Keto Lab Panel
The Keto Lab Panel is a blood test panel that tracks lipids, glucose/insulin trends, electrolytes, liver and kidney markers to guide safer keto.
This panel bundles multiple biomarker tests in one order—your report explains how results fit together.
Keto can make you feel better fast, but the scale, your energy, and your labs do not always move in the same direction. This lab panel bundles the most useful blood tests to check how a low‑carb approach is affecting your cardiometabolic risk markers, hydration/electrolytes, and organ function—so you can adjust your plan based on data, not guesswork.
Do I need this panel?
You may want the Keto Lab Panel if you are starting or restarting keto, tightening carbs after a plateau, or experimenting with higher fat intake and you want objective feedback beyond weight and ketone readings. A single number (like ketones) cannot tell you whether your lipid pattern, glucose control, or electrolyte status is moving in a healthy direction.
This panel is especially useful if you notice a mismatch between how you feel and what you see on the scale—such as stalled weight loss, new fatigue, headaches, constipation, muscle cramps, palpitations, or reduced exercise tolerance. These symptoms can overlap with dehydration, sodium/potassium shifts, inadequate calories or protein, or an overly aggressive deficit.
It is also reasonable to check a panel if you have a personal or family history of high LDL cholesterol, early heart disease, fatty liver, prediabetes, hypertension, kidney stones, or if you are using medications that change appetite or glucose (including GLP‑1 medications). Keto can improve triglycerides and glucose for many people, but some people see a meaningful rise in LDL‑related markers, and you want to catch that early.
This panel supports clinician-directed care and shared decision-making. Your results are best interpreted alongside your medical history, medications, and goals rather than used for self-diagnosis.
Reference ranges and units vary by lab, and this panel includes multiple tests that should be interpreted together rather than in isolation.
Lab testing
Order labs to measure Keto Lab Panel
from $190.99 at Quest Diagnostics
About 1 week
Schedule online — results typically within a week
Clear next steps
Guidance included, with follow-up care available
HSA / FSA
Eligible for pre-tax health spending accounts
Get this panel with Vitals Vault
Vitals Vault makes it straightforward to order a keto-focused lab panel and get a clear, plain-language interpretation of how your results fit together. Instead of chasing individual tests, you get a bundled view of the markers that most often shift with low‑carb eating: lipids, glucose/insulin trends, electrolytes, and core liver/kidney function.
After you get your results, you can use PocketMD to ask targeted questions like: “My LDL markers rose but triglycerides dropped—what does that pattern usually mean?” or “Do my electrolytes suggest I should change sodium, potassium, or fluids?” You can also use your results to plan a sensible retest cadence (for example, after 8–12 weeks of a stable routine) so you can separate temporary adaptation changes from longer-term trends.
If your results suggest you need a broader workup—such as deeper insulin resistance testing, inflammation markers, thyroid evaluation, or more comprehensive cardiometabolic risk—Vitals Vault can help you widen the lens with additional panels.
- Order online and test through a national lab network
- Panel-style interpretation that connects related markers
- PocketMD support for next-step questions and retest planning
Key benefits of the Keto Lab Panel
- See how keto is affecting your lipid pattern (not just total cholesterol).
- Track glucose control and insulin trends that may explain plateaus or cravings.
- Spot dehydration or electrolyte shifts that can drive headaches, cramps, or fatigue.
- Check liver and kidney markers to support safer long-term dieting choices.
- Create a baseline before keto and a clean comparison after you stabilize your routine.
- Interpret “mixed” results (for example, lower triglycerides with higher LDL markers) in context.
- Use objective data to decide whether to continue, modify macros, or widen your workup.
What is the Keto Lab Panel?
The Keto Lab Panel is a bundled set of blood tests designed to monitor common physiologic changes that can happen on a ketogenic or very low‑carbohydrate diet. Instead of measuring one analyte, it checks multiple systems that often move together when you change fueling strategy: lipid transport, glucose and insulin dynamics, hydration/electrolyte balance, and basic organ function.
Keto tends to lower insulin levels and shift your body toward using fat and ketones for energy. For many people, that improves triglycerides and raises HDL cholesterol. At the same time, some people see LDL cholesterol rise—sometimes substantially—especially with higher saturated fat intake, rapid weight loss, or certain genetic backgrounds. A panel helps you see whether changes are isolated (one marker drifting) or part of a broader pattern.
This panel is not a “ketone level” test. Ketones can confirm carbohydrate restriction, but they do not tell you whether your cardiometabolic risk markers are improving, whether you are under-fueling, or whether electrolyte shifts are contributing to symptoms. The goal is practical: help you make safer, more personalized adjustments while you experiment.
Because keto often overlaps with other variables—calorie deficits, intermittent fasting, increased exercise, GLP‑1 medications, alcohol changes, and supplement use—your best interpretation comes from looking at the full set of results together and comparing them to your baseline and your current routine.
What do my panel results mean?
When parts of the panel are low
“Low” on this panel often shows up as low fasting glucose, low fasting insulin, and lower triglycerides—changes that can be positive if you feel well and other markers are stable. However, low values can also signal under-fueling or adaptation stress when they occur alongside symptoms (fatigue, dizziness) or with electrolyte patterns that suggest low sodium/potassium. If kidney markers look concentrated (for example, higher BUN relative to creatinine) or electrolytes trend low, the issue may be hydration, salt intake, or overall calorie/protein adequacy rather than “not being in ketosis enough.”
