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Men/Explore care/Enclomiphene
Free lab panel at month 3Start by Jan 31
Enclomiphene tablets bottle

4.5 on Google

Enclomiphene

Tablet · 12.5 mg / 25 mg

Raise your own testosterone without shutting down sperm production. One tablet a day, dosed with you.

$2.61/dayBilled $469 every 180 days

Start my $20 doctor visit

Medication is charged only if your clinician prescribes it.

Free lab panel with your treatment Start by Jan 31

Green-Light Hormone Check worth $52.99

Given at your 3-month mark as a progress check.

  • US clinicians
  • Licensed pharmacy
  • LegitScript
  • $20 review refunded
  • Labs clinician-reviewed
  • Signals your body to make its own testosterone
  • Kept sperm counts normal in phase III trials
  • One small tablet a day, no injections

Recommended lab testing

Not required to start. Your clinician may suggest it to tailor and monitor your care.

RX-Enclomiphene Qualifying Panel · $94.99

See the 10 tests included

Testosterone, Total (LC/MS), Testosterone, Free (Equilibrium Dialysis), Luteinizing Hormone (LH), Follicle Stimulating Hormone (FSH), Sex Hormone Binding Globulin (SHBG), Prolactin, Estradiol, Ultrasensitive (LC/MS), Total PSA, Free PSA, PSA, % Free

Optional.

For this recommendation, results within 90 days can be reviewed.

RX-Enclomiphene Panel · $52.99

See the 5 tests included

Testosterone, Total (LC/MS), Testosterone, Free (Equilibrium Dialysis), Luteinizing Hormone (LH), Follicle Stimulating Hormone (FSH), Sex Hormone Binding Globulin (SHBG)

Optional.

Green-Light Hormone Check · $52.99

See the 2 tests included

FSH and LH, Testosterone, Free (Dialysis), Total and Sex Hormone Binding Globulin

Optional.

For this recommendation, results within 30 days can be reviewed.

Already have results?

Upload your results after you start, and your care team will review them.

Panel prices and any applicable lab visit fees are confirmed in checkout.

Choose your plan

Start with a $20 clinician review

The review fee is refunded if you’re not prescribed. Medication is billed separately only if prescribed.

Start my $20 doctor visit

Prescribed only if appropriate. Compounded medications are not FDA-approved. Review the full terms in checkout.

What the research shows

  • +216 ng/dL

    average testosterone rise on enclomiphene, pooled across clinical studies in a 2023 meta-analysis

    Source: Tienforti D, et al. Andrology 2023;11(6):1067-76 (meta-analysis)
  • Same as T gel

    Randomized trials found the same testosterone rise as testosterone gel, with LH and FSH up instead of shut down

    Source: Hohl A, et al. Arch Endocrinol Metab 2025;69(5) (meta-analysis of randomized trials)
  • Normal sperm

    Two double-blind phase III trials: sperm counts stayed in the normal range on enclomiphene and fell on testosterone gel

    Source: Kim ED, McCullough A, Kaminetsky J. BJU Int 2016;117(4):677-85
  • 2 weeks

    Testosterone started rising within 2 weeks of the first daily dose in a randomized trial

    Source: Wiehle R, et al. BJU Int 2013;112(8):1188-200 (randomized phase II)

Results from published trials and meta-analyses of enclomiphene citrate. The 2025 meta-analysis pools enclomiphene with clomiphene, its parent drug. Our enclomiphene is compounded by a licensed US pharmacy and was not studied in these trials. Individual results vary.

From below range to mid-range in 6 weeks

Morning total testosterone: Day 1 253 ng/dL, Week 6 604 ng/dL

HEALTHY ADULT RANGEBELOW RANGEDay 1Week 6253604
Morning total testosterone, ng/dL

Source: Wiehle R, et al. BJU Int 2013;112(8):1188-200, Table 1 (enclomiphene 25 mg) · Group average in a randomized trial, not a prediction for you.

The Testosterone Restore Plan

Feel like yourself again, with more drive and steadier energy, while your body keeps making its own testosterone and sperm.

Everything included

  • Licensed clinician review

    A US-licensed clinician reads your health history, symptoms, goals and any hormone labs you share, and prescribes only if enclomiphene fits.

  • Your prescription, filled

    Enclomiphene tablets compounded by a licensed US pharmacy, in a 90 or 180-day supply.

  • Free, discreet shipping

    Plain packaging to your door, 2 to 5 business days after approval.

  • Your care team on message

    Ask about side effects or your dose at any point, and your clinician can change it.

  • Day-90 recheck and dose fine-tune

    Repeat labs are optional. If you add them, your clinician reviews them and adjusts your dose with you. Any repeat test beyond your free lab panel is priced separately, with no lab visit fee.

  • Your numbers in your Vault

    Every result is stored in your Vault, so you can see where you started and where you are now.

Bonuses

  • Free lab panel at month 3

    Green-Light Hormone Check, as a progress check.

  • “I don't want another blood draw.”

    Use the labs you already have

    Upload recent results after you start, and your care team checks whether they cover the four markers.

