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Men/Explore care/Clomiphene
Free lab panel at month 3Start by Jan 31
Clomiphene capsules package

4.5 on Google

Clomiphene

Capsule · 25 mg

Raise your own testosterone with a daily capsule, dosed from your labs and backed by decades of use in men.

$2.99/dayBilled $269 every 90 days

Start my $20 doctor visit

Medication is charged only if your clinician prescribes it.

Free lab panel with your treatment Start by Jan 31

Green-Light Hormone Check worth $52.99

Given at your 3-month mark as a progress check.

  • US clinicians
  • Licensed pharmacy
  • LegitScript
  • $20 review refunded
  • Labs clinician-reviewed
  • Signals your body to make its own testosterone
  • Decades of use in men, followed for up to 7 years
  • One capsule each morning, not a controlled substance

Recommended lab testing

Not required to start. Your clinician may suggest it to tailor and monitor your care.

Green-Light Hormone Check · $52.99

See the 2 tests included

FSH and LH, Testosterone, Free (Dialysis), Total and Sex Hormone Binding Globulin

Recommended for your care.

For this recommendation, results within 30 days can be reviewed.

Already have results?

Upload your results after you start, and your care team will review them.

Panel prices and any applicable lab visit fees are confirmed in checkout.

Choose your plan

Start with a $20 clinician review

The review fee is refunded if you’re not prescribed. Medication is billed separately only if prescribed.

Start my $20 doctor visit

Prescribed only if appropriate. Compounded medications are not FDA-approved. Review the full terms in checkout.

What the research shows

88%

of 120 men on clomiphene for over 3 years reached normal testosterone; 77% reported better symptoms (retrospective)

Source: Krzastek SC, et al. J Urol 2019;202(5):1029-35 (400 men, two centers)
  • +274 ng/dL

    average testosterone rise vs placebo on clomiphene or enclomiphene, pooled across randomized trials

    Source: Hohl A, et al. Arch Endocrinol Metab 2025;69(5):e250093 (meta-analysis of randomized trials)
  • +333 ng/dL

    average testosterone rise on clomiphene in obese men with low testosterone, pooled across studies (11.56 nmol/L)

    Source: Tienforti D, et al. Andrology 2023;11(6):1067-76 (meta-analysis)
  • +8.4 million/mL

    higher sperm concentration during clomiphene in infertile men, pooled across 15 studies and 566 men

    Source: Huijben M, et al. Andrology 2023;11(6):987-96 (meta-analysis)

Results from published meta-analyses and a retrospective review of clomiphene in men. The 2025 meta-analysis pools clomiphene with enclomiphene, and the 2023 testosterone figure is from obese men with functional low testosterone. Use in men is off-label, and ours is compounded by a licensed US pharmacy and was not studied in these reports. Individual results vary.

Normal testosterone: 88%, Better symptoms: 77%
88%Normal testosterone
77%Better symptoms

The Longest-Track-Record Testosterone Plan

Feel like yourself again, with more drive and steadier energy, from the option with the longest record of use in men.

Everything included

  • Licensed clinician review

    A US-licensed clinician reads your baseline hormone labs, symptoms and history, and prescribes only if clomiphene fits.

  • Your prescription, filled

    Clomiphene 25 mg capsules compounded by a licensed US pharmacy, as a 30-day or 90-day plan filled in 30-day shipments.

  • Free, discreet shipping

    Plain packaging to your door, 2 to 5 business days after approval.

  • Your care team on message

    Ask about vision, mood or your dose at any point, and your clinician can change your plan.

  • Recheck at 8 to 12 weeks

    Your clinician reviews your repeat labs, including estradiol, and adjusts your plan with you.

  • Your numbers in your Vault

    Every result is stored in your Vault, so you can see where you started and where you are now.

Bonuses

  • Free lab panel at month 3

    Green-Light Hormone Check, as a progress check.

  • “I do not want to commit to months before I know it works for me.”

    Start with 30 days

    A 30-day plan lets you try clomiphene without committing to a longer supply.

  • “I do not want another blood draw.”

    Use the labs you already have

    Upload recent results, and your care team checks whether they cover what your clinician needs.

  • “The labs will cost more than the medicine.”

    No lab visit fee for treatment members

    If you do need a draw, book a Quest visit near you without the usual visit fee.

