Why is AST:ALT Ratio important?

This ratio helps distinguish between different causes of liver injury. A ratio greater than 2 strongly suggests alcoholic liver disease, while a ratio less than 1 is typical of non-alcoholic fatty liver disease (NAFLD) and viral hepatitis. The ratio increases as liver disease progresses to cirrhosis. It's a valuable tool for narrowing down the cause of elevated liver enzymes.

What are the symptoms of abnormal AST:ALT Ratio levels?

Abnormal ratios themselves don't cause symptoms, but underlying liver conditions may cause: fatigue, abdominal pain (especially upper right), nausea, jaundice (yellowing of skin/eyes), dark urine, and unexplained weight loss.

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AST:ALT Ratio

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The AST to ALT ratio (also known as De Ritis ratio) compares two liver enzymes to help differentiate between various types of liver disease and assess liver health.

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This ratio helps distinguish between different causes of liver injury
A ratio greater than 2 strongly suggests alcoholic liver disease, while a ratio less than 1 is typical of non-alcoholic fatty liver disease (NAFLD) and viral hepatitis
The ratio increases as liver disease progresses to cirrhosis
It's a valuable tool for narrowing down the cause of elevated liver enzymes

AST / ALT

The AST to ALT ratio (also known as De Ritis ratio) compares two liver enzymes to help differentiate between various types of liver disease and assess liver health

Abnormal ratios themselves don't cause symptoms, but underlying liver conditions may cause: fatigue, abdominal pain (especially upper right), nausea, jaundice (yellowing of skin/eyes), dark urine, and unexplained weight loss

High ratio (>2): Alcoholic liver disease, cirrhosis, muscle damage, heart attack. Ratio 1-2: Mixed or advanced liver disease.
Low ratio (<1): Non-alcoholic fatty liver disease (NAFLD), viral hepatitis, drug-induced liver injury.

This is a calculated biomarker derived from other test results in your panel. It provides additional clinical insights by combining multiple measurements into a single meaningful ratio or index.

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AST:ALT Ratio

About AST:ALT Ratio

How It's Calculated

Why AST:ALT Ratio Matters

Symptoms of AST:ALT Ratio

What Affects AST:ALT Ratio Levels

How it works: 4 easy steps

Choose your tests

Quick & convenient testing

Clear, personalized results

Optimize your health

Our Comprehensive Panels

Explore Other Tests

Basophils

Apolipoprotein B

Nitrite

Monocyte-to-Lymphocyte Ratio (MLR)

Our Customers Says

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