Compounded tirzepatide with glycine and B12: a weekly injection that works on two appetite hormones and supports steady weight loss alongside food and movement changes. Prescribed after a licensed clinician reviews your history.
One weekly injection that targets two appetite hormones and trims your waist, with B12 in every dose.
$42.25/weekBilled $169 every 4 weeks
Medication is charged only if your clinician prescribes it.
Every 28 days
$42.25/week
Free shipping with prescribed treatment.
Today you only pay a $20 clinician review, refunded if you’re not prescribed. Your plan starts only if prescribed.
Prescribed only if appropriate · Compounded medications are not FDA-approved.
15% to 21%
average body weight lost at 72 weeks on branded tirzepatide 5, 10 and 15 mg, vs 3.1% on placebo
Source: Jastreboff AM, et al. SURMOUNT-1, N Engl J Med 2022;387(3):205-1620.2% vs 13.7%
average weight lost at 72 weeks, branded tirzepatide vs branded semaglutide, head to head
Source: Aronne LJ, et al. SURMOUNT-5, N Engl J Med 2025;393(1):26-36 (open-label)85% to 91%
lost at least 5% of their body weight at 72 weeks across the three doses, vs 35% on placebo
Source: Jastreboff AM, et al. SURMOUNT-1, N Engl J Med 2022;387(3):205-1657%
lost 20% or more of their body weight on the 15 mg dose at 72 weeks, vs 3% on placebo
Source: Jastreboff AM, et al. SURMOUNT-1, N Engl J Med 2022;387(3):205-16Results from trials of FDA-approved tirzepatide in adults without diabetes, with diet and activity support. Our tirzepatide is compounded by a licensed US pharmacy, includes glycine and B12, is not FDA approved and was not studied in these trials. Individual results vary.
Average body weight lost: Day 1 0%, Week 36 20.9%, Week 88 25.3%
Source: Aronne LJ, et al. SURMOUNT-4, JAMA 2024;331(1):38-48 (branded tirzepatide, continued group) · Group average in a trial where everyone took the top tolerated dose for 36 weeks first, then half kept going. Not a prediction for you.
Two appetite hormones targeted by one weekly injection, with B12 and glycine already in the vial and a clinician who steps your dose up for you.
Licensed clinician review
A US-licensed clinician reads your history, goals and medicines, and prescribes only if tirzepatide fits.
Your prescription, filled
Compounded tirzepatide with glycine and B12, made by a licensed US pharmacy and sent in 28-day supplies.
Free, discreet shipping
Plain packaging to your door, 2 to 5 business days after approval.
Dose steps built in
Your clinician raises your dose in small steps, at least four weeks apart, and each supply matches your current dose.
Your care team on message
Ask about nausea, appetite or your next step at any point, and your clinician can change the plan.
Semaglutide on the table too
We offer both medicines, so your clinician can switch the recommendation if tirzepatide is not the right fit.
Free lab panel at month 3
Metabolic Check, as a progress check.
“Faster weight loss worries me: I'm afraid of feeling drained and losing muscle.”
B12 and glycine in every dose
Added by the prescriber to help reduce fatigue and muscle loss during weight loss, with nothing extra to buy or remember.
“I'd like numbers, not just the scale.”
No lab visit fee for treatment members
If you want bloodwork to track your progress, book a Quest visit near you without the usual visit fee.
“I don't have time for clinic visits.”
Care from your couch
Assessment, clinician review and dose changes happen online, with no waiting room.
Metabolic Check
Stubborn weight is often appetite signals and insulin that stopped working in your favor. Tirzepatide copies two gut hormones, GIP and GLP-1. Together they slow how fast your stomach empties, quiet hunger and help your body respond to insulin. Our version adds glycine, to help reduce muscle loss during weight loss, and vitamin B12, to help reduce fatigue and maintain vitamin levels. Those additions were not tested in the trials.
Weight history, goals, conditions and medicines, in a short online assessment.
They check that tirzepatide fits and set your starting dose. Reviewed within 24 hours.
If prescribed, it arrives free in plain packaging in 2 to 5 business days.
The first four weeks use the lowest dose, so your body can adjust before the dose steps up.
Your clinician adjusts your dose with you, and you message your care team whenever you need.
You start at the lowest dose. Hunger and portions often shrink first; the scale can lag.
Your clinician raises the dose in small steps, at least four weeks apart. Nausea is most likely right after a step, and smaller, slower meals help.
