Vitals Vault Comprehensive Female Hormone Panel
A comprehensive female hormone lab panel measuring estrogen, progesterone, LH/FSH, prolactin, androgens, and thyroid markers to guide next steps.
This panel bundles multiple biomarker tests in one order—your report explains how results fit together.
This is a lab panel, not a single hormone test. In one blood draw, the Vitals Vault Comprehensive Female Hormone Panel looks at multiple hormone systems that often overlap—ovarian hormones, pituitary signaling, and key thyroid markers—so your results can be interpreted as a pattern instead of a single number in isolation.
Because hormones shift across the menstrual cycle (and change during postpartum, perimenopause, and with many medications), the most useful takeaway is usually how your markers fit together for your timing, symptoms, and goals.
Do I need this panel?
You may benefit from this panel if you are trying to connect symptoms to a measurable hormone pattern—especially when symptoms could come from more than one system. Common reasons include irregular or long cycles, acne or unwanted hair growth, scalp hair thinning, new or stubborn weight changes, low libido, mood changes around your cycle, heavy bleeding, or difficulty predicting ovulation.
This panel is also useful if you are tracking PCOS (polycystic ovary syndrome) patterns, navigating perimenopause transitions, or reassessing hormones after starting or stopping hormonal contraception, fertility medications, thyroid medication, or supplements that can affect hormone binding.
You may not need a broad panel if you have a very specific question (for example, confirming pregnancy or checking a single medication level). But when your symptoms span cycle, energy, sleep, and body composition—or when prior “normal” results did not match how you feel—a multi-marker panel can prevent missed context.
This panel supports clinician-directed care and informed conversations; it cannot diagnose conditions on its own, and you should not change prescription hormones or thyroid medication without medical guidance.
Hormone results are method- and timing-sensitive; reference ranges vary by lab, cycle phase, pregnancy status, and medication use, so interpretation should be done in context of your collection date and clinical history.
Lab testing
Order the Vitals Vault Comprehensive Female Hormone Panel
Schedule online, results typically within about a week
Clear reporting and optional clinician context
HSA/FSA eligible where applicable
Get this panel with Vitals Vault
Vitals Vault lets you order a comprehensive female hormone lab panel without needing to coordinate multiple separate orders. You get a single set of results that can be reviewed together, which matters because ovarian hormones (like estradiol and progesterone), pituitary signals (LH and FSH), and androgens (like testosterone and DHEA-S) often change in related ways.
After your results are in, you can use PocketMD to ask practical questions such as how to think about cycle timing, what patterns can suggest anovulation (not ovulating), or when it makes sense to repeat the panel at a different point in your cycle. If you are already working with a clinician, the panel can also give you a clearer, organized dataset to bring to that visit.
If you are tracking change over time—PCOS management, perimenopause progression, or therapy monitoring—retesting the same panel can help you compare like-with-like rather than mixing different test menus and reference ranges.
- One order that bundles multiple hormone and thyroid-related markers
- Designed for pattern-based interpretation (cycle + pituitary + androgen + thyroid context)
- PocketMD support for next-step questions and retest planning
- Useful for trending over time when you repeat with similar timing
Key benefits of the Vitals Vault Comprehensive Female Hormone Panel
- Shows your ovarian hormone picture (estrogen and progesterone) alongside pituitary signals that drive the cycle (LH and FSH).
- Helps you spot patterns consistent with anovulation or luteal-phase issues when progesterone and gonadotropins do not match your cycle timing.
- Adds androgen context (testosterone, DHEA-S, SHBG) that can clarify acne, hair changes, and PCOS-like symptoms.
- Includes thyroid screening markers that often overlap with “hormone” symptoms like fatigue, weight change, and cycle disruption.
- Supports fertility planning by helping you choose smarter timing for follow-up tests (for example, mid-luteal progesterone or day-3 gonadotropins).
- Improves medication and supplement conversations by showing how binding proteins and related hormones may shift together.
- Makes it easier to trend changes over time using one consistent panel rather than piecemeal single tests.
What is the Vitals Vault Comprehensive Female Hormone Panel?
The Vitals Vault Comprehensive Female Hormone Panel is a bundled set of blood tests that measures multiple hormones and related markers involved in reproductive function and common hormone-related symptoms. Instead of focusing on one analyte, the panel is designed to capture a broader “signal” across the hypothalamic–pituitary–ovarian (HPO) axis (the system that regulates ovulation and menstrual cycles), androgen production, and thyroid function.
