Celery F85 IgE (Allergen-Specific IgE) Biomarker Testing
It measures IgE antibodies to celery to help assess allergy risk and guide next steps, with convenient ordering and clear results through Vitals Vault/Quest.
With Vitals Vault, you have access to a comprehensive range of biomarker tests.

A Celery F85 IgE test looks for allergy-type antibodies in your blood that react to celery. It can help clarify whether your immune system is sensitized to celery when your symptoms are confusing, inconsistent, or hard to reproduce.
This test does not “prove” you will have a reaction every time you eat celery, and it cannot predict reaction severity on its own. It is most useful when it is interpreted alongside your history (what happened, how fast, how much celery, and whether there were other triggers).
If you have had hives, swelling, wheezing, vomiting, or throat tightness after eating celery—or you are avoiding celery because you are unsure—this result can help you and your clinician decide what to do next.
Do I need a Celery F85 IgE test?
You may want a Celery F85 IgE test if you get symptoms soon after eating celery, celery salt, soups/broths, or foods where celery is a hidden ingredient. Symptoms can include itching in your mouth, hives, facial or lip swelling, stomach upset, coughing, or wheezing. Some people notice symptoms only with raw celery, while others react to cooked forms as well.
Testing can also be helpful if you have seasonal allergies and notice mouth or throat itching with certain foods. Celery can be involved in cross-reactions related to pollen allergy (often called pollen–food allergy syndrome), where symptoms are usually milder but still worth clarifying.
You might also consider this test if you have had an unexplained allergic reaction and you are trying to identify a trigger, especially when celery was part of the meal. On the other hand, if you have never had symptoms with celery, a positive result may represent sensitization without clinical allergy, so it is usually not a “screening” test by itself.
Your result is meant to support clinician-directed care and shared decision-making, not self-diagnosis or self-challenges at home.
This is a laboratory-developed, CLIA-validated allergen-specific IgE blood test; results should be interpreted with your symptoms and clinician guidance and are not a standalone diagnosis.
Lab testing
Order the Celery F85 IgE test through Vitals Vault and schedule your blood draw when it works for you.
Schedule online, results typically within about a week
Clear reporting and optional clinician context
HSA/FSA eligible where applicable
Get this test with Vitals Vault
Vitals Vault lets you order a Celery F85 IgE blood test directly, then complete your draw at a participating lab location. It is a practical option when you want an objective data point to bring to your clinician, especially if you are deciding whether strict avoidance is necessary.
After your results post, you can use PocketMD to talk through what the number means in plain language, what follow-up testing might add (or not add), and how to think about retesting if your exposures or symptoms change.
If your history suggests a broader allergy pattern, you can also use Vitals Vault to map related testing over time rather than ordering a large set of labs all at once. That helps you focus on the questions that matter: “Is celery likely the trigger?” and “What is the safest next step?”
- Order online and complete your blood draw at a lab location
- Results you can share with your clinician and track over time
- PocketMD support for next-step questions and retest planning
Key benefits of Celery F85 IgE testing
- Helps identify whether your immune system is sensitized to celery (a common hidden ingredient).
- Adds objective context when symptoms are inconsistent or meals include many possible triggers.
- Supports safer planning around avoidance, label-reading, and eating outside the home.
- Can help distinguish likely IgE-mediated allergy from non-allergic food intolerance patterns.
- Guides whether related allergen testing or specialist evaluation is worth pursuing.
- Provides a baseline you can compare if symptoms change or after a period of avoidance.
- Pairs well with PocketMD so you can interpret the result in the context of your real-world reactions.
What is Celery F85 IgE?
Celery F85 IgE is a blood test that measures allergen-specific immunoglobulin E (IgE) antibodies directed against celery proteins. IgE is the antibody class involved in immediate-type allergic reactions, where symptoms can start within minutes to a couple of hours after exposure.
A positive celery-specific IgE result means your immune system has made IgE that recognizes celery. That is called sensitization. Sensitization increases the likelihood of clinical allergy, but it is not the same thing as a confirmed allergy, because some people have detectable IgE without reacting when they eat the food.
