Skip to content
Vitals Vault
Men
Hormone OptimizationWeight ManagementSexual HealthHair RestorationLongevity & WellnessThyroidSupplementsSkin CareView all men’s care
Women
Hormone & Midlife CareWeight ManagementSexual WellnessHair RestorationLongevity & WellnessThyroidSupplementsSkin CareView all women’s care
PocketMDHow it worksLabs
Log inExplore treatments
Woman seated outdoors holding a yoga mat and looking toward the sunlight

Menopause treatment

Still you. More at ease.

Care for the changes you feel. More room for the life you love.

Explore treatmentsTake the quiz
  • US clinicians
  • Licensed pharmacy
  • LegitScript
  • 4.5 on Google
  • Review fee refunded
  • Free discreet shipping

Start or switch your treatment this season. Your lab panel is on us.

Nov 1 to Jan 31. Given at your 3-month mark.

Find your menopause care.

Free lab panel at month 3Estradiol 1.1 mg capsules bottle

Estradiol Oral Capsule

Capsule · 1.1 mg

From $1.94/day

Billed $349 every 180 days

Get startedLearn more
Free lab panel at month 3Micronized progesterone capsules bottle

Progesterone Capsules

Capsule · 100 mg / 200 mg

From $1.94/day

Billed $349 every 180 days

Get startedLearn more
Free lab panel at month 3Estradiol vaginal cream tube

Estradiol Vaginal Cream

For vaginal dryness

Vaginal cream · 0.01% (0.1 mg/g)

From $1.19/day

Billed $199 every 168 days

Get startedLearn more

Free shipping. HSA/FSA eligible. Prescribed only if appropriate.

Sound familiar?

You’re far from the only one. A US-licensed clinician looks at what you’re noticing and whether treatment fits you.

  • Hot flashes
  • Night sweats
  • Waking at 3 a.m.
  • Brain fog
  • Mood swings
  • Vaginal dryness
  • Painful sex
  • Irregular periods
  • Low energy
  • Joint aches
  • Weight creeping up
  • Lower desire
Estradiol 1.1 mg capsules bottle

Estradiol Oral Capsule

Capsule · 1.1 mg

From $1.94/day

See Estradiol Oral Capsule
A couple out cycling by the sea

Up to 80%

of women get hot flashes or night sweats

Source: Avis et al., Obstet Gynecol Clin North Am 2018
  • 7.4 years

    is how long frequent hot flashes last, at the median

    Source: Avis et al., Obstet Gynecol Clin North Am 2018
  • About 1 in 2

    postmenopausal women have vaginal or urinary symptoms

    Source: GSM meta-analysis, Front Med 2022

Start without the risk

  • $20 review refunded if not prescribed
  • Cancel anytime
  • Full refund before your blood draw

For your days. Your nights. Your sense of you.

Explore care for hot flashes, disrupted nights, and changes in intimate comfort.

A Middle Eastern woman in her late 30s with long dark hair cooling off by an open window, at ease

More ease in your everyday

For days that feel less interrupted by hot flashes.

Woman enjoying a quiet morning by her kitchen window

Make room for restful nights

For fewer night-sweat interruptions and more settled rest.

A couple sharing a close moment at home

Comfort in the moments that matter

For relief from vaginal dryness and more comfortable closeness.

What changes the result

Three things that matter alongside treatment.

  1. 01

    Keep the night cool and regular

    Night sweats are the sleep thief. A bedroom around 65 to 68 degrees Fahrenheit, a dark room, the same bed and wake times, and screens off two hours before bed help your body cool down while estradiol quiets the flashes.

  2. 02

    Turn down the stress signal

    Estradiol helps blunt your cortisol response to stress, so the drop at menopause can make stress feel louder. Slow breathing, a daily outdoor walk and a steady morning routine lower the load on your stress axis.

  3. 03

    Protect bone, lipids and vitamin D

    Lifting weights twice a week, protein at every meal, calcium and vitamin D keep bone and muscle strong. Because oral estrogen can raise triglycerides, we suggest a lipid panel, fasting glucose, blood pressure and vitamin D check, and repeat them as your clinician advises.

Your comfort, over time.

Start with what’s changed and what matters to you. Your clinician helps you choose a plan, so you can take the first step toward feeling more comfortable.

With the right systemic hormone therapy, hot flashes and night sweats may begin to ease. Fewer interruptions can make everyday life feel a little more like yours again.

As your treatment settles in, you may feel more comfortable in your day-to-day life and more at ease with intimacy. Check in with your clinician to fine-tune what’s working for you.

When your plan is helping, keep making space for the moments you enjoy. Continued treatment can help maintain symptom relief, with adjustments when you need them.

Keep the comfort going. Review your symptoms, benefits, and health with your clinician so your care continues to fit this chapter of your life.

DISCLAIMER

These are possible experiences with clinician-prescribed estrogen therapy, not a promise or a timeline for every product above. Systemic estrogen treats hot flashes and night sweats; vaginal estrogen targets local symptoms. Later milestones describe ongoing support, not steadily increasing effects. Results and timing vary. Compounded products are not FDA-approved.

