
List of blood tests for preventive health tracking: core labs, longevity add-ons, testing cadence, and prep tips to track trends over time.
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This article provides a comprehensive list of blood tests essential for preventive health tracking, focusing on how to use them to monitor key markers over time. It covers foundational panels such as CBC, CMP, and glucose tests, as well as advanced markers for cardiometabolic risk, liver function, kidney health, and nutrient status. Designed for those interested in proactive health management, the post also offers guidance on testing frequency, preparation, and interpreting results effectively with a preventive mindset.
Preventive health tracking is less about chasing “perfect” numbers and more about building an early-warning system you can actually act on. The right lab markers help you spot silent trends (insulin resistance, inflammation, liver workload, nutrient depletion) months or years before symptoms show up.
Below is a practical list of blood tests to consider for preventive health tracking, plus how to use them as a repeatable system.
A single lab value is a snapshot. Preventive tracking works when you treat labs like a dashboard:
If you’re choosing tests for the first time, aim for a core set that covers the major longevity domains: cardiometabolic risk, liver and kidney function, inflammation, blood health, thyroid, and key nutrients.

These are the “foundation” labs that make it easier to interpret everything else.
A CBC is a broad view of oxygen-carrying capacity, immune status, and clotting components.
What it helps track:
Common components include WBC count, hemoglobin, hematocrit, MCV, RDW, and platelets.
A CMP is one of the highest-value preventive panels because it touches liver, kidney, electrolytes, and protein status.
What it helps track:
These are core markers for metabolic health.
For screening context, the USPSTF recommends screening adults 35 to 70 with overweight or obesity for prediabetes and type 2 diabetes.
A standard lipid panel typically includes total cholesterol, HDL-C, LDL-C, and triglycerides. It’s useful, but for preventive tracking, many people add more specific risk markers.
If your goal is proactive prevention, these tend to provide more actionable signal than “basic” labs alone.
ApoB is a proxy for the number of atherogenic particles that can enter the artery wall. Many preventive clinicians use ApoB to refine cardiovascular risk beyond LDL-C.
Related Vitals Vault resource: Apolipoprotein B
Lp(a) is largely genetic and is often measured at least once in adulthood to identify hidden inherited risk.
Related Vitals Vault resource: Lipoprotein(a)
hs-CRP is a widely used marker of systemic inflammation and is often tracked alongside lipids and glucose for cardiometabolic risk.
Related Vitals Vault resource: hs-CRP
Fasting insulin can help detect early insulin resistance even when glucose and HbA1c still look “normal.” It is best interpreted in context rather than alone.
Your liver sits at the intersection of alcohol exposure, fatty liver risk, medication metabolism, and metabolic health. These labs are useful for both prevention and performance.
ALT and AST are enzymes that can rise with liver stress, muscle injury, medications, and other conditions. Trends matter.
Vitals Vault resource if you want deeper interpretation: AST
GGT is often discussed as a sensitive marker of liver workload and oxidative stress exposure, particularly in the context of alcohol use and fatty liver risk.
Vitals Vault resource: GGT
These can help contextualize liver and bile flow patterns (especially when interpreted with GGT, ALT, and AST).
Creatinine is a foundational kidney marker. eGFR is typically calculated from creatinine (and sometimes includes age and sex). Interpretation should consider muscle mass, hydration, and recent intense exercise.
Electrolytes can shift with hydration, diet, medications, adrenal issues, kidney function changes, and endurance training load.
Iron markers are a frequent source of confusion because inflammation, infection, and training stress can distort interpretation.
Ferritin reflects iron storage but is also an acute phase reactant, meaning it can rise with inflammation.
Vitals Vault resource: Ferritin
These help contextualize ferritin and can clarify whether you’re dealing with iron deficiency, iron overload patterns, or inflammation-related shifts.
These are popular in preventive programs because they are modifiable, and deficiencies can quietly undermine energy, mood, immune function, and training adaptation.
Vitamin D status is common to track because it is influenced by latitude, season, skin exposure, and supplementation.
Vitals Vault resource: Vitamin D, 25-Oh, Total
B12 and folate status matters for red blood cell formation and neurologic function. If B12 is borderline, many clinicians pair it with functional markers.
Homocysteine can function as a “metabolic stress” marker influenced by B vitamins, genetics, thyroid status, kidney function, and lifestyle.
Vitals Vault resource: Homocysteine
Thyroid function affects cholesterol handling, heart rate, body temperature, and energy. For preventive tracking, a common starting point is:
Autoimmune thyroid risk is often evaluated with thyroid antibodies (TPO and Tg antibodies) when clinically appropriate.
Hormone testing can be helpful when it’s tied to a specific question (fatigue, libido changes, sleep disruption, fertility planning, recovery issues). In preventive programs, common blood tests include:
Because hormones follow daily rhythms and respond to sleep, alcohol, training, and calorie intake, consistency in timing is crucial for trend tracking.
The ideal frequency depends on risk level and whether you’re actively changing something.
If you’re using labs to guide decisions, consistency matters more than chasing ultra-frequent testing.
A few controllable variables can make your results far more comparable over time:
Also document what changed before a draw (illness, travel, new supplements, poor sleep week) so you can interpret outliers with context.
A list is useful, but the leverage comes from:
Vitals Vault is designed for that workflow: you can order comprehensive panels (100 to 160+ biomarkers) without a doctor referral, get clinician-reviewed insights in days, and follow longevity protocols tailored to your biology. Plans start at $99, are HSA/FSA eligible nationwide, and include a guarantee of at least 3 actionable insights or your money back.
If you want help interpreting patterns across markers (instead of guessing at isolated flags), you can also read the Vitals Vault guide to reading blood test results or explore the testing options at Vitals Vault.
This article is for educational purposes and is not medical advice. If you have symptoms, abnormal results, or chronic conditions, review your testing plan and results with a licensed clinician.
Tracking the right blood tests consistently creates a valuable early-warning system for identifying health trends before symptoms arise. By focusing on core and advanced labs, along with thoughtful retesting and contextual interpretation, you can make informed decisions about nutrition, lifestyle, and clinical care. Consider establishing your baseline and following a repeatable testing routine to optimize long-term health and address individual risk factors proactively.