  • “The labs will cost more than the medicine.”

    No lab visit fee for treatment members

    If you do need a draw, book one Quest visit near you without the usual visit fee.

  • “How will I know it's working?”

    Before-and-after numbers

    Your starting labs and your day-90 recheck sit side by side in your Vault.

Enclomiphene tablets bottle

180-day supply

$2.61/day

Billed $469 every 180 days

  • $20 review refunded if not prescribed
  • Cancel anytime
  • Full refund before your blood draw

Free, discreet shipping

Start my $20 doctor visit

Start today: your clinician reviews within 24 hours, and tablets ship 2 to 5 business days after approval.

Labs we cover

Green-Light Hormone Check

  • FSH
  • LH
  • Free testosterone
  • Total testosterone
  • SHBG

Start or transfer your treatment between Nov 1 and Jan 31 and get this panel free at your 3-month mark. Labs are a bonus, not needed to start treatment.

From your review to your first tablet

Enclomiphene is a daily tablet that lifts estrogen's brake on your brain, so your pituitary sends out more LH and FSH. Those two signals tell your testes to make more testosterone and keep making sperm. It restores your own production instead of replacing it, which is why men who want to protect fertility often choose it. Sleep, waist size and alcohol all push your own signal up or down, so they are worth working on alongside the tablet.

One tablet a day. No needles. Taken by mouth each morning. Repeat labs at about 90 days show how your levels moved, and your clinician sets your dose from those numbers.

  1. 1
    Step 1
    A white man in his late 50s with close-cropped grey hair looking over his lab results at home

    Optional: share your 4 lab numbers

    LH, SHBG, total and free testosterone help set your dose, but you can start without them. Upload recent results, or add a quick draw at a lab near you.

  2. 2
    Step 2
    Man completing an online consultation with a clinician to plan his care

    A licensed clinician reviews your levels

    They look at your labs, symptoms and goals, and prescribe only if enclomiphene fits. Reviewed within 24 hours.

  3. 3
    Step 3
    Messaging the care team from home

    Tablets ship from a US pharmacy

    If prescribed, your compounded enclomiphene ships free in plain packaging in 2 to 5 business days.

  4. 4
    Step 4
    A white man in his early 50s with a salt-and-pepper beard on a video visit with his clinician at home

    Recheck at 90 days and fine-tune

    Repeat labs show how far your levels moved, and your clinician adjusts your dose with you.

A couple out cycling by the sea

What to expect

  1. 01

    Before you start

    Your clinician checks LH, SHBG, total and free testosterone from a morning, fasted draw to confirm your body can respond.

  2. 02

    First weeks

    LH and FSH rise, and your testosterone starts to climb with them.

  3. 03

    Months 1 to 3

    Energy, drive and mood often improve as your levels settle. Results vary.

  4. 04

    Day 90

    Repeat labs show where you landed against the optimal ranges our clinicians use, such as total testosterone at the upper end of normal and free testosterone around 150 to 224 pg/mL, and your clinician fine-tunes your dose.

What makes it work better

Three things you can do alongside your treatment.

  1. Two people stretching outdoors
    01

    Trim the waist before you chase the number

    Extra belly fat turns testosterone into estrogen, and high insulin lowers SHBG, which pulls your levels down. In a lifestyle trial of men with a mean BMI of 32, losing about 8 kg raised testosterone without medicine. Walking daily and lifting weights help the tablet's signal land on a healthier base.

  2. Clear, rested skin in natural light
    02

    Guard your sleep, because testosterone peaks in the morning

    Poor sleep is linked to lower testosterone, and levels peak in the morning. Aim for 7 to 9 hours of unbroken sleep and book your draws between 7 and 11 am, fasted, so your day-90 numbers show what the tablet is really doing.

  3. A white man in his late 50s with close-cropped grey hair preparing a fresh, balanced meal
    03

    Eat for hormones and top up what is low

    A Mediterranean-style diet raised testosterone within 2 to 4 months in men with obesity-related low levels. Zinc, magnesium and vitamin D gaps are linked to lower testosterone, and alcohol pushes it down. Keep alcohol low, and ask your clinician whether a micronutrient check belongs in your Vault.

Enclomiphene, clomiphene or TRT

FeatureEnclomipheneClomiphene (Clomid)TRT injections
How it worksSignals your body to make more of its own testosteroneSame signal, mixed with zuclomiphene, a second form that clears slowly and builds upReplaces testosterone from outside, which switches your own production down
Sperm productionStayed in the normal range in phase III trialsUsually kept on; widely used off-label for male fertilityUsually suppressed; testosterone gel cut sperm counts in the same trials
FormatOne tablet a dayOne 25 mg capsule each morning, as prescribedAn injection once or twice a week
LabsFour markers to start, recheck at 90 daysSimilar hormone labs, plus estradiol at the recheckHormone labs plus hematocrit and PSA checks
Regulatory statusCompounded, not FDA approved; prescribed only if appropriateFDA approved for ovulation in women; prescribed off-label for menFDA approved for diagnosed low testosterone
Best forMen whose body still answers its own signals, including men protecting fertilityMen who want the older, longer-studied optionMen whose testes no longer respond, or who are not planning children

We offer enclomiphene and clomiphene. Your clinician recommends one from your labs.

