a “Cardiac Triple Threat” pattern that exponentially increases your risk beyond what any single number shows. High glucose + high triglycerides + low HDL triggers a “Metabolic Syndrome Pattern.” The engine evaluates your results against your 15-section health profile (medications, family history, symptoms, diet, sleep, stress, supplements, and more), uses UMLS/RxNorm to understand drug interactions with your current medications, and detects worsening trends across past labs. All protocols were developed with Dr. Arti Chandra (MD, MPH, IFMCP — 15 years functional medicine at Providence/Swedish) and Dr. Rob Lufkin (Clinical Professor, USC Keck School of Medicine, 200+ peer-reviewed papers). Every report receives clinician sign-off. This isn’t a chatbot — it’s a physician-designed clinical engine that thinks in constellations, not isolated numbers.