Vaccination Status Test Panel Basic Blood Test Panel
This blood test panel checks vaccine-related immunity markers (antibodies) for several infections so you can confirm protection and plan boosters.
This panel bundles multiple biomarker tests in one order—your report explains how results fit together.
This is a lab panel, meaning you get multiple related tests in one blood draw. The Vaccination Status Test Panel Basic is designed to answer a practical question: do your labs show evidence of immunity to several common vaccine-preventable infections, or is there a reason to consider updating vaccines or repeating a dose series?
Because immunity is not one number, this panel looks at a set of antibody (“titer”) results together. Your pattern across the panel can help you prioritize next steps—especially if your vaccine records are incomplete, you need documentation for work or school, or you want a clearer baseline for preventive care.
Do I need this panel?
You might consider a vaccination status lab panel if you do not have reliable vaccine records, you are unsure whether childhood vaccines “took,” or you need objective documentation for employment, school, travel, or healthcare-related requirements.
This panel can also be useful if you are planning pregnancy, living with or caring for someone who is immunocompromised, or you want to reduce avoidable infection risk as part of a preventive health plan. In those situations, knowing your immunity status can be more actionable than guessing based on memory.
If you recently received a vaccine or booster, a titer panel can help confirm response—but timing matters. Antibody levels can take weeks to rise, and some vaccines are not best evaluated by titers alone.
Your results should support clinician-directed care and shared decision-making, not self-diagnosis. A “non-immune” result does not automatically mean you are unsafe or sick; it usually means you and your clinician should discuss revaccination, repeat testing, or whether a different type of documentation is appropriate.
This panel uses blood-based antibody testing (serology). Different labs use different assays and cutoffs, so interpretation should follow the reference ranges and comments on your report.
Lab testing
Order labs to measure Vaccination Status Test Panel
Basic
from $1,637.99 at Quest Diagnostics
About 1 week
Schedule online — results typically within a week
Clear next steps
Guidance included, with follow-up care available
HSA / FSA
Eligible for pre-tax health spending accounts
Get this panel with Vitals Vault
Vitals Vault makes it straightforward to order a vaccination status lab panel when you want clarity and a clean baseline. You get a single order that bundles multiple immunity markers, so you are not piecing together separate tests or trying to decide which titers matter most.
Once your results are back, the most important step is turning a page of numbers into priorities. PocketMD can help you review the pattern across the panel—what looks clearly immune, what is borderline, and what may warrant a booster, a repeat series, or a conversation about timing and documentation.
If your goals sharpen after you see your baseline, you can retest this same profile later to confirm response or add a more focused panel to match your next question (for example, cardiometabolic or fitness-focused labs).
- One order for multiple vaccine-related immunity markers
- Designed for baseline building and repeatable follow-up
- PocketMD support to organize next steps from a multi-result report
Key benefits of Vaccination Status Test Panel Basic
- Confirms immunity status across several common vaccine-preventable infections in one panel.
- Helps you prioritize which vaccines or boosters to discuss instead of guessing from old records.
- Supports documentation needs for work, school, travel, or clinical clearance when titers are accepted.
- Identifies mixed patterns (immune to some infections, not others) that are easy to miss when tests are ordered one-by-one.
- Provides a baseline you can repeat after vaccination to check for an antibody response when clinically appropriate.
- Adds context for preventive planning if you are around high-risk individuals or entering higher-exposure settings.
- Reduces “panel overload” by grouping related results into a single, interpretable immunity snapshot.
What is the Vaccination Status Test Panel Basic panel?
The Vaccination Status Test Panel Basic is a bundled set of blood tests that look for antibodies—proteins your immune system makes after vaccination or past infection. These antibody results are often called titers. A positive or “immune” titer generally suggests your immune system recognizes that pathogen and can respond more quickly if you are exposed.
This panel is not a direct measurement of every part of immunity. Antibodies are only one component; immune memory also involves specialized cells (T cells and B cells) that are not captured by routine serology. That is why a negative or low antibody result does not always equal “no protection,” and why some vaccines are not reliably assessed with titers.
In practice, a vaccination status panel is most helpful for:
1) confirming immunity when records are missing or uncertain, 2) documenting immunity when a program accepts serology instead of vaccine dates, and 3) guiding a targeted revaccination plan when certain markers are non-immune.
Your clinician may also consider your age, medical history, immune status, pregnancy plans, and the specific vaccine type (live-attenuated vs inactivated vs recombinant) when deciding whether to revaccinate, repeat a series, or accept prior documentation.
What do my panel results mean?