A key reason to use a panel is that many hormones are interdependent. For example, estradiol (a primary estrogen) and progesterone change dramatically across the cycle, while LH (luteinizing hormone) and FSH (follicle-stimulating hormone) reflect pituitary signaling that can shift with age, ovarian reserve, stress, and certain conditions. Androgens like testosterone and DHEA-S can be elevated, normal, or low depending on PCOS patterns, adrenal contribution, medication use, and changes in SHBG (sex hormone–binding globulin), which affects how much hormone is “free” versus bound.
Timing matters. A result that looks “low” or “high” on paper may be appropriate for your cycle day, postpartum status, or whether you are using hormonal contraception. The most useful interpretation usually comes from pairing your lab timing (for example, early follicular vs mid-luteal) with your symptoms and goals.
If you are in perimenopause, the panel can help you see whether fluctuating estradiol and progesterone are occurring alongside rising or variable FSH/LH, and whether thyroid markers could be contributing to overlapping symptoms such as sleep disruption, anxiety, palpitations, or fatigue.
What do my panel results mean?
Patterns that can look “low” on this panel
A “low” pattern often means one of two things: your labs were drawn at a time when certain hormones are normally lower (for example, progesterone outside the mid-luteal window), or there is reduced hormone production/signaling relative to your timing and symptoms. Examples include low progesterone with low-to-normal LH/FSH that may fit anovulation or a missed timing window; low estradiol with higher FSH that can be seen as ovarian function changes with age; or low free/bioavailable sex hormones when SHBG is high (sometimes influenced by estrogen exposure, thyroid status, or certain medications). Low thyroid hormones or an elevated TSH pattern can also overlap with cycle changes, low energy, and mood symptoms, so it is important to read reproductive markers alongside thyroid markers rather than assuming everything is “just estrogen.”
Patterns that are often considered “optimal”
An “optimal” pattern is less about one perfect number and more about internal consistency: hormones that match your cycle timing, symptoms, and life stage. For example, estradiol and LH/FSH that fit your follicular phase, followed by a progesterone level consistent with ovulation when drawn mid-luteal, is often reassuring when cycles are regular. Androgen markers that are in range with a balanced SHBG can align with stable skin and hair symptoms. Thyroid markers that are in range and stable can reduce the chance that thyroid dysfunction is driving fatigue, weight change, or cycle disruption. If you feel well and your results are consistent with your timing, the most useful next step is often trending—repeating the panel with similar timing if your symptoms change.
Patterns that can look “high” on this panel
A “high” pattern can reflect normal physiology (such as an LH surge near ovulation or higher estradiol at certain cycle points), medication effects, or a pattern worth follow-up. Higher androgens (testosterone and/or DHEA-S) with lower SHBG can align with PCOS-type symptoms like acne, unwanted hair growth, or scalp hair thinning, especially when paired with irregular cycles. Higher prolactin can suppress ovulation in some people and may be associated with cycle changes or nipple discharge, but it is also sensitive to stress, sleep, and recent exercise. Higher FSH (especially if persistent and paired with lower estradiol) can occur with perimenopause or diminished ovarian reserve patterns. Thyroid patterns can also skew “high” or “low” depending on TSH and free hormone levels, and thyroid shifts can amplify palpitations, anxiety, heat intolerance, or menstrual changes.
Factors that influence female hormone panel results
Cycle timing is the biggest driver: estradiol, LH, and FSH vary across the follicular phase and around ovulation, while progesterone is most informative when measured about 7 days after ovulation (often called “mid-luteal,” which is not the same calendar day for everyone). Hormonal contraception, fertility medications, hormone therapy, and some supplements can change measured levels and SHBG. Stress, poor sleep, intense exercise, acute illness, and recent weight change can affect ovulation and pituitary signaling. Prolactin is especially sensitive to stress, nipple stimulation, and certain medications. Thyroid markers can shift with pregnancy/postpartum changes, iodine intake, and thyroid medication timing. Because multiple systems interact, the most reliable interpretation comes from looking at the full pattern, your collection timing, and whether you are trending results over time.
