PLR (Platelet:Lymphocyte)

• PLR combines information about inflammation and thrombosis in a single metric
• Elevated PLR is associated with worse outcomes in cardiovascular disease, various cancers, and chronic inflammatory conditions
• It predicts mortality and disease progression, particularly in oncology
• PLR is useful for risk stratification and monitoring treatment response

Platelets / Lymphocytes

• The Platelet-to-Lymphocyte Ratio (PLR) is an inflammatory marker that reflects the balance between platelet activation (thrombotic potential) and lymphocyte count (immune surveillance)

• High PLR: Usually asymptomatic as a standalone finding
• Associated conditions may cause fatigue, unexplained weight loss, shortness of breath, or symptoms related to underlying disease processes

• High PLR: Chronic inflammation, cancer, cardiovascular disease, autoimmune conditions, infections, and reactive thrombocytosis.
• Low PLR: May indicate bone marrow disorders, severe infections, or certain autoimmune conditions affecting platelets.