Before you start

  • Optional: have your 4 numbers ready, or add a draw: LH, SHBG, total and free testosterone. You can start without them.
  • If you do test, book your blood draw in the morning, fasted, and use the same lab for your day-90 recheck so the numbers compare.
  • Tell your clinician if you are trying to conceive, or have had blood clots, liver disease or vision problems.
  • Already on testosterone? Do not stop on your own. Your clinician will plan the switch with you.
  • Enclomiphene is compounded by a licensed US pharmacy and is not FDA approved. It is prescribed only if it is right for you.

How to take it

One tablet by mouth each day, usually 12.5 mg or 25 mg. Your clinician picks your starting strength and adjusts it after your 90-day labs. Take it at the same time each day, with or without food.

Side effects and safety

Enclomiphene is not FDA approved for any use, so there is no FDA reviewed safety label for it. The side effects below were reported in the manufacturer's Phase 3 trials, not drawn from a label.

Tell your care team straight away if you get chest pain or shortness of breath, pain or swelling in a leg, sudden weakness or trouble speaking, blurred vision or flashes, or severe abdominal pain.

Common side effects

  • upper respiratory infection
  • headache
  • muscle spasms
  • hot flushes
  • sinus infection
  • dizziness
  • needing to pass urine more often

Rare but serious

  • blood clots in a leg or lung, reported in the trials
  • transient ischemic attack
  • an irregular heartbeat
  • gallstones and biliary pain

Who should not take it: there is no FDA-reviewed list of contraindications for enclomiphene. Your clinician decides whether it is appropriate from your history and your labs.

This is not a complete list of side effects. Message your care team about any symptom that worries you. What we dispense is a compounded preparation made by a licensed US pharmacy. Compounded medications are not approved by the FDA for safety, efficacy or quality.

Your questions, answered.

A Black man in his early 40s with a short beard reading a message from his care team
How is enclomiphene different from testosterone therapy?+

Testosterone therapy adds the hormone from outside, so your brain stops sending the signals that make your own testosterone and sperm. Enclomiphene blocks estrogen's brake on those signals, so your body makes more testosterone itself. In phase III trials it raised testosterone while keeping sperm concentration in the normal range; a testosterone gel did not.

Will it affect my fertility?+

It is chosen because it keeps sperm production on. In trials, sperm counts stayed normal or rose on enclomiphene. Those trials measured sperm counts, not pregnancies, so tell your clinician if you are trying to conceive and they can monitor you.

Do I need labs, and can I use results I already have?+

No. Labs are optional and never needed to start. If you have them, four markers help your clinician: LH, SHBG, total testosterone and free testosterone. Upload recent results after you start and your care team will review them, or add a quick draw at a lab near you. At your day-90 recheck your clinician reads them against the optimal ranges our clinicians use, and may also look at estradiol, because more testosterone can mean more estradiol.

Is enclomiphene the same as Clomid?+

No. Clomid (clomiphene) is a mix of two forms. Enclomiphene is the form that raises testosterone; the other, zuclomiphene, clears slowly and builds up over time. In a 2024 study of 66 men who used both, side effects were reported less often on enclomiphene. We offer both, and your clinician recommends one from your labs.

How long until I notice a change?+

Testosterone starts rising within about 2 weeks in trials, with LH and FSH leading the way. Most men notice energy, drive and mood over one to three months. We recheck labs at 90 days and adjust your dose.

What happens if I stop taking it?+

Your levels drift back toward where they started. In one trial, testosterone returned to its starting point within a month of stopping. Talk to your clinician before you stop, so they can plan what comes next.

Will it cause hair loss or acne?+

Higher testosterone also means more DHT, which can speed up hair loss in men who are prone to it, and some men notice oilier skin. If that matters to you, say so in your assessment; your clinician can suggest a hair treatment alongside.

Is it safe, and is it FDA approved?+

Enclomiphene is not FDA approved for any use. What we dispense is compounded by a licensed US pharmacy, and compounded medicines are not FDA reviewed for safety, efficacy or quality. In trials the common side effects were upper respiratory infection, headache, muscle spasms, hot flushes, dizziness and passing urine more often. Rare serious events included blood clots. Report vision changes or leg pain or swelling right away.

The Testosterone Restore Plan

  • Reviewed by a US-licensed clinician, and prescribed only if it suits you
  • Filled by a licensed US pharmacy
  • Free, discreet shipping to your door
  • LegitScript certified, and rated 4.5 on Google

180-day supply · $2.61/day · Billed $469 every 180 days

Start my $20 doctor visit
  • $20 review refunded if not prescribed
  • Cancel anytime
  • Full refund before your blood draw
  • Free, discreet shipping
A South Asian man in his late 30s on a video visit with his clinician at home

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$2.61/day

Billed $469 every 180 days

Start $20 visit