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Men/Explore care/Tadalafil Daily
Free lab panel at month 3Start by Jan 31
Tadalafil tablets package

4.5 on Google

Tadalafil Daily

Tablet · 5 mg

Ready when the moment is. One 5 mg tablet a day, with nothing to time or plan around.

$3.78/dayBilled $679 every 180 days

Start my $20 doctor visit

Medication is charged only if your clinician prescribes it.

Free lab panel with your treatment Start by Jan 31

Testosterone Check

Given at your 3-month mark as a progress check.

  • US clinicians
  • Licensed pharmacy
  • LegitScript
  • $20 review refunded
  • Free discreet shipping
  • One small tablet a day, nothing to time
  • Works with or without food
  • Reviewed by a US clinician, shipped privately
Choose your plan

Start with a $20 clinician review

The review fee is refunded if you’re not prescribed. Medication is billed separately only if prescribed.

Start my $20 doctor visit

Prescribed only if appropriate. Compounded medications are not FDA-approved. Review the full terms in checkout.

What the research shows

57%

of attempts kept an erection long enough for intercourse on 5 mg daily, vs 31% on placebo (24 weeks)

Source: Cialis prescribing information, section 14 (once-daily study H)
  • 31,195 men

    across 118 trials: tadalafil and vardenafil came out as the most effective oral ED tablets in a network meta-analysis

    Source: Yuan J, et al. Eur Urol 2013;63(5):902-12 (systematic review and network meta-analysis)
  • 67%

    the same measure in a second 12-week trial of 5 mg daily, vs 37% on placebo (163 men)

    Source: Cialis prescribing information, section 14 (once-daily study I)
  • 17.5 hours

    average half-life, so a daily tablet stays active between doses; levels settle within 5 days

    Source: Cialis prescribing information, section 12.3

Trial results are for brand tadalafil (Cialis) and for approved ED tablets as a group. Our tadalafil is a compounded 5 mg tablet from a licensed US pharmacy and was not studied in these trials. Individual results vary.

Tadalafil 5 mg daily: 57%, Placebo: 31%
57%Tadalafil 5 mg daily
31%Placebo

The Always-Ready Plan

Stay ready without planning around a tablet, with a clinician-reviewed daily prescription delivered privately.

Everything included

  • Licensed clinician review

    A US-licensed clinician checks your health history, blood pressure, urinary symptoms and medicines before prescribing.

  • Prescription tadalafil 5 mg tablets

    Compounded and dispensed by a licensed US pharmacy, one tablet a day, in a 90 or 180 day supply.

  • Free, plain-packaged shipping

    Ships 2 to 5 business days after approval.

  • Care-team messaging

    Tell us how it is going and your clinician can adjust your plan.

Bonuses

  • Free lab panel at month 3

    Testosterone Check, as a progress check.

  • “I do not want to plan sex around a pill.”

    No timing, no planning

    One tablet a day, with or without food, so the moment does not have a clock on it.

  • “I do not want to talk about this face to face.”

    No appointment, no waiting room

    Questions online, review within 24 hours, tablets at your door.

  • “Is it safe with my other medicines?”

    Medicine and blood pressure screening included

    Nitrates, alpha blockers and heart history are checked before anything ships.

Tadalafil tablets package

180-day supply

$3.78/day

Billed $679 every 180 days

  • Ro generic Cialis, 4 doses a month (source)$176/mo
  • Your plan, per month$113.17/mo
  • $20 review refunded if not prescribed
  • Cancel anytime

Free, discreet shipping

Start my $20 doctor visit

Start today: your clinician reviews within 24 hours, and tablets ship 2 to 5 business days after approval.

Labs we cover

Testosterone Check

  • Total testosterone
  • Free testosterone

Start or transfer your treatment between Nov 1 and Jan 31 and get this panel free at your 3-month mark. Labs are a bonus, not needed to start treatment.

From questions to your first daily tablet

Arousal releases nitric oxide, which relaxes the muscle in the penis and lets blood flow in. An enzyme called PDE5 breaks that signal down. Tadalafil blocks PDE5, and because it clears slowly, with a half-life of about 17.5 hours, a low daily dose keeps it active between doses. It supports the response when you are aroused and does not create desire.

Erections depend on healthy blood vessels, which is why ED often travels with high blood pressure, diabetes and high cholesterol. Your clinician looks at those first, then prescribes only if tadalafil is safe and right for you.

One small tablet a day, ready when you are. A low daily dose means you never have to time a pill. Your clinician can switch you to as-needed dosing instead.

  1. 1
    Step 1
    An East Asian man in his mid 40s looking over his lab results at home

    Answer a few questions

    Your health, your blood pressure, any urinary symptoms and every medicine you take. No video call, no waiting room.

    A few minutes

  2. 2
    Step 2
    Messaging the care team from home

    A clinician checks it is safe for you

    A US-licensed clinician screens for nitrates, heart health and blood pressure, and prescribes only if tadalafil fits.

    Within 24 hours

  3. 3
    Step 3
    A discreet package left at the front door

    Tablets ship in plain packaging

    From a licensed US pharmacy, with free shipping.

    2 to 5 business days

  4. 4
    Step 4
    A white man in his late 50s with close-cropped grey hair reading a message from his care team

    Take one every day

    Same time each day, with or without food. Support settles within about 5 days, and your care team adjusts with you.

