LDL-C/ApoB Ratio

• A lower ratio suggests more small, dense LDL particles, which are more atherogenic
• Since each LDL particle has one ApoB molecule, this ratio reflects particle size
• Small dense LDL penetrates arterial walls more easily and is more prone to oxidation
• This ratio helps refine cardiovascular risk assessment

LDL-C / ApoB

• The LDL-C to ApoB ratio indicates the cholesterol content per LDL particle, helping identify whether particles are large (cholesterol-enriched) or small and dense

• Low ratio (small dense LDL): No direct symptoms but indicates higher cardiovascular risk
• May be associated with metabolic syndrome features

• Low ratio: Metabolic syndrome, insulin resistance, diabetes, high triglycerides, familial combined hyperlipidemia
• Higher ratio: Larger, more buoyant LDL particles (generally more favorable)