A negative result makes an IgE-mediated celery allergy less likely, but it does not rule out all adverse reactions to celery. Non-IgE mechanisms (like irritant effects, reflux triggers, or other food sensitivities) can still cause symptoms, and timing and reproducibility matter.
Your clinician may interpret this test alongside your symptom story, other allergy tests, and sometimes supervised food challenges when appropriate and safe.
How this differs from a skin prick test
Skin testing measures reactivity in the skin, while this test measures IgE in your blood. Either can be useful, and neither is perfect on its own. Blood testing can be convenient if you cannot stop antihistamines, have extensive eczema, or prefer a lab-based result you can trend.
Why celery can be tricky
Celery can appear in spice blends, broths, deli foods, and “natural flavors,” so exposure is not always obvious. In some people, celery reactions overlap with pollen-related cross-reactivity, which can make symptoms feel intermittent and dependent on season or the form of the food.
What do my Celery F85 IgE results mean?
Low or undetectable Celery IgE
A low or undetectable result generally suggests that an IgE-mediated celery allergy is less likely. If you still have symptoms, your clinician may look at timing (immediate vs delayed), other ingredients eaten at the same time, and non-allergic causes. If your reaction was severe or very convincing, additional evaluation may still be appropriate because no single test rules allergy in or out with 100% certainty.
In-range results (lab-specific reference)
Many labs report a numeric value with an interpretation threshold and sometimes an IgE “class.” Being below the lab’s positive cutoff is typically considered negative, but your history still matters. If you are in a borderline zone, your clinician may treat the result as supportive evidence rather than a final answer and may recommend repeat testing or a different approach depending on your symptoms.
High Celery IgE
A higher result means stronger sensitization to celery and increases the likelihood that celery can trigger immediate allergic symptoms. It still does not reliably predict how severe a reaction would be, because severity depends on many factors beyond the IgE number. If you have had systemic symptoms (trouble breathing, widespread hives, fainting, repetitive vomiting), treat this as a prompt to discuss a safety plan with your clinician rather than experimenting with exposure on your own.
Factors that can influence Celery IgE results
Your overall allergic tendency (atopy), seasonal pollen exposure, and other food or environmental allergies can affect IgE patterns. Recent reactions do not always cause an immediate rise, and IgE can persist even after long avoidance, so trends need time and context. Cross-reactivity can also play a role, where IgE recognizes similar proteins across different plants, which can produce a positive test without strong symptoms to celery itself. Medications like antihistamines do not typically lower blood IgE results, but immune-modifying therapies and certain medical conditions can complicate interpretation.
What’s included
- Celery (F85) Ige
Frequently Asked Questions
Do I need to fast for a Celery F85 IgE blood test?
Fasting is not usually required for allergen-specific IgE testing. If you are combining this with other labs that do require fasting, follow the instructions for the full set of tests you ordered.
What does a positive celery IgE test mean?
A positive result means you are sensitized to celery, meaning your immune system has IgE antibodies that recognize celery proteins. It increases the likelihood of a true allergy, but it does not confirm that you will react every time or predict how severe a reaction would be. Your symptom history is essential for interpretation.
Can I have a celery allergy with a negative IgE result?
It is less likely, but it can happen. Testing is not perfect, and some reactions are not IgE-mediated. If you had a convincing immediate reaction—especially a severe one—talk with your clinician about next steps even if the blood test is negative.
What is an IgE “class” on my report?
Some labs convert the numeric IgE value into a class (for example, Class 0 to Class 6) to describe the level of sensitization. The class can be a helpful shorthand, but the actual number and your clinical history are more important than the class label alone.
How soon after a reaction should I test?
You can usually test at any time because allergen-specific IgE tends to be relatively stable. If the exposure was very recent and you are early in the course of developing an allergy, your clinician may consider repeating the test later if suspicion remains high despite a negative result.
Should I retest celery IgE, and if so, when?
Retesting can be useful if your symptoms change, you have been strictly avoiding celery for a long period, or you are monitoring a known allergy over time with your clinician. A common interval is 6–12 months, but the right timing depends on your history and whether the result would change your plan.
Is this test the same as total IgE?
No. This is allergen-specific IgE to celery (F85). Total IgE measures your overall IgE level and can be elevated for many reasons; it does not tell you which specific foods or environmental allergens you are sensitized to.