Compounded semaglutide with glycine and B12: a weekly injection that quiets appetite and supports steady weight loss alongside food and movement changes. Prescribed after a licensed clinician reviews your history.
A weekly injection that quiets food noise, with B12 in every dose. Prescribed by US-licensed clinicians.
$39.25/weekBilled $157 every 4 weeks
Medication is charged only if your clinician prescribes it.
Every 28 days
$39.25/week
Free shipping with prescribed treatment.
Today you only pay a $20 clinician review, refunded if you’re not prescribed. Your plan starts only if prescribed.
Prescribed only if appropriate · Compounded medications are not FDA-approved.
14.9%
average weight loss at 68 weeks with semaglutide 2.4 mg, versus 2.4% with lifestyle changes alone
Source: STEP 1, NEJM 202173%
of the 1,961 people in that trial were women
Source: STEP 1, NEJM 2021Weekly
one injection, with the dose stepped up slowly to limit nausea
Source: STEP 1, NEJM 2021Trial of FDA-approved semaglutide 2.4 mg. Compounded semaglutide is not FDA-approved and was not studied. Individual results vary.
Average body weight lost: Day 1 0%, Week 20 10.6%, Week 68 17.4%
Source: Rubino D, et al. STEP 4, JAMA 2021;325(14):1414-25 (branded semaglutide 2.4 mg, continued group) · Group average in a trial of adults who reached the full dose at week 20 and kept taking it. Not a prediction for you.
Less food noise and steady weight loss, with B12 and glycine already in the vial and a clinician who steps your dose up for you.
Licensed clinician review
A US-licensed clinician reads your history, goals and medicines, and prescribes only if semaglutide fits.
Your prescription, filled
Compounded semaglutide with glycine and B12, made by a licensed US pharmacy and sent in 28-day supplies.
Free, discreet shipping
Plain packaging to your door, 2 to 5 business days after approval.
Dose steps built in
Your clinician moves your dose up gradually, at least four weeks apart, and each supply matches your current dose.
Your care team on message
Ask about nausea, appetite or your next step at any point, and your clinician can change the plan.
Tirzepatide on the table too
We offer both medicines, so your clinician can recommend the one that fits your history.
Free lab panel at month 3
Metabolic Check, as a progress check.
“GLP-1s leave me tired, and I don't want to lose muscle.”
B12 and glycine in every dose
Added by the prescriber to help reduce fatigue and muscle loss during weight loss, with nothing extra to buy or remember.
“I'd like numbers, not just the scale.”
No lab visit fee for treatment members
If you want bloodwork to track your progress, book a Quest visit near you without the usual visit fee.
“I don't have time for clinic visits.”
Care from your couch
Assessment, clinician review and refills of your plan happen online, with no waiting room.
Metabolic Check
Weight that won't budge is often hormones and habits, not willpower: appetite signals that stopped working and insulin that has to work harder. Semaglutide copies GLP-1, a hormone your gut releases after eating. It slows how fast your stomach empties and tells your brain you are full, so you eat less without white-knuckling it. Our version adds glycine, to help reduce muscle loss during weight loss, and vitamin B12, to help reduce fatigue and maintain vitamin levels. Those additions were not tested in the trials.
Weight history, goals, health conditions and medicines.
They confirm GLP-1 treatment fits and set a starting dose.
One weekly injection. Your dose rises slowly so your body can adjust.
Your care team helps with side effects and dose changes.
You start at the lowest dose. Hunger and portions often shrink first; the scale can lag.
Your clinician steps the dose up, at least four weeks apart. Nausea is most likely right after a step, and smaller, slower meals help.
Weight keeps coming down. In the semaglutide trial the average kept falling until about week 60.
Weight tends to return if treatment stops, so you and your clinician plan the long game together.
Three things you can do alongside your treatment.
Some lean mass is lost with any weight loss. Protein at every meal and strength training two or more days a week help protect it, and muscle also helps your body clear blood sugar.
In a study of about 7,500 adults, better eating and more activity each shrank visceral fat, and doing both shrank it more. Aim for 150 to 300 minutes of moderate movement a week.
Weight that won't move often traces back to insulin resistance. Our clinicians look at HbA1c (optimal 4.6 to 5.3%), triglycerides (optimal 50 to 80 mg/dL) and vitamin B12 (optimal 545 to 1100 pg/mL).
| Feature | Semaglutide 2.4 mg plus lifestyle | Lifestyle changes alone |
|---|---|---|
| Average weight change at 68 weeks | -14.9% | -2.4% |
| How it is taken | Weekly injection | Diet and activity |
STEP 1 trial of FDA-approved semaglutide 2.4 mg. Compounded semaglutide is not FDA-approved and was not studied in this trial. Individual results vary.
Inject under the skin once a week, on the same day each week. The first four weeks use 0.25 mg (5 units on the syringe). Your clinician then steps the dose up in stages, at least four weeks apart, to the lowest dose that works for you, and holds it if side effects are significant.
Semaglutide caused thyroid C-cell tumors in rodents. Whether that happens in people is not known.
Tell your care team straight away if you feel a lump or swelling in your neck, your voice goes hoarse or swallowing becomes hard, you get severe stomach pain that will not stop, you cannot keep fluids down, you get pain in your upper right belly or your eyes turn yellow, or your face, lips or tongue swell.
Do not take this if you or a family member has had medullary thyroid carcinoma, you have Multiple Endocrine Neoplasia syndrome type 2, or you have reacted badly to semaglutide before.
This is not a complete list of side effects. Message your care team about any symptom that worries you. What we dispense is a compounded preparation made by a licensed US pharmacy. Compounded medications are not approved by the FDA for safety, efficacy or quality.
No. A licensed US pharmacy makes it for you with glycine and B12, and it is not FDA-approved. The FDA does not review compounded drugs for safety, effectiveness or quality before they are dispensed.
Semaglutide works on appetite and fullness whatever your age. Midlife changes in sleep and hormones can make weight harder; your clinician can talk through both.
Nausea is the most common side effect and is most likely as your dose increases. Smaller meals, eating slowly and a slow dose increase help. Tell your care team if it does not settle.
Some lean mass is lost with any weight loss. Eating enough protein and strength training help protect it. Your clinician can guide you.
Appetite usually returns and weight may come back. Plan the next step with your clinician rather than stopping suddenly.
No. Tell your clinician if you are pregnant, breastfeeding or planning a pregnancy; semaglutide should be stopped well before trying to conceive.
$39.25/week · Billed $157 every 4 weeks
