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Prescription skin care for men

Your skin. Your everyday.

Clearer, smoother skin with one simple nightly step, prescribed for you.

Explore treatmentsLearn about care
  • US clinicians
  • Licensed pharmacy
  • LegitScript
  • 4.5 on Google
  • Review fee refunded
  • Free discreet shipping

Start or switch your treatment this season. Your lab panel is on us.

Nov 1 to Jan 31. Given at your 3-month mark.

Find your skin-care treatment.

Free lab panel at month 3Tretinoin and niacinamide face cream tube

Tretinoin + Niacinamide Cream

Topical cream · Tretinoin 0.05% with niacinamide · 30 g

From $1.28/day

Billed $229 every 180 days

Get startedLearn more

Prescribed only if appropriate. Compounded medications are not FDA-approved for safety, effectiveness, or quality.

Sound familiar?

You’re far from the only one. A US-licensed clinician looks at what you’re noticing and whether treatment fits you.

  • Rough, uneven texture
  • Clogged pores
  • Recurring breakouts
  • Dark marks after spots
  • Dull, tired-looking skin
  • Fine lines appearing
  • Sun-damaged skin
  • Uneven skin tone
  • Oily patches
Tretinoin and niacinamide face cream tube

Tretinoin + Niacinamide Cream

Topical cream · Tretinoin 0.05% with niacinamide · 30 g

From $1.28/day

See Tretinoin + Niacinamide Cream
A white man in his early 50s with a salt-and-pepper beard caring for his skin in morning light

35 trials

In 33,472 people, single topical agents including tretinoin beat placebo on acne lesion counts

Source: Kakpovbia EE, et al. J Eur Acad Dermatol Venereol 2025;39(4):775-784
  • Gold standard

    A 2024 review of 25 studies calls topical tretinoin the gold standard for photoaging, with irritation as its main limit

    Source: Siddiqui Z, et al. Am J Clin Dermatol 2024;25(6):873-890 (systematic review)
  • 3 to 4 months

    The Renova label says some effect on fine wrinkles shows around 3 to 4 months, and up to 6 months may be needed

    Source: Renova (tretinoin) cream 0.02% prescribing information

Figures come from published trials and reviews and from the brand-name Renova 0.02% label. Our 0.05% tretinoin with niacinamide is compounded and was not studied in them. Individual results vary.

Start without the risk

  • $20 review refunded if not prescribed
  • Cancel anytime
  • Full refund before your blood draw

For your skin. And the rest of your day.

Thoughtful care for skin concerns, with room for the life you want to live.

A man in a peach t-shirt pouring tea at a bright home kitchen counter in soft morning light.

Keep care simple

A routine you can understand and come back to.

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Make room for daily protection

Small habits that belong in your everyday.

Man with a short beard sitting in warm sunlight

Feel present for your life

For plans, conversations, and moments beyond the mirror.

What changes the result

Three things that matter alongside treatment.

  1. 01

    Protect the skin barrier

    A gentle cleanser and a daily moisturizer keep the barrier intact, which is what tretinoin tests in the first weeks. A stronger barrier means fewer dropouts.

  2. 02

    Calm what is inflaming it from inside

    Stress, gut health and the immune system all feed into skin. A food pattern built on anti-inflammatory foods, steady sleep and a stress outlet give the cream a better starting point.

  3. 03

    Let sunlight stop undoing the work

    Sun exposure is the main driver of photoaging and makes retinoid-treated skin burn more easily. A daily broad-spectrum sunscreen and a hat protect the progress you are building.

Your skin-care journey.

Tell your clinician about your skin concerns, current products, medicines, and health history before discussing prescription options.

If treatment is prescribed, follow your clinician’s instructions and ask how it fits with the products you already use.

Keep track of how your skin feels. Contact your care team about irritation or other concerns rather than pushing through them.

Review your experience with your clinician. Changes to your routine should reflect your skin’s response and your treatment plan.

Stay in touch as your skin or health needs change. Your clinician can help you reassess what belongs in your routine.

DISCLAIMER

These stages describe a care process, not a promised schedule of skin improvement. Results and tolerability vary by condition and treatment. Follow your clinician’s instructions. Compounded medications are not FDA-approved.

Research:AAD: Retinoids and retinol

From goal to doorstep in four steps

Woman completing a private online health intake at home

Step 1

Tell us your goals

A few minutes

Step 1

Tell us your goals

A short, private intake about your health and what you want to improve.

A few minutes

A man with gray hair in a cream knit sweater relaxing on a sunny terrace beside olive trees, smiling during a phone call.

Step 2

A clinician reviews

Within 24 hours

Step 2

A clinician reviews

A licensed provider reviews your info and labs, if needed, and builds your plan.

Within 24 hours

Discreet treatment delivery

Step 3

Delivered to your door

2–5 business days

Step 3

Delivered to your door

Approved treatment ships free in plain, discreet packaging.

2–5 business days

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Step 4

Ongoing care

Ongoing

Step 4

Ongoing care

Message your PocketMD provider anytime; we adjust your plan as you progress.

Ongoing

Explore treatments

Your questions, answered.

A Latino man in his late 40s with greying temples reading a message from his care team
Which skin treatment is right for me?+

Your clinician reviews your concerns, skin-care routine, and health history before deciding whether a prescription fits. Availability alone does not mean a treatment is right for every person.

How do I fit a retinoid into my routine?+

Ask your clinician how to introduce it and which other products to use. Retinoids can irritate skin; sun protection is important. Contact your care team if your skin becomes painful or irritated.

Is tretinoin the same as retinol?+

No. Tretinoin is a prescription retinoid; retinol is sold over the counter. Your clinician decides whether a prescription fits your skin.

Will I automatically get a prescription?+

No. A licensed clinician reviews your information and prescribes only when appropriate. You may be advised to seek another form of care.

What does it cost to start?+

A $20 clinician review, refunded if you’re not prescribed. Each plan shows its lowest rate with the real bill, and you can cancel anytime.

How fast is it?+

A US-licensed clinician reviews within 24 hours, and approved orders ship free in 2 to 5 business days.

The clinicians behind your care

Your treatment is reviewed and prescribed by US-licensed clinicians in our network.

Meenal Kheterpal, MD, FAAD

Meenal Kheterpal, MD, FAAD

Dermatology

Board certified dermatologist and Associate Professor of Dermatology at Duke University School of Medicine. Specializes in skin cancer and dermato-oncology.

William Blackwell, MD

William Blackwell, MD

Weight and metabolic health

Board certified in emergency medicine and practicing telehealth since 2018. Focuses on weight management and metabolic health.

Explore other goals

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One tablet a day, dosed from your labs.

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A plan built around your health, your routines, and where you want to go.

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Closer. More you.

Make room for connection. Find private care that fits you.

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Your hair. Your way.

Get ahead of thinning. Find a hair-care routine that fits your life.

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Keep your thyroid levels steady.

Levothyroxine from a US pharmacy, dosed from your TSH and free T4.

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Low B12, fixed at the source.

A weekly methylcobalamin injection that skips your gut.

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Your skin deserves a thoughtful conversation.

Breakouts, texture, or a routine that feels complicated? Start with what you have been noticing.

Explore clinician-guided options and a plan that considers your skin and your health.

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Stay on top of your health.

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Prescription products require an online consultation with a licensed clinician who will determine if a prescription is appropriate. Individual results vary. Not for use in a medical emergency. © Vitals Vault

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From $1.28/day · $20 clinician review.

Billed $229 every 180 days. $20 review refunded if not prescribed. Cancel anytime.

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