What’s included in this panel
- Absolute Band Neutrophils
- Absolute Basophils
- Absolute Blasts
- Absolute Eosinophils
- Absolute Lymphocytes
- Absolute Metamyelocytes
- Absolute Monocytes
- Absolute Myelocytes
- Absolute Neutrophils
- Absolute Nucleated Rbc
- Absolute Plasma Cells
- Absolute Prolymphocytes
- Absolute Promyelocytes
- Absolute Reactive Lymphocytes
- Albumin
- Albumin/Globulin Ratio
- Alkaline Phosphatase
- Alt
- Ast
- Band Neutrophils
- Basophils
- Bilirubin, Total
- Blasts
- Bun/Creatinine Ratio
- Calcium
- Carbon Dioxide
- Chloride
- Chol/Hdlc Ratio
- Cholesterol, Total
- Creatinine
- Dhea Sulfate
- Egfr
- Eosinophils
- Estradiol
- Estrogens, Total, Ia
- Fsh
- Globulin
- Glucose
- Hdl Cholesterol
- Hematocrit
- Hemoglobin
- Hemoglobin A1C
- Ldl-Cholesterol
- Ldl/Hdl Ratio
- Lh
- Lymphocytes
- Mch
- Mchc
- Mcv
- Metamyelocytes
- Monocytes
- Mpv
- Myelocytes
- Neutrophils
- Non Hdl Cholesterol
- Nucleated Rbc
- Plasma Cells
- Platelet Count
- Potassium
- Pregnenolone, Lc/Ms
- Progesterone
- Prolymphocytes
- Promyelocytes
- Protein, Total
- Rdw
- Reactive Lymphocytes
- Red Blood Cell Count
- Sex Hormone Binding Globulin
- Sodium
- T3, Free
- T4, Free
- Testosterone, Free
- Testosterone, Total, Ms
- Triglycerides
- Tsh
- Urea Nitrogen (Bun)
- Vitamin D, 25-Oh, D2
- Vitamin D, 25-Oh, D3
- Vitamin D, 25-Oh, Total
- White Blood Cell Count
Frequently Asked Questions
Do I need to fast for this hormone panel?
Fasting is not always required for hormone testing, but your lab instructions should be followed because some add-on markers and certain lab workflows prefer a morning, fasted draw. If cortisol is included, a morning collection time is often important. If you are unsure, order first and confirm the collection instructions provided with your requisition.
What cycle day should I test?
It depends on what you are trying to learn. Early follicular testing (often cycle day 2–5) is commonly used to interpret baseline LH/FSH and estradiol. Progesterone is most informative mid-luteal—about 7 days after ovulation—rather than a fixed calendar day. If your cycles are irregular, you can still test, but interpretation should focus on patterns and may benefit from repeating with better-timed collection.
Can this panel help with PCOS patterns?
It can. PCOS-related lab patterns often involve androgen markers (like testosterone, DHEA-S, androstenedione), SHBG changes, and ovulatory patterns reflected by progesterone and gonadotropins. Labs alone do not diagnose PCOS, but a comprehensive panel can provide useful context to discuss symptoms, cycle history, and imaging with a clinician.
How do I interpret the panel if I’m in perimenopause?
Perimenopause is often characterized by variability rather than a single steady shift. You may see fluctuating estradiol and progesterone with more variable or rising FSH/LH over time. Because day-to-day variation can be large, trending results (with similar timing when possible) and focusing on symptom alignment is often more informative than reacting to one isolated value.
What if I’m on hormonal birth control or hormone therapy?
Hormonal contraception and hormone therapy can change measured hormone levels and SHBG, and they can suppress ovulation—making progesterone patterns look “low” even when that is expected. The panel can still be useful, but the interpretation should be specific to your medication type, dose, and timing. Do not stop prescribed hormones just to “get a clean test” without medical guidance.
Is it better to order a panel or individual hormone tests?
A panel is often more useful when your symptoms could involve multiple systems (cycle + androgens + thyroid) or when you want a cohesive interpretation. Individual tests can be appropriate for a narrow question, but they can miss context—like high SHBG lowering free hormones, or thyroid patterns contributing to symptoms that get labeled as “estrogen imbalance.”
How often should I repeat this panel?
Retesting depends on your goal. If you are adjusting therapy or tracking a condition, repeating in 8–12 weeks is common, but cycle-based questions may require repeating at a specific phase (for example, mid-luteal progesterone). If you are trending perimenopause changes, periodic retesting with consistent timing can be more helpful than frequent testing.