An optimal keto-adapted pattern
Many people aim for a pattern that includes stable fasting glucose and HbA1c, lower triglycerides, and a higher HDL cholesterol, with liver enzymes and kidney function staying in a healthy range. In an optimal pattern, LDL-related markers are not rising sharply, and electrolytes support how you feel day to day (no frequent cramps, headaches, or palpitations). The most useful comparison is your own baseline: a shift toward better glucose/insulin markers and triglycerides without a concerning rise in LDL markers is often a sign your current approach is working for your body.
When parts of the panel are high
High results on a keto-focused panel commonly fall into two buckets: lipid markers and organ/electrolyte stress signals. If LDL cholesterol (and especially ApoB, when available on broader lipid panels) rises while triglycerides fall, you may be seeing a “mixed” response that needs context—dietary fat type, weight-loss rate, genetics, and overall energy balance can all contribute. High liver enzymes can reflect fatty liver, alcohol, medication effects, or intense training; high creatinine or abnormal electrolyte patterns can point to dehydration, supplement effects, or kidney strain. A single high value rarely tells the whole story—patterns and repeat testing after a stable routine are often more informative.
Factors that influence keto panel results
Your results can shift based on how long you have been low carb, how quickly you are losing weight, and what your diet is made of (saturated vs unsaturated fats, fiber intake, and total protein). Fasting duration and recent exercise can change glucose, triglycerides, and some kidney markers. Hydration and sodium intake strongly affect electrolytes and can change how you feel even when glucose and lipids look “good.” Medications and supplements matter too—GLP‑1 medications, thyroid medications, diuretics, creatine, and high-dose biotin are common examples that can affect appetite, labs, or interpretation. If you want the cleanest trend, test after a typical week, avoid unusually hard workouts the day before, and keep your fasting window consistent with prior tests.
What’s included in this panel
- Hs Crp
- T3, Free
- Glucose
- Insulin
- Lipoprotein (A)
- Tsh
- Hemoglobin A1C
- T4, Free
- Cholesterol, Total
- Hdl Cholesterol
- Triglycerides
- Ldl-Cholesterol
- Chol/Hdlc Ratio
- Ldl/Hdl Ratio
- Non Hdl Cholesterol
- Leptin
- Apolipoprotein B
- Ldl Particle Number
- Ldl Small
- Ldl Medium
- Hdl Large
- Ldl Pattern
- Ldl Peak Size
Similar tests and panels to consider
Frequently Asked Questions
Do I need to fast for the Keto Lab Panel?
Fasting is usually recommended because triglycerides and glucose/insulin markers are easier to compare over time when your pre-test conditions are consistent. If you are doing keto with intermittent fasting, try to use a similar fasting window each time you test so trends are meaningful. If you have diabetes or take glucose-lowering medications, follow your clinician’s safety guidance for fasting.
How soon after starting keto should I test?
A practical approach is to get a baseline before you change your diet (or as soon as possible when you start), then retest after you have been consistent for about 8–12 weeks. Early in keto, temporary shifts from water loss, training changes, or rapid weight loss can make interpretation noisy.
Why can LDL cholesterol go up on keto even if triglycerides go down?
Triglycerides often fall when carbohydrate intake drops and insulin levels improve. LDL-related markers can rise in some people due to changes in fat intake (especially saturated fat), weight-loss rate, genetics, and how your body packages and transports lipids. This is exactly where a panel and trend-based interpretation help—your overall pattern, baseline risk, and repeat results after a stable routine matter more than one snapshot.
Can this panel tell me if I am “in ketosis”?
Not directly. This panel focuses on safety and metabolic trends (lipids, glucose/insulin, electrolytes, liver and kidney markers). Ketosis is typically assessed with blood beta-hydroxybutyrate, breath acetone, or urine ketones. Many people use ketone testing for adherence, but it does not replace monitoring cardiometabolic risk markers.
What if I am on a GLP-1 medication while eating low carb?
GLP-1 medications can reduce appetite and change food intake, which can affect lipids, glucose, and electrolytes indirectly through lower calories and faster weight loss. If you are combining GLP-1 therapy with keto, this panel can help you watch for patterns like under-fueling, dehydration, or rapid lipid shifts. Bring your medication list and dosing schedule into the interpretation so your results are read in context.
Is it better to order individual tests instead of a panel?
Ordering tests one by one can miss important context. Keto changes multiple systems at once, and interpretation depends on patterns (for example, lipids plus glucose/insulin plus electrolytes). A panel is usually the simplest way to get a coherent snapshot from one blood draw and to repeat the same set for clean trend comparisons.
How often should I repeat the Keto Lab Panel?
If you are actively changing your diet, a repeat in about 8–12 weeks is common so you can see whether early changes persist. If your results are stable and you feel well, you may repeat less often. If you see a concerning shift (such as a large LDL rise, abnormal liver enzymes, or electrolyte issues with symptoms), you may want to recheck sooner after targeted changes, ideally with clinician guidance.