Allergen Specific M14 IgG (Epicoccum purpurascens) Biomarker Testing
It measures IgG antibodies to Epicoccum purpurascens mold to support exposure context, with convenient ordering and clear results through Vitals Vault.
With Vitals Vault, you have access to a comprehensive range of biomarker tests.

This test looks for IgG antibodies your immune system has made to a specific mold: Epicoccum purpurascens (often abbreviated as “Epicoccum”). Your result is not the same thing as a classic “allergy test,” which usually measures IgE.
People usually consider Epicoccum IgG testing when they are trying to connect symptoms with possible indoor mold exposure, compare environments (home vs. workplace), or document immune response patterns over time.
Because IgG can reflect exposure and immune recognition rather than immediate allergy, the most useful way to read this result is alongside your symptoms, your environment, and any related testing your clinician recommends.
Do I need a Allergen Specific M14 IgG Epicoccum Purpurascens test?
You might consider this test if you have ongoing, hard-to-pin-down symptoms that seem tied to certain buildings or seasons, such as persistent nasal congestion, post-nasal drip, cough, throat irritation, sinus pressure, headaches, or fatigue. Some people also pursue mold-related testing when they notice symptom flares after water damage, musty odors, visible mold, or HVAC problems.
This test can also be reasonable if you are comparing exposure risk between environments (for example, symptoms that improve when you travel or worsen at work), or if you are tracking whether a remediation or relocation plan is changing your immune response over time.
You may not need Epicoccum IgG if your main concern is immediate allergy symptoms like hives, wheezing right after exposure, or anaphylaxis risk. In those cases, IgE-based testing and an allergy-focused evaluation are usually a better fit.
Testing is most helpful when it supports clinician-directed care and an exposure plan, rather than being used as a standalone diagnosis.
This is typically a CLIA-certified laboratory blood test for allergen-specific IgG; results support clinical context and do not diagnose mold illness or allergy on their own.
Lab testing
Order Epicoccum purpurascens (M14) IgG testing
Schedule online, results typically within about a week
Clear reporting and optional clinician context
HSA/FSA eligible where applicable
Get this test with Vitals Vault
Vitals Vault lets you order Epicoccum purpurascens (M14) IgG testing without a separate doctor visit, and complete your blood draw through a national lab network.
After your result posts, you can use PocketMD to review what “low,” “in-range,” or “high” means for allergen-specific IgG, and to map next steps to your situation—such as whether it makes sense to add IgE testing, broaden to other molds, or focus on environmental assessment.
If you are already working with a clinician, you can bring your Vitals Vault report into that visit to support a more targeted conversation about symptoms, timing, and retesting.
- Order online and complete a standard blood draw
- PocketMD helps you interpret results in plain language
- Easy reordering if you are trending changes over time
Key benefits of Allergen Specific M14 IgG Epicoccum Purpurascens testing
- Helps you document immune recognition of Epicoccum mold as part of an exposure workup.
- Adds context when symptoms seem building-related or worsen in damp or musty environments.
- Supports before-and-after comparisons if you remediate, move, or change workplace exposure.
- Can be paired with IgE testing to separate immediate allergy patterns from IgG exposure patterns.
- May help narrow which mold targets to prioritize when broader panels feel too nonspecific.
- Gives your clinician a concrete data point to integrate with history, exam, and other labs.
- Creates a baseline you can trend over time instead of relying only on symptom memory.
What is Allergen Specific M14 IgG Epicoccum Purpurascens?
Allergen-specific IgG is a blood measurement of IgG antibodies directed at a particular substance (antigen). In this case, the antigen is Epicoccum purpurascens, a common environmental mold found outdoors and sometimes indoors, especially in damp areas or where organic material accumulates.
IgG antibodies are part of your adaptive immune system. A detectable IgG level can mean your immune system has encountered and responded to that mold at some point. That is why IgG is often discussed in the context of exposure and immune “memory,” not necessarily immediate allergic reactivity.
Your lab report will usually provide a numeric value and a lab-specific interpretation category. Because methods and cutoffs vary by laboratory, it is better to interpret your result using the reference information on your report and your clinical context rather than comparing numbers across different labs.