Clomiphene capsules package

90-day supply

$2.99/day

Billed $269 every 90 days

  • Month-to-month enclomiphene, the closest alternative, at a leading online men's clinic (source)$199.99/mo
  • Your plan, per month$89.67/mo
  • $20 review refunded if not prescribed
  • Cancel anytime
  • Full refund before your blood draw

Free, discreet shipping

Start my $20 doctor visit

Start today: your clinician reviews within 24 hours, and capsules ship 2 to 5 business days after approval.

Labs we cover

Green-Light Hormone Check

  • FSH
  • LH
  • Free testosterone
  • Total testosterone
  • SHBG

Start or transfer your treatment between Nov 1 and Jan 31 and get this panel free at your 3-month mark. Labs are a bonus, not needed to start treatment.

From baseline labs to your first capsule

Estrogen puts a brake on the brain's signal to your testes. Clomiphene lifts that brake, so your pituitary sends out more LH and FSH, and your testes make more testosterone and keep making sperm. Clomiphene is a mix of two forms, enclomiphene and zuclomiphene, and the second clears slowly. Your dose is guided by labs, not symptoms alone, and body weight, sleep and alcohol shape how well it works.

One capsule, daily or every other day. Your clinician sets the schedule and checks your labs again at 8 to 12 weeks before adjusting anything.

  1. 1
    Step 1
    Man completing an online consultation with a clinician to plan his care

    Share your baseline hormone labs

    Upload recent results, or add a quick morning draw at a lab near you, so your clinician can see where you start.

  2. 2
    Step 2
    Messaging the care team from home

    A licensed clinician reviews your levels

    They look at your labs, symptoms, vision and liver history, and prescribe only if clomiphene fits. Reviewed within 24 hours.

  3. 3
    Step 3
    A Latino man in his late 40s with greying temples opening a plain delivery box at home while talking with his clinician

    Capsules ship from a US pharmacy

    If prescribed, your compounded capsules ship free in discreet packaging in 2 to 5 business days. A 90-day plan arrives as three monthly shipments.

  4. 4
    Step 4
    A Middle Eastern man in his mid 30s with dark curly hair on a video visit with his clinician at home

    Recheck at 8 to 12 weeks and fine-tune

    Repeat labs show how far your testosterone and estradiol moved, and your clinician adjusts your plan with you.

A couple out cycling by the sea

What to expect

  1. 01

    Before you start

    Your clinician reviews total and free testosterone and related hormones from a morning, fasted draw to see where you begin.

  2. 02

    First weeks

    LH and FSH rise first, and your testosterone climbs with them.

  3. 03

    Weeks 8 to 12

    Repeat labs show where you landed, including estradiol, against the optimal ranges our clinicians use, such as testosterone at the upper end of normal and estradiol around 24 to 39 pg/mL.

  4. 04

    Months 1 to 3

    Energy, drive and mood often improve as your levels settle. Results vary.

What makes it work better

Three things you can do alongside your treatment.

  1. A Black man in his early 40s with a short beard preparing a fresh, balanced meal
    01

    Trim the waist and lift weights

    Extra belly fat turns testosterone into estrogen and lowers SHBG, which drags your levels down. In a lifestyle trial of men with a mean BMI of 32, losing about 8 kg raised testosterone without medicine. Resistance training and daily walking help clomiphene's signal land on a healthier base.

  2. Clear, rested skin in natural light
    02

    Protect 7 to 9 hours of sleep

    Poor sleep is linked to lower testosterone, and testosterone peaks in the morning. Steady sleep keeps your morning level honest, so your repeat labs show what the capsule is really doing.

  3. A white man in his early 50s with a salt-and-pepper beard preparing a fresh, balanced meal
    03

    Eat for hormones, and cut the drink

    A Mediterranean-style diet raised testosterone within 2 to 4 months in men with obesity-related low levels, and zinc, magnesium and vitamin D gaps are linked to lower testosterone. Keep alcohol low and ask whether a micronutrient check is worth adding to your labs.

Clomiphene, enclomiphene or TRT

FeatureClomipheneEnclomipheneTRT injections
How it worksBlocks estrogen's brake on the brain so your body signals for more testosteroneThe same signal, from the single form of the drug that raises testosteroneReplaces testosterone from outside, which switches your own production down
What is in itA mix of two forms; zuclomiphene clears slowly and builds up over timeEnclomiphene onlyTestosterone
Track record in menDecades of off-label use; hundreds of men followed for up to 7 yearsNewer; trials up to 16 weeks and the 2025 meta-analysisLongest and best studied
FormatOne 25 mg capsule each morningOne tablet a dayAn injection once or twice a week
Regulatory statusApproved by the FDA for ovulation in women; off-label in men; compoundedCompounded, not FDA approved for any useFDA approved for diagnosed low testosterone
Best forMen who want the longer-studied option and a lower-commitment 30-day startMen who want the single-form optionMen whose testes no longer respond, or who are not planning children

We offer clomiphene and enclomiphene. Your clinician recommends one from your labs and plans.