Weight keeps coming down. In the main trial the dose stepped up over 20 weeks and the average kept falling through week 72.
Weight tends to return if treatment stops, so you and your clinician plan the long game together.
Three things you can do alongside your treatment.
Bigger weight loss means more lean mass at stake. Protein at every meal and strength training two or more days a week help protect it, and muscle also helps clear blood sugar.
Long stretches of sitting go with a larger waist and more abdominal fat. Stand or walk every 30 minutes or so, and aim for 150 to 300 minutes of moderate movement a week.
Stubborn weight often traces back to insulin resistance. Our clinicians look at HbA1c (optimal 4.6 to 5.3%), triglycerides (optimal 50 to 80 mg/dL) and vitamin B12 (optimal 545 to 1100 pg/mL).
| Feature | Our tirzepatide + B12 | FDA-approved tirzepatide | Our semaglutide + B12 |
|---|---|---|---|
| How it works | Copies two gut hormones, GIP and GLP-1 | The two-hormone signal, studied in the trials shown | Copies one gut hormone, GLP-1 |
| What is in the vial | Tirzepatide with glycine and B12 | Tirzepatide | Semaglutide with glycine and B12 |
| Starting dose | 2.5 mg once a week for four weeks | 2.5 mg once a week for four weeks, per the label | 0.25 mg once a week for four weeks |
| Regulatory status | Compounded, not FDA approved | FDA approved for chronic weight management | Compounded, not FDA approved |
| Evidence | Trial data is for the branded drug, not this preparation | Studied directly in the trials shown | Trial data is for the branded drug, not this preparation |
| Getting it | Online review, ships from a US pharmacy | Prescription filled at a retail pharmacy | Online review, ships from a US pharmacy |
We offer tirzepatide and semaglutide. Your clinician recommends one from your history.
Inject under the skin once a week, on the same day each week. The first four weeks use 2.5 mg (25 units on the syringe). Your clinician then raises the dose in 2.5 mg steps, at least four weeks apart, to the lowest dose that works for you, and does not step up while side effects are active.
Tirzepatide caused thyroid C-cell tumors in rats. Whether that happens in people is not known.
Tell your care team straight away if you feel a lump or swelling in your neck, your voice goes hoarse or swallowing becomes hard, you get severe stomach pain that will not stop, you cannot keep up with vomiting or diarrhea, you get pain in your upper right belly or your eyes turn yellow, or you get a rash with swelling of the face or lips or trouble breathing.
Do not take this if you or a family member has had medullary thyroid carcinoma, you have Multiple Endocrine Neoplasia syndrome type 2, or you have reacted badly to tirzepatide before.
This is not a complete list of side effects. Message your care team about any symptom that worries you. What we dispense is a compounded preparation made by a licensed US pharmacy. Compounded medications are not approved by the FDA for safety, efficacy or quality.
No. Compounded medicines are not FDA approved, and FDA does not review them for safety, effectiveness or quality. Ours is made by a licensed US pharmacy on a clinician's prescription and includes glycine and B12. The trial results on this page are for the branded drug.
Tirzepatide acts on two gut hormone receptors, GIP and GLP-1, while semaglutide acts on GLP-1 only. In a head-to-head trial of the branded drugs, more weight was lost on tirzepatide. That trial was open-label, and stomach side effects were the most common problem on both.
You start at the lowest dose and your clinician raises it in small steps, so the early weeks are about tolerating it. In the main trial the dose stepped up over 20 weeks, and weight kept falling through the 72 weeks.
Usually adults with a BMI of 30 or more, or 27 or more with a weight-related condition, after a clinician reviews their history. It is not for anyone with a personal or family history of medullary thyroid carcinoma or MEN 2.
In the FDA-approved tirzepatide label, nausea affected 25% to 29% of people on the drug and 8% on placebo, with diarrhea, vomiting and constipation next. They are worst after a dose increase. Rare serious effects include pancreatitis and gallbladder disease.
Weight tends to come back. In a trial where people switched to placebo after 36 weeks, they regained an average of 14% of their body weight over the next year, while those who kept going lost more. Plan any change with your clinician.
Not during pregnancy. Tell your clinician if you are pregnant, breastfeeding or planning a pregnancy. If you take birth control pills, the FDA-approved tirzepatide label says to use a non-pill method or add a barrier method for 4 weeks after starting and after each increase.
The clinician review charge is refunded if you are not prescribed, and nothing ships.
$42.25/week · Billed $169 every 4 weeks
