Allergen Specific IgE Lombardy Poplar (Poplar Pollen) Blood Biomarker Testing
It measures IgE sensitization to Lombardy poplar pollen to support allergy evaluation, with easy ordering and Quest-based lab collection via Vitals Vault.
With Vitals Vault, you have access to a comprehensive range of biomarker tests.
If your symptoms flare up in spring or early summer—sneezing, itchy eyes, runny nose, or asthma-like tightness—you may wonder whether a specific tree pollen is part of the problem. The Allergen Specific IgE Lombardy Poplar test looks for IgE antibodies in your blood that react to Lombardy poplar pollen.
This is a sensitization test, which means it helps identify whether your immune system has learned to recognize poplar pollen as an allergen. It does not prove that poplar is the only cause of your symptoms, but it can clarify what to avoid, what to treat, and what to test next.
Because pollen allergies often overlap (and tree pollens can cross-react), this single result is most useful when you interpret it alongside your symptom pattern, seasonality, and other allergy tests.
Do I need a Allergen Specific IgE Lombardy Poplar test?
You may consider this test if you get predictable seasonal symptoms such as sneezing, congestion, post-nasal drip, itchy or watery eyes, cough, or wheeze—especially if they worsen outdoors, on windy days, or after yard work.
It can also be helpful if you have allergic asthma or eczema that flares during tree pollen season, or if you are trying to distinguish “a cold that won’t go away” from allergy-driven inflammation.
A Lombardy poplar–specific IgE result is most actionable when you already suspect tree pollen exposure or you live in an area where poplar trees are common. If your symptoms are year-round, you may get more value from a broader inhalant allergy panel rather than a single tree allergen.
Testing supports clinician-directed care and shared decision-making. Your result should be interpreted in context rather than used as a standalone diagnosis.
This is a laboratory-developed or FDA-cleared immunoassay performed in a CLIA-certified lab; results indicate sensitization risk and are not, by themselves, a diagnosis of clinical allergy.
Lab testing
Order labs to measure Allergen Specific IgE Lombardy Poplar
from $87.17 at Quest Diagnostics
About 1 week
Schedule online — results typically within a week
Clear next steps
Guidance included, with follow-up care available
HSA / FSA
Eligible for pre-tax health spending accounts
Get this test with Vitals Vault
With Vitals Vault, you can order Lombardy poplar–specific IgE testing without a referral and complete your blood draw through a nationwide lab network. This is useful when you want a clear, documented result to bring to your clinician or to guide next-step testing.
After your results post, PocketMD can help you make sense of what “low,” “in-range,” or “high” means for allergen-specific IgE, how this fits your symptom timing, and which companion tests are commonly paired (such as total IgE or other tree pollens).
If your symptoms change over time, you can also use repeat testing strategically—for example, before and after a season, or after major exposure changes—so you can track patterns rather than guessing.
- Order online and schedule a local blood draw
- Clear, shareable results for clinician follow-up
- PocketMD guidance for next steps and retest timing
Key benefits of Allergen Specific IgE Lombardy Poplar testing
- Helps identify whether your immune system is sensitized to Lombardy poplar pollen.
- Supports separating seasonal allergy patterns from infections or non-allergic rhinitis.
- Guides practical avoidance steps during peak pollen periods when symptoms spike.
- Helps prioritize which additional tree pollens to test when cross-reactivity is likely.
- Adds context for asthma, cough, or sinus symptoms that worsen outdoors or seasonally.
- Supports treatment planning discussions, including whether allergy referral makes sense.
- Creates a baseline you can compare over time if symptoms or exposures change.
What is Allergen Specific IgE Lombardy Poplar?
Allergen-specific IgE is a type of antibody your immune system can produce when it becomes sensitized to a particular allergen. In this test, the lab measures IgE antibodies that bind to proteins from Lombardy poplar pollen.
If you are sensitized, your immune system is more likely to trigger an immediate-type allergic response when you inhale that pollen. This can contribute to symptoms like sneezing, congestion, itchy eyes, and in some people, asthma symptoms.
