Stonerisk Panel
Stonerisk Panel is a urine-focused lab panel that measures stone-forming minerals, inhibitors, and acidity to guide prevention and retesting.
This panel bundles multiple biomarker tests in one order—your report explains how results fit together.
The Stonerisk Panel is not one lab value—it is a bundled lab panel that looks at several urine chemistry markers together to estimate your kidney stone risk pattern. Instead of guessing from a single number, you get a more complete picture of whether your urine is concentrated, too acidic or alkaline, high in stone-forming minerals, or low in natural inhibitors that help keep crystals from forming.
Do I need this panel?
You may consider the Stonerisk Panel if you have had a kidney stone before, have recurrent flank pain with a history of stones, or want a clearer prevention plan than “drink more water.” This panel is especially helpful when you are trying to understand what type of stone risk you have (for example, calcium oxalate versus uric acid patterns) and what to change first.
This panel can also be useful if you are unsure whether a random urine test is “good enough” or whether you need a more structured evaluation. A multi-marker panel helps because stone risk is rarely explained by a single result—urine volume, pH (acidity), calcium, oxalate, uric acid, citrate, sodium, and other markers interact.
If you are worried about kidney function (eGFR), protein in the urine, or exposure concerns (such as heavy metals), this panel can still be a strong starting point for stone chemistry—but you may need companion blood and urine kidney baseline testing to answer those other questions.
Your results should support clinician-directed care and prevention planning, not self-diagnosis. If you have fever, severe pain, vomiting, or trouble urinating, treat that as urgent medical care rather than a testing decision.
This lab panel combines multiple urine chemistry measurements; reference ranges and units can vary by laboratory, and interpretation depends on how the sample was collected (spot vs timed/24-hour).
Lab testing
Order the Stonerisk Panel
Schedule online, results typically within about a week
Clear reporting and optional clinician context
HSA/FSA eligible where applicable
Get this panel with Vitals Vault
Vitals Vault makes it straightforward to order a bundled lab panel when you want a prevention-focused view of kidney stone risk. Instead of ordering individual tests one by one, you can run a coordinated panel designed to be interpreted as a pattern.
After you receive your results, PocketMD can help you connect the dots across markers—such as how urine concentration and sodium relate to urine calcium, or how urine pH changes the risk of uric acid versus calcium phosphate stones. That context matters because “normal” on one line item can still be part of a high-risk pattern when paired with other results.
If your goal is to build a longer-term plan, you can use this panel as a baseline, make targeted changes (hydration, diet, medication with your clinician when appropriate), and retest to see whether the overall risk pattern is improving.
- Order a single bundled panel designed for stone-risk patterns
- Use PocketMD to review how multiple markers fit together
- Retesting-friendly for tracking prevention changes over time
Key benefits of the Stonerisk Panel
- Shows your stone risk as a pattern across urine volume, acidity (pH), minerals, and inhibitors—not a single isolated value.
- Helps distinguish common risk profiles (for example, concentrated urine plus high calcium vs acidic urine plus high uric acid).
- Identifies low citrate (a natural inhibitor) and other modifiable factors that often respond to targeted nutrition or therapy.
- Supports more precise hydration and sodium goals by tying them to urine concentration and calcium handling.
- Provides a clearer reason to retest after changes, so you can confirm the whole risk pattern is moving in the right direction.
- Reduces confusion between random urine results and timed collections by emphasizing collection context in interpretation.
- Pairs well with kidney baseline blood-and-urine testing when you also want eGFR, proteinuria, or broader renal health context.
What is the Stonerisk Panel?
The Stonerisk Panel is a multi-marker lab panel that evaluates urine chemistry factors linked to kidney stone formation. Stones form when urine becomes supersaturated—meaning there is more of a crystal-forming substance (like calcium, oxalate, or uric acid) than can stay dissolved—especially when urine is concentrated or the pH favors certain crystals.
This panel is designed to capture the main drivers of that process:
• Concentration and dilution: If urine volume is low, many stone-forming substances become more concentrated. Even “borderline” mineral levels can become risky when urine is consistently concentrated.
• Urine acidity (pH): Urine pH strongly influences which crystals form. More acidic urine tends to increase uric acid stone risk, while higher (more alkaline) urine can increase calcium phosphate risk in susceptible people.
• Stone-forming loads: Calcium, oxalate, uric acid, sodium, and related markers help estimate how much “building material” is present for stones.
• Natural inhibitors: Citrate is a key inhibitor that binds calcium and reduces crystal formation. Low citrate can be a major, treatable contributor to calcium-based stones.
Because these markers interact, the most useful interpretation is not “one number is high,” but “your overall profile points toward a specific stone-risk mechanism.” That is what a panel is built to do.
What do my panel results mean?
Lower-risk patterns on this panel
A lower-risk pattern usually looks like adequate urine volume (more dilution), no strong pH extreme, and no major elevations in stone-forming substances relative to inhibitors. In practice, that might mean your urine is not consistently concentrated, calcium and oxalate are not both trending high together, uric acid risk markers are not clustering with a low pH, and citrate is sufficient to help prevent crystal growth. If you have had stones despite a lower-risk pattern, your clinician may consider factors not captured by routine chemistry (stone composition, anatomy, infections, or timing effects) and may recommend repeating the panel under typical day-to-day conditions.