    Ongoing support

Clear, rested skin in natural light

What to expect

  1. 01

    The first week

    Take one tablet at the same time every day. Levels settle within about 5 days, so judge it after a week, not after one night.

  2. 02

    Side effects

    Headache, indigestion, back or muscle aches and a stuffy nose are the most common. Tell your care team if they do not settle.

  3. 03

    Month one

    Message us about what you notice. Your clinician can adjust the plan, and urinary symptoms are worth mentioning too.

  4. 04

    When ED has been around a while

    Ask about a blood panel. Blood pressure, blood sugar and low testosterone can all stand behind it, and fixing them helps the tablet work.

What makes it work better

Three things you can do alongside your treatment.

  1. A South Asian man in his late 30s looking over his lab results at home
    01

    Treat the vessels, not just the symptom

    ED shares its risk factors with heart disease: blood pressure, blood sugar and cholesterol. Ask about a panel covering fasting glucose, A1C, lipids and free testosterone, and recheck it as you go.

  2. Two people stretching outdoors
    02

    Build muscle, break up sitting

    Muscle works as a metabolic organ that helps your body handle blood sugar. Strength training and a walk after meals support the same vessels the tablet relies on.

  3. Man looking out of his window in the morning
    03

    Give your stress a place to go

    Chronic stress keeps cortisol up and can shut down arousal. Daily movement, outdoor time and steady sleep lower that load, and a daily tablet means one less thing to perform around.

Daily tadalafil, sildenafil or PT-141

FeatureTadalafil dailySildenafilPT-141
When you take itOne tablet every day, whether or not sex is plannedAbout 1 hour before sex, as neededAt least 45 minutes before sex, as needed
How long it lastsStays active between daily doses (half-life 17.5 hours)Up to about 4 hours, strongest in the first 2Set by the dose; one in 24 hours at most
FoodNo effectA high-fat meal can delay it by about an hourCan slow how fast oral medicines absorb
Also on the brand labelUrinary symptoms of an enlarged prostate at 5 mg dailyErectile dysfunction onlyLow desire in premenopausal women only
Best forNot wanting to plan around a tabletPlanned momentsLow desire more than erection trouble
Regulatory statusCompounded, not FDA approvedCompounded, not FDA approvedCompounded, not FDA approved; off-label in men

Our tadalafil is a 5 mg daily tablet. Your clinician recommends the right option from your health history.

Before you start

  • Never take it with nitrates (often prescribed for chest pain) or with riociguat. Tell us if you use either.
  • Alpha blockers and some blood pressure medicines need care. Share every medicine, including supplements.
  • Pick a time of day you can keep, such as with breakfast. Mention urinary symptoms and heart disease.
  • Get urgent care for an erection lasting more than 4 hours, sudden vision or hearing loss, or chest pain.

How to take it

Take 1 tablet (5 mg) by mouth once a day, at about the same time each day, with or without food. Do not take more than one tablet in 24 hours.

Side effects and safety

Tell your care team straight away if an erection lasts longer than 4 hours, you lose vision suddenly, your hearing drops suddenly, or you get chest pain or severe dizziness or you faint after a dose.

Common side effects

  • headache
  • indigestion
  • back pain
  • muscle pain
  • a stuffy nose
  • flushing
  • pain in your arms or legs

Rare but serious

  • priapism, a painful erection that will not go down
  • sudden vision loss from reduced blood flow to the optic nerve
  • sudden hearing loss
  • a severe drop in blood pressure with nitrates or alpha blockers
  • heart problems brought on by sex

Do not take this if you take any nitrate, you take riociguat, or you have reacted badly to tadalafil before.

This is not a complete list of side effects. Message your care team about any symptom that worries you.

Your questions, answered.

A Latino man in his late 40s with greying temples reading a message from his care team
How long until daily tadalafil works?+

The brand label reports steady levels within 5 days of daily dosing. Take it at the same time each day and give it about a week before judging.

Can I take it only when I need it?+

Ours is a 5 mg tablet taken once a day, and it stays active between doses. If you only want something for planned moments, sildenafil is the as-needed option we offer.

Can I drink alcohol on it?+

Keep it moderate. The brand label warns that five or more units of alcohol, especially with blood pressure medicines or alpha blockers, can drop your blood pressure.

Will it help urinary symptoms?+

The brand 5 mg daily dose is also approved for urinary symptoms of an enlarged prostate. Tell your clinician if you have them. Ours is compounded and was not part of those trials.

What side effects are common?+

Headache, indigestion, back or muscle aches, flushing and a stuffy nose. Back ache is more typical of tadalafil than sildenafil.

Is it the same as Cialis?+

It has the same active ingredient, but ours is compounded by a licensed US pharmacy and is not FDA approved. The numbers above come from trials of the brand, which did not test our version.

What if I stop taking it?+

Support fades as the medicine clears over a few days, because the half-life is 17.5 hours. Nothing about it is permanent, and you can restart with your clinician.

The Always-Ready Plan

  • Reviewed by a US-licensed clinician, and prescribed only if it suits you
  • Filled by a licensed US pharmacy
  • Free, discreet shipping to your door
  • LegitScript certified, and rated 4.5 on Google

180-day supply · $3.78/day · Billed $679 every 180 days

Start my $20 doctor visit
  • $20 review refunded if not prescribed
  • Cancel anytime
  • Free, discreet shipping
A Middle Eastern man in his mid 30s with dark curly hair on a video visit with his clinician at home

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$3.78/day

Billed $679 every 180 days

Start $20 visit