---
title: "Naltrexone weight loss: evidence and safety"
description: "Naltrexone alone is not FDA approved for weight loss. Evidence is limited, and safety depends on your history, especially opioid use and liver disease."
canonical: "https://www.vitalsvault.com/treatment-learn/naltrexone-for-weight-loss"
last-updated: 2026-08-22
---

# Naltrexone weight loss: evidence and safety

> Naltrexone alone is not FDA approved for weight loss. Evidence is limited, and safety depends on your history, especially opioid use and liver disease.

---

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