More optimal patterns on this panel
A more optimal pattern is one where the markers align in a protective direction: urine volume supports dilution, sodium and other dietary-linked markers are not pushing calcium higher, citrate is present at a supportive level, and urine pH is in a range that does not strongly favor a specific stone type. “Optimal” does not mean you can ignore symptoms, but it often means your current hydration and nutrition pattern is not creating a strong chemical environment for stones. If you are making prevention changes, this is the kind of coordinated improvement you want to see across multiple line items, not just a single number moving.
Higher-risk patterns on this panel
A higher-risk pattern often shows up as clusters: low urine volume (concentrated urine) plus higher calcium and/or oxalate; very acidic urine (low pH) alongside higher uric acid-related markers; or higher pH with signals that can favor calcium phosphate crystallization. Another common higher-risk pattern is low citrate combined with higher calcium—removing a key inhibitor while increasing available calcium for crystals. When multiple markers point in the same direction, the overall risk can be higher even if each individual result is only mildly abnormal. Your clinician may use these patterns to prioritize interventions (hydration targets, sodium reduction, oxalate strategy, citrate support, or medication when appropriate) and to decide when to retest.
Factors that influence this panel
Your collection method and recent habits can meaningfully shift results. A spot (random) urine sample reflects what was happening around that time, while a timed or 24-hour collection better reflects daily totals; the same person can look “low risk” on one day and “high risk” on another if hydration, sweating, or diet changed. High sodium intake can increase urine calcium in many people, and low fluid intake (including heavy exercise or heat exposure) can concentrate nearly every marker. Diet patterns (animal protein load, oxalate-rich foods, calcium intake timing), supplements (vitamin C can raise oxalate in some people), and certain medications can shift urine pH and citrate. If you have chronic kidney disease, bowel disease, recurrent diarrhea, gout, or frequent urinary tract infections, those conditions can also change stone-risk chemistry and should be part of the interpretation.
What’s included in this panel
- Ammonium, 24 Hour Urine
- Brushite
- Calcium, 24 Hour Urine
- Calcium Oxalate
- Citric Acid,24 Hour Urine
- Creatinine, 24 Hour Urine
- Magnesium, 24 Hour Urine
- Oxalate, 24 Hour Urine
- Ph Urine
- Phosphorus, 24 Hour Urine
- Potassium, 24 Hour Urine
- Sodium, 24 Hour Urine
- Sodium Urate
- Struvite
- Sulfate, 24 Hour Urine
- Supersaturation Index With Respect To:
- The Patient Has:
- Total Urine Volume
- Uric Acid
- Uric Acid, 24 Hour Urine
Frequently Asked Questions
Is the Stonerisk Panel a blood test or a urine test?
This is a urine-focused lab panel. It combines multiple urine chemistry markers that are interpreted together to estimate kidney stone risk patterns. If you also need kidney function context (like eGFR) or proteinuria evaluation, you may want a companion blood-and-urine kidney baseline panel.
Do I need a 24-hour urine collection for this panel?
Timed collections (often 24-hour) are commonly used for stone-risk evaluation because they better reflect daily totals, but some versions of stone-risk testing can be done as a spot sample depending on the product and clinical goal. The key is that interpretation changes based on collection type—your results should be read with that context in mind.
Do I need to fast before taking this panel?
Fasting is usually not required for urine stone-risk chemistry, but your clinician may recommend a “typical day” approach so the results reflect your usual diet and hydration. Follow the collection instructions provided with your order, especially around timing, storage, and completing the full collection if it is timed.
How do I interpret multiple results without getting overwhelmed?
Start with the pattern: (1) Is urine concentrated (low volume/high specific gravity)? (2) Is urine pH pushing risk toward uric acid (more acidic) or calcium phosphate (more alkaline)? (3) Are stone-forming loads elevated (calcium, oxalate, uric acid, sodium)? (4) Are inhibitors low (especially citrate)? PocketMD can help you summarize the pattern and identify the most actionable next steps.
What does low citrate mean on a stone-risk panel?
Low citrate means you may have less of a natural inhibitor that helps keep calcium from forming crystals. When low citrate appears alongside higher urine calcium or concentrated urine, it can meaningfully increase calcium-based stone risk. Your clinician may discuss dietary strategies or citrate-based therapy depending on your overall profile.
Can a normal result still mean I’m at risk for stones?
Yes. Stone risk is about combinations and context. Mildly abnormal values can add up when urine is consistently concentrated, and a single “normal” value does not rule out risk if other markers cluster in a risky direction. Also, results can vary day to day, so repeating the panel under typical conditions can be useful.
Is it better to order this panel or individual urine tests separately?
A bundled panel is usually easier to interpret because the markers are chosen to work together (for example, pairing pH with uric acid markers and supersaturation calculations, or pairing calcium with sodium and citrate). Ordering individual tests can miss the relationships that drive risk patterns.