Before you start

  • Stop and message your clinician right away if you notice any change in your vision.
  • Book your baseline blood draw in the morning, fasted, and use the same lab for your repeat so the numbers compare.
  • Tell your clinician if you are trying to conceive, or have liver disease or a past reaction to clomiphene.
  • Already on testosterone? Do not stop on your own. Your clinician will plan the switch with you.
  • Clomiphene is used off-label in men and ours is compounded by a licensed US pharmacy, so it is not FDA approved for this use. It is prescribed only if it is right for you.

How to take it

One 25 mg capsule by mouth each morning. Your clinician reviews your labs at 8 to 12 weeks and may adjust your schedule.

Side effects and safety

Clomiphene is FDA approved to treat ovulation problems in women trying to conceive. Using it in men is off-label, which means the FDA has not reviewed it for this use. The side effects below were reported in women taking it for the approved use, so how often they happen in men is not established.

Tell your care team straight away if you get blurred vision, spots or flashes, severe abdominal or pelvic pain, sudden abdominal swelling, shortness of breath, or rapid weight gain.

Common side effects

  • hot flushes
  • abdominal or pelvic discomfort
  • nausea or vomiting
  • breast discomfort
  • visual symptoms
  • headache

Rare but serious

  • visual symptoms that can last or become permanent, more likely at higher doses or longer use
  • abdominal swelling and shortness of breath
  • liver problems

Do not take this if you have liver disease, or you have reacted badly to clomiphene before.

This is not a complete list of side effects. Message your care team about any symptom that worries you. What we dispense is a compounded preparation made by a licensed US pharmacy. Compounded medications are not approved by the FDA for safety, efficacy or quality.

Your questions, answered.

An East Asian man in his mid 40s reading a message from his care team
How is clomiphene different from testosterone therapy?+

Testosterone therapy supplies the hormone from outside, which switches down your own signalling. Clomiphene prompts your body to make more testosterone itself. In the 2025 meta-analysis of randomized trials, it raised testosterone about as much as testosterone gel, with LH and FSH up instead of shut down.

Is clomiphene approved for men?+

Clomiphene is approved by the FDA to treat ovulation problems in women. Using it in men is off-label, meaning the FDA has not reviewed it for that use, although it has been used this way for years and studied in hundreds of men. What we dispense is compounded and not FDA evaluated.

Clomiphene or enclomiphene, which one?+

Clomiphene is a mixture of two forms; enclomiphene is the single form that does the useful work, and zuclomiphene clears slowly and builds up. Clomiphene has far more long-term data in men and a lower-commitment 30-day start. In a 2024 study of 66 men who used both, side effects were reported less often on enclomiphene. Your clinician helps you choose from your labs and plans.

Will it affect my fertility?+

It is often chosen because it keeps your own production on. In a meta-analysis of infertile men, sperm concentration and motility were higher during clomiphene. Randomized trials have not shown more pregnancies than placebo, so tell your clinician if you are trying to conceive and they can monitor you.

What about the vision side effect?+

A small number of people report blurring, floaters or light sensitivity. If you notice any change, stop and message your clinician right away rather than waiting.

Will my estrogen go up?+

It can, because more testosterone means more is converted to estradiol, and estradiol rose significantly in the 400-man review. We check it on follow-up labs and your clinician manages it if needed.

How long until my levels change?+

Levels usually move within weeks, with LH and FSH leading. We check labs at 8 to 12 weeks to see where you landed and adjust your plan. Energy, drive and mood often follow over one to three months.

What happens if I stop?+

Your levels drift back toward where they started. Talk to your clinician before you stop, so they can plan what comes next.

The Longest-Track-Record Testosterone Plan

  • Reviewed by a US-licensed clinician, and prescribed only if it suits you
  • Filled by a licensed US pharmacy
  • Free, discreet shipping to your door
  • LegitScript certified, and rated 4.5 on Google

90-day supply · $2.99/day · Billed $269 every 90 days

Start my $20 doctor visit
  • $20 review refunded if not prescribed
  • Cancel anytime
  • Full refund before your blood draw
  • Free, discreet shipping
A Latino man in his late 40s with greying temples on a video visit with his clinician at home

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$2.99/day

Billed $269 every 90 days

Start $20 visit