
Tretinoin + Niacinamide Cream
From $1.28/day

Your skin. Your everyday.
Clearer, smoother skin with one simple nightly step, prescribed for you.

From $1.28/day
You’re far from the only one. A US-licensed clinician looks at what you’re noticing and whether treatment fits you.

35 trials
In 33,472 people, single topical agents including tretinoin beat placebo on acne lesion counts
Source: Kakpovbia EE, et al. J Eur Acad Dermatol Venereol 2025;39(4):775-784Gold standard
A 2024 review of 25 studies calls topical tretinoin the gold standard for photoaging, with irritation as its main limit
Source: Siddiqui Z, et al. Am J Clin Dermatol 2024;25(6):873-890 (systematic review)3 to 4 months
The Renova label says some effect on fine wrinkles shows around 3 to 4 months, and up to 6 months may be needed
Source: Renova (tretinoin) cream 0.02% prescribing informationFigures come from published trials and reviews and from the brand-name Renova 0.02% label. Our 0.05% tretinoin with niacinamide is compounded and was not studied in them. Individual results vary.
Thoughtful care for skin concerns, with room for the life you want to live.

A routine you can understand and come back to.

Small habits that belong in your everyday.

For plans, conversations, and moments beyond the mirror.
Three things that matter alongside treatment.
A gentle cleanser and a daily moisturizer keep the barrier intact, which is what tretinoin tests in the first weeks. A stronger barrier means fewer dropouts.
Stress, gut health and the immune system all feed into skin. A food pattern built on anti-inflammatory foods, steady sleep and a stress outlet give the cream a better starting point.
Sun exposure is the main driver of photoaging and makes retinoid-treated skin burn more easily. A daily broad-spectrum sunscreen and a hat protect the progress you are building.
Tell your clinician about your skin concerns, current products, medicines, and health history before discussing prescription options.

Step 1
A few minutes

Step 2
Within 24 hours

Step 3
2–5 business days

Step 4
Ongoing

Your clinician reviews your concerns, skin-care routine, and health history before deciding whether a prescription fits. Availability alone does not mean a treatment is right for every person.
Ask your clinician how to introduce it and which other products to use. Retinoids can irritate skin; sun protection is important. Contact your care team if your skin becomes painful or irritated.
No. Tretinoin is a prescription retinoid; retinol is sold over the counter. Your clinician decides whether a prescription fits your skin.
No. A licensed clinician reviews your information and prescribes only when appropriate. You may be advised to seek another form of care.
A $20 clinician review, refunded if you’re not prescribed. Each plan shows its lowest rate with the real bill, and you can cancel anytime.
A US-licensed clinician reviews within 24 hours, and approved orders ship free in 2 to 5 business days.
Your treatment is reviewed and prescribed by US-licensed clinicians in our network.

Dermatology
Board certified dermatologist and Associate Professor of Dermatology at Duke University School of Medicine. Specializes in skin cancer and dermato-oncology.

Weight and metabolic health
Board certified in emergency medicine and practicing telehealth since 2018. Focuses on weight management and metabolic health.

One tablet a day, dosed from your labs.
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