Coriander (Cilantro) F317 IgE Biomarker Testing
It measures IgE antibodies to coriander (cilantro) to assess allergy risk, with convenient ordering and clear Quest-network results from Vitals Vault.
With Vitals Vault, you have access to a comprehensive range of biomarker tests.

This test measures your immune system’s IgE response to coriander (also called cilantro). It is a targeted allergy blood test that looks for sensitization to a specific food-related allergen component labeled F317.
You might consider it if you notice symptoms after eating foods that commonly contain cilantro, such as salsa, curries, chutneys, soups, or spice blends. Because cilantro is often mixed with many other ingredients, a specific IgE result can help you and your clinician narrow down what is most likely driving reactions.
Your number does not diagnose an allergy by itself. It is one piece of evidence that should be interpreted alongside your symptom history and, when needed, other allergy testing.
Do I need a Coriander (Cilantro) F317 IgE test?
You may want this test if you get repeat symptoms soon after eating foods that may contain cilantro or coriander. Common allergy-type symptoms include itching or tingling in the mouth, hives, swelling of the lips or eyelids, nasal congestion, wheezing, nausea, vomiting, or abdominal cramping. In more serious cases, people can have trouble breathing or feel faint, which needs urgent medical care.
This test can also be useful if you have unexplained reactions to “mixed” foods (restaurant meals, spice blends, sauces) and you are trying to determine whether cilantro is a likely trigger versus another ingredient. It can help guide a safer elimination-and-rechallenge plan with your clinician rather than guessing.
You might not need this test if your symptoms are clearly non-allergic (for example, isolated heartburn hours later) or if you already have a confirmed coriander/cilantro allergy and you are not making any management changes. Testing is most helpful when the result will change what you do next, such as confirming a suspected trigger, deciding whether to carry emergency medication, or planning follow-up testing.
Use your result to support clinician-directed care, not to self-diagnose or to “prove” an allergy without considering your real-world reactions.
This is a laboratory-developed, CLIA-validated allergen-specific IgE blood test; results should be interpreted with your symptoms and clinician guidance, not used as a standalone diagnosis.
Lab testing
Order Coriander (Cilantro) F317 IgE testing
Schedule online, results typically within about a week
Clear reporting and optional clinician context
HSA/FSA eligible where applicable
Get this test with Vitals Vault
Vitals Vault makes it straightforward to order a coriander (cilantro) F317 IgE test when you want objective data to bring to your next conversation with a clinician. You can order your lab work and complete testing through a national lab network, then review your results in one place.
Once your result posts, PocketMD can help you translate the number into practical next steps to discuss: whether the pattern fits an IgE-mediated food allergy, what additional tests might clarify cross-reactivity, and when retesting is reasonable if your exposure or symptoms change.
If your goal is broader mapping (for example, multiple food or pollen triggers), you can add companion allergen tests or panels so you are not making decisions from a single data point.
- Order online and test through a national lab network
- Clear result tracking so you can compare over time
- PocketMD guidance to prepare for a clinician visit
Key benefits of Coriander (Cilantro) F317 IgE testing
- Helps identify whether your immune system is sensitized to coriander/cilantro as a potential trigger.
- Adds objective evidence when symptoms happen after mixed dishes where the ingredient list is unclear.
- Supports safer elimination planning by focusing on one suspected allergen instead of broad food restriction.
- Helps your clinician assess whether symptoms fit an IgE-mediated pattern that may warrant an action plan.
- Can guide follow-up testing for cross-reactivity with related pollens or foods when the history suggests it.
- Provides a baseline value you can trend if exposure changes or you are monitoring evolving symptoms.
- Pairs well with PocketMD interpretation so you can turn a lab number into a focused next-step discussion.
What is Coriander (Cilantro) F317 IgE?
Coriander (cilantro) F317 IgE is a blood test that measures allergen-specific immunoglobulin E (IgE) antibodies directed at coriander/cilantro. IgE is the antibody class involved in immediate-type allergic reactions. A higher coriander-specific IgE level means your immune system recognizes coriander proteins and is “sensitized,” which can increase the likelihood of allergy symptoms when you are exposed.
This is different from food intolerance. Intolerances are not driven by IgE and typically cause dose-dependent digestive symptoms without hives, swelling, or breathing symptoms.
