
Tretinoin + Niacinamide Cream
From $1.28/day

Your skin. Your everyday.
Make space for a simpler skin-care routine, guided by your concerns and your goals.

From $1.28/day
You’re far from the only one. A US-licensed clinician looks at what you’re noticing and whether treatment fits you.


50 women
in a 12-week trial where 5% niacinamide reduced fine lines, spots and blotchiness
Source: Bissett et al., Dermatol Surg 20053-4 months
before most people notice effects of tretinoin; up to 6 months for some
Source: Renova label (FDA)SPF daily
sunscreen and sun protection are part of tretinoin use, per its FDA label
Source: Renova label (FDA)Thoughtful care for skin concerns, with room for the life you want to live.

A routine you can understand and come back to.

Small habits that belong in your everyday.

For plans, conversations, and moments beyond the mirror.
Three things that matter alongside treatment.
A gentle cleanser and a daily moisturizer keep the barrier intact, which is what tretinoin tests in the first weeks. A stronger barrier means fewer dropouts.
Stress, gut health and the immune system all feed into skin. A food pattern built on anti-inflammatory foods, steady sleep and a stress outlet give the cream a better starting point.
Sun exposure is the main driver of photoaging and makes retinoid-treated skin burn more easily. A daily broad-spectrum sunscreen and a hat protect the progress you are building.
Tell your clinician about your skin concerns, current products, and health history. Include any pregnancy plans before discussing prescription options.

Step 1
A few minutes

Step 2
Within 24 hours

Step 3
2–5 business days

Step 4
Ongoing

Your clinician reviews your concerns, skin-care routine, and health history before deciding whether a prescription fits. Availability alone does not mean a treatment is right for every person.
Ask your clinician how to introduce it and which other products to use. Retinoids can irritate skin; sun protection is important. Contact your care team if your skin becomes painful or irritated.
Tell your clinician before starting treatment. Retinoids should not be used during pregnancy. Ask your clinician about suitable options when planning pregnancy or breastfeeding.
No. A licensed clinician reviews your information and prescribes only when appropriate. You may be advised to seek another form of care.
A $20 clinician review, refunded if you’re not prescribed. Each plan shows its lowest rate with the real bill, and you can cancel anytime.
A US-licensed clinician reviews within 24 hours, and approved orders ship free in 2 to 5 business days.
Your treatment is reviewed and prescribed by US-licensed clinicians in our network.

Dermatology
Board certified dermatologist and Associate Professor of Dermatology at Duke University School of Medicine. Specializes in skin cancer and dermato-oncology.

Women's hormone health
Board certified in obstetrics and gynecology and a Menopause Society Certified Practitioner. Works with members on perimenopause, menopause and hormone therapy.

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