A key point is that sensitization and symptoms are related but not identical. You can have a positive IgE result and minimal symptoms (especially with low exposure), or you can have symptoms driven by other allergens even if poplar IgE is negative. Your history—when symptoms happen, where you are, and what improves them—matters as much as the number.
How this differs from skin testing
Skin prick testing looks for an immediate skin reaction to an allergen extract, while this blood test measures circulating IgE antibodies. Blood testing can be useful if you cannot stop antihistamines, have certain skin conditions, or prefer a single blood draw for multiple allergens. Both approaches can be clinically valid, and your clinician may choose one based on your situation.
Why single-allergen testing is sometimes ordered
A targeted test can be helpful when your symptoms line up with a specific season or exposure and you want to confirm or rule out one suspected trigger. If you are unsure what is driving symptoms, a broader inhalant panel may be more efficient than ordering many single allergens one by one.
What do my Allergen Specific IgE Lombardy Poplar results mean?
Low or undetectable Lombardy poplar–specific IgE
A low or undetectable result suggests you are unlikely to be sensitized to Lombardy poplar pollen. If you still have strong seasonal symptoms, another tree pollen, grass pollen, weed pollen, dust mites, mold, or pet dander may be a better match. Timing matters too—if you tested far from the season or after major exposure changes, your clinician may still consider broader testing based on your history.
In-range results (what “normal” usually means here)
For allergen-specific IgE, “normal” typically means the lab did not detect meaningful sensitization to this specific allergen. That does not rule out allergies in general; it only speaks to Lombardy poplar. If your symptoms are consistent with pollen allergy, the next step is often testing additional relevant pollens and comparing results to your symptom calendar.
High Lombardy poplar–specific IgE
A higher result means your immune system is sensitized to Lombardy poplar pollen, and exposure may contribute to symptoms during the poplar pollen season. The higher the value (or class), the more likely it is to be clinically relevant, but the number alone cannot predict how severe your symptoms will be. Use this result alongside your real-world pattern—when symptoms start, how they respond to antihistamines or nasal steroids, and whether outdoor exposure reliably triggers flares.
Factors that influence allergen-specific IgE results
Results can be influenced by cross-reactivity among related tree pollens, meaning you may test positive to multiple trees even if one is the main trigger. Age, overall allergic tendency (atopy), and total IgE levels can affect how easily you produce detectable IgE. Recent or ongoing high exposure during pollen season can align with more obvious symptoms, while low exposure may make a positive result feel “silent.” Immunotherapy and long-term changes in exposure can also shift results over time, so retesting should be planned rather than routine.
What’s included
- Allergen Specific Ige Lombardy Poplar
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Frequently Asked Questions
Do I need to fast for a Lombardy poplar IgE blood test?
Fasting is not usually required for allergen-specific IgE testing. If you are combining this with other labs (like lipids or glucose), follow the instructions for the full order.
Can antihistamines affect allergen-specific IgE blood test results?
Antihistamines typically do not change blood IgE measurements, which is one reason blood testing is sometimes chosen over skin testing. However, medications can change how you feel, so symptom timing and treatment response still matter for interpretation.
What does an IgE “class” mean on my report?
Some labs report allergen-specific IgE as both a number and a class category (for example, Class 0 to Class 6). The class is a simplified way to group the quantitative value, but it is still best interpreted with your symptom history and exposure timing.
If my poplar IgE is positive, does that prove I’m allergic to poplar pollen?
A positive result shows sensitization, meaning your immune system recognizes poplar pollen. Clinical allergy is diagnosed when sensitization matches real symptoms with exposure, so your clinician will weigh your seasonality, triggers, and response to treatment.
When should I retest allergen-specific IgE?
Retesting is most useful when something changes—new or worsening seasonal symptoms, a move to a different region, starting or completing immunotherapy, or when you are mapping triggers over multiple seasons. Many people do not need frequent repeat testing unless it will change the plan.
Should I test other tree pollens if this is negative?
Often, yes—especially if your symptoms strongly suggest spring tree pollen allergy. Tree pollens can vary by region and season, and cross-reactivity can make a broader tree panel more informative than a single allergen.