Because cilantro is commonly used as a garnish or blended into sauces, people often do not realize they were exposed. A targeted IgE test can be a useful tool when your history suggests cilantro might be involved but you cannot confirm it from labels or restaurant meals.
Sensitization vs. clinical allergy
A positive IgE result means sensitization, not certainty of symptoms. Some people have measurable IgE but tolerate the food, while others react at relatively low IgE levels. Your clinician will weigh your result alongside the timing, consistency, and severity of your reactions.
Why cilantro reactions can be confusing
Cilantro is often paired with other common triggers such as onion, garlic, peppers, tomato, citrus, and various spices. If you react to a dish with many ingredients, testing can help you prioritize which specific allergens to evaluate next rather than avoiding entire cuisines.
What do my Coriander (Cilantro) F317 IgE results mean?
Low Coriander (Cilantro) F317 IgE
A low or undetectable result suggests you are unlikely to be sensitized to coriander/cilantro. If you still have symptoms after eating foods that may contain cilantro, it may point to a different ingredient, a non-IgE mechanism, or a reaction that is not allergy-related. Rarely, people can still react despite low IgE, so your symptom history still matters. If reactions are immediate and reproducible, discuss whether additional testing or a supervised food challenge is appropriate.
In-range / negative Coriander (Cilantro) F317 IgE
Most labs report a reference threshold where results below that cutoff are considered negative. In this context, “in-range” generally means the test did not detect clinically meaningful coriander-specific IgE. If you are avoiding cilantro due to fear of reactions, a negative result can support a more careful, clinician-guided plan to reassess whether cilantro is truly the trigger. If you have had severe symptoms, do not reintroduce on your own without medical guidance.
High Coriander (Cilantro) F317 IgE
A higher result indicates sensitization to coriander/cilantro and increases the probability that symptoms after exposure are IgE-mediated. The exact risk depends on your personal history; the number alone does not predict reaction severity. If you have had hives, swelling, wheezing, or rapid-onset symptoms after eating cilantro-containing foods, a positive result can support a clinician-created allergy action plan. Your clinician may also consider testing for other related allergens if cross-reactivity is suspected.
Factors that can influence Coriander (Cilantro) F317 IgE
Recent exposure is not required for IgE to be detectable, but IgE levels can change over time, especially in children or with changing environmental allergies. Cross-reactivity can occur when your immune system recognizes similar proteins across different plants or pollens, which can make a result positive even if cilantro is not the true trigger. Medications like antihistamines do not typically lower blood IgE results, but immune-modifying therapies and certain medical conditions can affect immune markers. Lab methods and reporting units can vary, so it helps to compare results from the same lab when trending.
What’s included
- Coriander/Cilantro (F317) Ige
Frequently Asked Questions
Do I need to fast for a coriander (cilantro) IgE blood test?
Fasting is not usually required for allergen-specific IgE testing. If you are getting other labs at the same time, follow the instructions for the full set of tests you ordered.
What does F317 mean on my allergy test?
F317 is the lab’s identifier for the coriander/cilantro allergen extract used for the specific IgE measurement. It helps standardize ordering and reporting across labs.
Can antihistamines affect coriander-specific IgE results?
Antihistamines can reduce symptoms and can affect skin-prick testing, but they generally do not change blood IgE results in a meaningful way. If you are on immune-modifying therapy, ask your clinician whether it could influence interpretation.
If my coriander IgE is positive, does that mean I will have anaphylaxis?
No. A positive result indicates sensitization and a higher likelihood of allergy symptoms, but it does not predict severity. Your past reactions, asthma history, and how quickly symptoms occur after exposure are often more informative for risk planning.
If my coriander IgE is negative, can I still be allergic?
It is less likely, but it is not impossible. Testing can miss some clinically relevant reactions, and some symptoms are not IgE-mediated. If your reactions are immediate, consistent, or severe, discuss next steps such as testing other suspected ingredients or a supervised oral food challenge.
How soon should I retest coriander (cilantro) IgE?
Retesting is usually considered when your symptoms change, you have had a long period of avoidance and are reassessing risk, or your clinician is monitoring a broader allergy pattern. Many people wait months rather than weeks because IgE trends typically change slowly.
Is this the same as a food sensitivity (IgG) test?
No. This test measures IgE, which is associated with immediate-type allergic reactions. IgG “food sensitivity” tests measure a different antibody class and do not diagnose IgE-mediated food allergy.