IgG vs. IgE: why the distinction matters
IgE is the antibody class most associated with classic, immediate allergy symptoms (sneezing fits, itchy eyes, hives, wheeze soon after exposure). IgG is more complicated: it can reflect exposure, immune recognition, and sometimes chronic or repeated contact. A high IgG does not automatically mean you are “allergic,” and a low IgG does not rule out sensitivity or irritation from a moldy environment.
Where Epicoccum shows up
Epicoccum is commonly found in soil, decaying plant material, and outdoor air. Indoors, it can be present when moisture problems allow mold growth on surfaces, in dust, or around HVAC systems. If your symptoms track with specific buildings, this test can be one piece of a broader exposure puzzle.
What do my Allergen Specific M14 IgG Epicoccum Purpurascens results mean?
Low Epicoccum purpurascens IgG
A low or negative result often means there is no strong IgG signal to Epicoccum at the time of testing. This can happen if you have had little exposure, if exposure was remote in time, or if your immune system simply does not produce a measurable IgG response to this specific mold. If your symptoms strongly suggest mold-related triggers, a low result does not rule out other molds, non-allergic irritation, or an IgE-mediated allergy pattern.
In-range / expected Epicoccum purpurascens IgG
An in-range result generally suggests no unusual elevation compared with the lab’s reference expectations. For many people, this aligns with either minimal exposure or a typical background level of immune recognition. If you are testing to track change, “in-range” can still be meaningful as a baseline to compare against future results using the same lab method.
High Epicoccum purpurascens IgG
A high result means your immune system shows a stronger IgG response to Epicoccum than the lab’s reference range. This is often interpreted as evidence of exposure and immune recognition, especially when it matches your timeline (for example, symptoms that worsen in a specific environment). It does not prove that Epicoccum is the sole cause of symptoms, and it does not by itself diagnose mold allergy or mold-related illness. Many clinicians use a high IgG as a prompt to look more closely at environment, co-exposures, and whether additional testing (including IgE) is appropriate.
Factors that influence Epicoccum purpurascens IgG
Recent or repeated exposure can raise IgG, while reduced exposure over time may allow levels to drift down. Your immune status matters too: immunosuppressive medications, certain chronic illnesses, or immune deficiencies can blunt antibody responses. Cross-reactivity can occur, meaning antibodies may partially recognize related molds, which can complicate “one mold, one symptom” conclusions. Finally, different labs and assay methods use different cutoffs, so trending is most reliable when you repeat testing with the same methodology.
What’s included
- Allergen Spec.(M14)Igg Epicoccum Purpurascens*
Frequently Asked Questions
Is Epicoccum purpurascens IgG an allergy test?
It measures IgG antibodies, which are not the primary marker of immediate-type allergy. If you are evaluating classic allergy symptoms, allergen-specific IgE testing is usually the more direct tool. IgG is more often used to add context about exposure and immune recognition.
Do I need to fast for an Epicoccum IgG blood test?
Fasting is usually not required for allergen-specific IgG testing. If you are ordering other labs at the same time, follow the fasting instructions for the full set of tests on your order.
What does a high mold IgG level mean?
A high IgG suggests your immune system has mounted a stronger antibody response to that mold than the lab’s reference range. It can support an exposure narrative, especially if timing and symptoms fit, but it does not diagnose mold allergy or prove causation by itself.
Can I have symptoms with a negative Epicoccum IgG?
Yes. Symptoms can come from other molds, dust mites, pollen, irritants, infections, asthma, reflux, or non-allergic inflammation. A negative IgG also does not rule out an IgE-mediated allergy pattern, which is a different antibody class.
How often should I retest mold IgG?
Retesting is most useful when you are tracking a specific change, such as remediation, relocation, or a clear shift in exposure. Many people wait several weeks to a few months so the immune signal has time to reflect the new environment, but the right interval depends on your situation and your clinician’s plan.
Should I test IgG or IgE for mold?
If your symptoms are immediate and allergy-like (sneezing, itching, wheeze soon after exposure), IgE is often the better starting point. If your goal is to document exposure patterns or add context to chronic, environment-linked symptoms, IgG may be helpful. In some cases, both are used because they answer different questions.