An on-demand cream with L-arginine and oxytocin, applied 15 to 30 minutes before sex. Made for you.
$53.17/moBilled $319 every 180 days
Medication is charged only if your clinician prescribes it.
Start with a $20 clinician review
43%
of US women report a sexual problem (age-adjusted), in a survey of 31,581 women
Source: Shifren JL, et al. Obstet Gynecol 2008;112(5):970-8 (PRESIDE survey)12%
report a sexual problem that also causes them personal distress
Source: Shifren JL, et al. Obstet Gynecol 2008;112(5):970-8 (PRESIDE survey)14.8%
of women aged 45 to 64 report a distressing sexual problem, the highest of any age group
Source: Shifren JL, et al. Obstet Gynecol 2008;112(5):970-8 (PRESIDE survey)These figures show how common the concern is. They are not results for Euphoria O, which is compounded, not FDA approved, and has not been tested in clinical trials. Studies of oxytocin on its own have been small and have not shown a clear benefit for women's sexual function. Individual results vary.
A prescription cream made for you and ready when you are, reviewed by a clinician first, with a plan to try something else if it is not right.
Clinician review of your history
A US-licensed clinician checks your health, medicines and goals, and prescribes only if it fits.
Your cream, compounded for you
Oxytocin, L-arginine and niacin cream from a licensed US pharmacy, in a 90 or 180-day supply.
Free, discreet shipping
Plain packaging to your door, 2 to 5 business days after approval.
Your care team on message
Tell us how it goes, and your clinician can adjust the plan or suggest other options.
Free lab panel at month 3
Biological Age Reveal, as a progress check.
“What if this is not the right fix?”
A route to vaginal estrogen
If dryness is the real issue, the same clinician can prescribe vaginal estradiol cream.
“I want this to stay private.”
Nothing on the box gives it away
It arrives in plain packaging, with no pharmacy counter conversation.
Biological Age Reveal
Euphoria O is a compounded cream with three ingredients. Oxytocin is a hormone involved in bonding and arousal, L-arginine is the amino acid your body uses to make nitric oxide, a signal that relaxes blood vessels, and niacin (vitamin B3) widens skin blood vessels and commonly causes a warm flush.
You apply a measured 0.25 mL where you want it, 15 to 30 minutes before sex, once a day at most. This exact combination has not been tested in clinical trials, so we describe how it is used and make no promise about the result.
Apply 15 to 30 minutes before. It works where you apply it. Use it no more than once a day.
What you would like to change, plus your health history and any medicines. About 5 minutes.
About 5 minutes
They confirm the cream fits you, and prescribe only if it does.
Reviewed within 24 hours
If prescribed, your compounded cream comes from a licensed US pharmacy, with nothing on the box that says what is inside.
Ships in 2 to 5 business days
Apply 0.25 mL to the clitoral and vulvar area 15 to 30 minutes before sex, no more than once a day.
15 to 30 minutes before
Your care team can adjust the plan or suggest other options, including treatment for dryness.
Your clinician reviews your history, medicines and whether you are pregnant or breastfeeding.
Apply 0.25 mL 15 to 30 minutes before sex. A mild warm feeling is expected from the niacin.
Wash it off and message your care team.
Tell us how it goes, and your care team can adjust the plan or suggest other options, including treatment for dryness.
Three things you can do alongside your treatment.
Your body will not switch to arousal while it is on alert. Slow breathing, a daily outdoor walk and time without screens settle your stress response, and cortisol is the signal to watch.
Poor sleep dulls mood and desire, and good relationships and touch lower the stress that gets in the way. A regular bedtime, a cool dark room and protected time together do more than any cream.
Low free testosterone, low DHEA-S, low estradiol, thyroid problems and some medicines can all lower desire and comfort. A hormone panel and TSH can show which of these applies to you.
| Feature | Euphoria O | Over-the-counter lubricant | Vaginal estradiol cream |
|---|---|---|---|
| What it is for | On-demand use before sex | Reduces friction during sex | Treats the tissue changes behind menopausal dryness and painful sex |
| Prescription | Yes, clinician reviewed | No | Yes, clinician reviewed |
| Clinical evidence | This combination has not been tested in trials | Well established for friction | Many randomized trials show relief of dryness and painful sex |
| Routine | As needed, no more than once a day | As needed | Nightly for 2 weeks, then up to 3 times a week |
| Best for | Women who want an on-demand option and accept limited evidence | Friction and mild dryness | Dryness, burning or pain after menopause |
If dryness or pain after menopause is the main issue, ask your clinician about vaginal estrogen first.
Apply 0.25 mL to the clitoral and vulvar area 15 to 30 minutes before sexual activity, no more than once a day.
This is a compounded cream. Its ingredients have no FDA approved product in this combination or at this dose for arousal, so there is no FDA reviewed safety label and no established side effect rate. What follows comes from your prescribing clinician rather than from a label.
Tell your care team straight away if you get a rash, swelling or burning where you applied it, a headache that will not settle, or dizziness.
This is not a complete list of side effects. Message your care team about any symptom that worries you. What we dispense is a compounded preparation made by a licensed US pharmacy. Compounded medications are not approved by the FDA for safety, efficacy or quality.
Oxytocin, L-arginine hydrochloride and niacin in a cream base, compounded by a licensed US pharmacy for you. Niacin commonly causes a brief feeling of warmth where it touches the skin.
No. This combination has not been tested in clinical trials and is not FDA approved. Small studies of oxytocin on its own have not shown a clear benefit for women's sexual function, so we describe how to use the cream and do not promise a result. Your clinician can discuss options that have more evidence.
Apply 0.25 mL to the clitoral and vulvar area 15 to 30 minutes before sex, no more than once a day.
A mild warm feeling is expected because of the niacin. Wash it off and message your care team if you get burning, a rash, swelling or irritation that does not settle.
It can. Let it absorb first, and wash it off if your partner is sensitive.
Ask your care team about compatibility with your products, because creams can affect some materials.
Do not use it if you are pregnant or breastfeeding. Tell your clinician about every medicine you take and any history of allergic reactions to creams.
Vaginal dryness after menopause often responds to vaginal estrogen, which has far more evidence behind it. Your clinician can review whether that fits, and the two can be discussed together.
180-day supply · $53.17/mo · Billed $319 every 180 days