Low or non-immune pattern across the panel
If several markers come back negative, non-immune, or below the lab’s protective threshold, it often points to incomplete vaccination, waning antibody levels over time, or lack of prior exposure. This pattern is most actionable when it matches your history (for example, you are unsure you completed a series) or when you need proof of immunity for a specific requirement. Your next step is usually to review which vaccines are recommended for your age and risk, and whether revaccination or repeating a series is appropriate. If you have a condition or medication that can blunt vaccine response, your clinician may also consider timing, additional doses, or alternative documentation.
Immune pattern for most markers
If most results are positive/immune, the panel is reassuring: it suggests you have measurable antibody recognition for the infections tested. In many real-world situations, this is enough to meet documentation needs and to reduce uncertainty about your baseline. Even with an overall immune pattern, you may still see one marker that is borderline or negative; that does not automatically mean you are “unprotected,” but it is a useful flag to discuss whether a booster is recommended, whether the lab’s cutoff is strict, and whether your exposure risk makes follow-up worthwhile.
High-positive titers or very strong antibody signals
Very high antibody levels typically reflect a strong response from prior vaccination, a recent booster, or past infection. In most cases, higher is not “dangerous”—it is simply a stronger signal on the assay. The key is context: if you were recently vaccinated, high results may be expected; if you were not, high titers can still occur from remote vaccination or natural infection. Because different labs report titers differently (index values, IU/mL, or qualitative immune/non-immune), the most meaningful interpretation is whether you meet the lab’s protective threshold and whether the result aligns with your history and goals.
Factors that influence vaccination status panel results
Your pattern across this panel can be influenced by timing (testing too soon after a vaccine may miss the rise in antibodies), the type of vaccine and how well titers correlate with protection for that disease, and natural infection history. Age, pregnancy, and immune-modifying conditions or medications can also affect antibody levels and vaccine response. Lab-to-lab differences matter: assays use different targets and cutoffs, so a “borderline” result may warrant repeat testing at the same lab if you are tracking change. Finally, antibody levels can decline over time even when immune memory persists, which is why clinical recommendations may favor revaccination based on risk and history rather than titers alone.
What’s included in this panel
- Bordetella Pertussis Toxin(Pt) Ab (Igg), Ia
- Diphtheria Antitoxoid
- Measles Ab (Igg), Immune Status
- Mumps Virus Ab (Igg), Immune Status
- Polio 1 Titer
- Polio 3 Titer
- Rubella Ab (Igg), Immune Status
- Tetanus Antitoxoid
- Varicella Zoster Virus Antibody (Igg)
Similar tests and next-step panels
Frequently Asked Questions
Do I need to fast for the Vaccination Status Test Panel Basic?
Fasting is usually not required for antibody (titer) testing. If you are combining this panel with other labs (like lipids or glucose/insulin), follow the fasting instructions for those tests. When in doubt, use the instructions on your lab order.
What does “immune,” “equivocal,” or “non-immune” mean on a titer report?
These are lab interpretations based on a cutoff specific to the assay. “Immune/positive” generally means your antibody level meets the lab’s threshold associated with prior vaccination or infection. “Equivocal/borderline” means the result is near the cutoff and may warrant repeat testing or a clinical decision based on risk. “Non-immune/negative” means antibodies were not detected at a protective level on that assay, which often leads to a discussion about vaccination or revaccination.
If one marker is non-immune but the rest are immune, what should I do?
A mixed pattern is common. The next step depends on which infection is non-immune, your exposure risk, and whether titers are considered reliable proof of protection for that vaccine. Many people simply need a targeted booster or repeat series for the specific vaccine, while others may only need documentation of vaccination rather than titers. Review the result with a clinician if you are making decisions for work/school clearance, pregnancy planning, or immunocompromised household contacts.
Is it better to order a panel instead of ordering titers one at a time?
A panel is often easier when your goal is a baseline or documentation across several vaccines because it reduces guesswork and helps you interpret results as a set. Ordering one at a time can make sense if you already know exactly which immunity proof you need (for example, only hepatitis B for a job requirement).
How soon after a vaccine or booster should I check titers?
Antibodies typically rise over weeks, not days. Many clinicians wait at least 2–4 weeks after vaccination to check a response, and sometimes longer depending on the vaccine and the reason for testing. If you are checking response because of immune suppression or an occupational requirement, follow the timing guidance you were given for that specific situation.
Can I be protected even if my antibody level is low?
Yes, sometimes. Antibody levels can decline over time while immune memory persists, and protection is not always perfectly captured by a single antibody measurement. That said, if you need formal documentation or you are in a higher-risk setting, clinicians often use established cutoffs and public health guidance to decide whether revaccination is the simplest, safest next step.