Research:Hormone therapyEarly changes and follow-upVaginal symptom reliefCompounded therapies

From goal to doorstep in four steps

Woman completing a private online health intake at home

Step 1

Tell us your goals

A few minutes

Step 1

Tell us your goals

A short, private intake about your health and what you want to improve.

A few minutes

A man with gray hair in a cream knit sweater relaxing on a sunny terrace beside olive trees, smiling during a phone call.

Step 2

A clinician reviews

Within 24 hours

Step 2

A clinician reviews

A licensed provider reviews your info and labs, if needed, and builds your plan.

Within 24 hours

Discreet treatment delivery

Step 3

Delivered to your door

2–5 business days

Step 3

Delivered to your door

Approved treatment ships free in plain, discreet packaging.

2–5 business days

Woman checking her ongoing care plan on her phone at home

Step 4

Ongoing care

Ongoing

Step 4

Ongoing care

Message your PocketMD provider anytime; we adjust your plan as you progress.

Ongoing

Explore treatments

Your questions, answered.

Messaging the care team from home
Can I get help before my periods stop?+

You can seek care during perimenopause, before periods stop completely. Your clinician reviews your symptoms, cycle changes, health history, and goals. Testing is recommended when it would help clarify your care.

How is vaginal estrogen different from tablets or patches?+

Tablets and patches deliver estrogen throughout the body and can help hot flashes and night sweats. Vaginal estrogen is used for local symptoms such as dryness and irritation. Your clinician helps match the treatment to what you’re experiencing.

Will I need progesterone with estrogen?+

If you have a uterus and use systemic estrogen, you will generally need a progestogen to protect the uterine lining. Progesterone cream should not be relied on for this protection. Your clinician will discuss an appropriate regimen and review your personal risks.

Will I automatically get a prescription?+

No. A licensed clinician reviews your history and decides whether treatment is appropriate. Tell them about unexplained bleeding, any cancer or clotting history, your medications, and whether pregnancy is possible. Some catalog options are coming soon; each product page shows its status.

What does it cost to start?+

A $20 clinician review, refunded if you’re not prescribed. Each plan shows its lowest rate with the real bill, and you can cancel anytime.

How fast is it?+

A US-licensed clinician reviews within 24 hours, and approved orders ship free in 2 to 5 business days.

The clinicians behind your care

Your treatment is reviewed and prescribed by US-licensed clinicians in our network.

Diana Kumar, MD, FACOG

Diana Kumar, MD, FACOG

Women's hormone health

Board certified in obstetrics and gynecology and a Menopause Society Certified Practitioner. Works with members on perimenopause, menopause and hormone therapy.

William Blackwell, MD

William Blackwell, MD

Weight and metabolic health

Board certified in emergency medicine and practicing telehealth since 2018. Focuses on weight management and metabolic health.

Shamail Tariq, MD

Shamail Tariq, MD

Cardiometabolic health

Board certified in cardiovascular disease and interventional cardiology. Focuses on preventive cardiology, blood pressure and cholesterol.

Explore other goals

Woman smiling while jogging outdoors beside a landscaped walkway

Your pace. Your progress.

Weight care that makes room for your health, your routines, and you.

Explore lose weight
Woman leaning against her partner on a quiet lakeside pier

More connection. More you.

Your pleasure matters. Find private, personal care for desire and arousal.

Explore improve sexual function
Woman with wavy brown hair smiling on a garden terrace

Your hair. Still you.

Make room for fuller-looking hair. Find personal care that fits your everyday.

Explore improve appearance
Two women sharing tea and conversation at an outdoor picnic table

A start-low, build-up NAD+ injection with clinician oversight.

The human evidence is still early.

Explore live longer & better
Woman smiling in a white blouse against a warm stone wall

Keep your thyroid levels steady.

Levothyroxine from a US pharmacy, dosed from your TSH and free T4.

Explore manage thyroid
Woman holding a glass of water with supplement bottles on the table

Low B12, fixed at the source.

A weekly methylcobalamin injection that skips your gut.

Explore supplements
Woman gently touching her cheek in a skincare studio portrait

Your skin. Your everyday.

Make space for a simpler skin-care routine, guided by your concerns and your goals.

Explore clearer skin

Your body is changing. Your care can, too.

Hot flashes. Restless nights. Comfort that feels different. You don’t have to just put up with it.

Talk with a clinician who listens, and explore menopause care built around you.

Explore treatments

Stay on top of your health.

Join for practical tips, new treatments, and member-only offers.

Vitals Vault

Personalized men's & women's care, built on your labs.

Men’s Care

Hormone OptimizationWeight ManagementSexual HealthHair RestorationLongevity & Wellness

Women’s Care

Hormone & Midlife CareWeight ManagementSexual WellnessHair RestorationLongevity & Wellness

Company

AboutHow it worksExplore LabsSupportSign in

Legal

PrivacyTerms

Prescription products require an online consultation with a licensed clinician who will determine if a prescription is appropriate. Individual results vary. Not for use in a medical emergency. © Vitals Vault

Verify Approval for www.vitalsvault.com

From $1.19/day · $20 clinician review.

Billed $199 every 168 days. $20 review refunded if not prescribed. Cancel anytime.

See treatments