--- title: "Semaglutide + B12, Prescribed Online | Vitals Vault" description: "Injection · 2.5 mg/mL (semaglutide)" canonical: "https://www.vitalsvault.com/treatments/care-semaglutide" last-updated: 2026-08-22 --- # Semaglutide + B12, Prescribed Online | Vitals Vault > Injection · 2.5 mg/mL (semaglutide) [Treatments](https://www.vitalsvault.com/treatments?source=catalog) / Semaglutide + B12 ![Semaglutide + B12 injection package](https://static.vitalsvault.com/treatments/editorial/lane61-care-semaglutide-hero-1200-0467afcf648ece10.webp) # Semaglutide + B12 Injection · 2.5 mg/mL (semaglutide) - Effective weekly GLP-1 therapy - B12 to support daily energy - Cost-friendly compounded option Rated 4.5 stars on Google Choose your plan**Every 28 days**$157 every 4 weeks · Cancel anytime1 vial · semaglutide + B12**$157.00** Free shipping with prescribed treatment. Today you only pay a $20 clinician review, refunded if you’re not prescribed. Your plan starts only if prescribed. Prescribed only if appropriate · Compounded medications are not FDA-approved. [Start as a man](https://www.vitalsvault.com/checkout/medications/app?plan=6fc7157f-1975-58a7-8f02-1f6cdc60d54d&gender=male&flow=payment-first&skipWelcome=true&source=treatments)[Start as a woman](https://www.vitalsvault.com/checkout/medications/app?plan=6fc7157f-1975-58a7-8f02-1f6cdc60d54d&gender=female&flow=payment-first&skipWelcome=true&source=treatments) Cancel anytime · Free shipping · Prescribed only if appropriate US-licensed clinicians Ships from US pharmacies HSA/FSA eligible ![Woman preparing a colorful lunch in her kitchen](https://static.vitalsvault.com/treatments/editorial/vv-womens-weight-benefit-meals-4ddd88c4cbd1d463.webp) ## What is Semaglutide? A GLP-1 agonist that quiets food noise, regulates appetite, and supports gradual, sustained weight loss when paired with lifestyle changes. Our compounded formulation adds B12 to reduce nausea and glycine to help preserve lean muscle. Titrated slowly to the lowest effective dose. ### What to expect - **A starting dose that steps up** Treatment begins low and increases gradually so your body adjusts and side effects stay manageable. - **Appetite changes first** Most people notice reduced appetite and earlier fullness before they notice the scale moving. - **Steady, not sudden** A healthy pace is roughly one to two pounds a week. Faster is not better. - **Nausea is common early** It usually settles within a few weeks and eases with smaller, slower meals. [Get started now](https://www.vitalsvault.com/treatments/care-semaglutide#checkout) ## What you’ll feel as the weight comes off ### Steady fat loss Weight that comes off at a healthy pace. ### Fewer cravings Appetite signals that stop working against you. ### More energy Feeling lighter and more active over time. ### Lasting change Metabolic health you can maintain beyond the scale. ### Your treatment Semaglutide + B12 injection Your prescription confirms the strength, quantity and dispensing schedule. ### Your routine Injected under the skin. Your clinician sets and adjusts your dose. Follow your clinician’s instructions and the pharmacy label. ### Delivered discreetly Free shipping, in discreet packaging. Treatment ships only after your clinician approves a prescription. ### Clinician-guided care A plan reviewed around your health. Your clinician determines whether treatment is appropriate for you. Your selected plan 28-day supply $157 every 4 weeks Prescribed only if appropriate. Billing frequency and shipment quantity may differ; your prescription confirms what is dispensed. ## What the trials measured Drag to your current weight to see the average result from the trials. This is a study average, not a prediction of your result. Your current weight in lb **230 lb**Current weight **35 lb**Average loss over about a year in the trials **196 lb**Where the trial average lands In clinical trials of GLP-1 medications, adults lost a mean of roughly 15 percent of body weight over about a year. STEP 1, semaglutide 2.4 mg, 1,961 adults over 68 weeks, and SURMOUNT-1, tirzepatide over 72 weeks. All participants in both trials also received counselling on diet and physical activity. This is a study average, not a prediction of your personal result, and individual results vary. What is dispensed here is a compounded preparation, made by a licensed US pharmacy. It was not the product studied in those trials, and compounded medications are not approved by the FDA for safety, efficacy or quality. [Read the source](https://pubmed.ncbi.nlm.nih.gov/33567185/) ## How it works ![Online consultation with a licensed clinician](https://static.vitalsvault.com/treatments/editorial/vv-step-clinician-neutral-6719a9b7f7adcdf4.webp) Step 1 ### Online consultation Answer a few health questions — a licensed provider reviews online. No waiting rooms. A few minutes ![Prescription approved](https://static.vitalsvault.com/treatments/editorial/vv-hiw-step3-delivered-v1-2792b7b7fff611e1.webp) Step 2 ### Prescription approved Once approved, your medication ships discreetly to your door. Within 72 hours ![Feeling the difference](https://static.vitalsvault.com/treatments/editorial/6abf4b29e0ac5556476439bd-vv-step-outcome-weight-neutral-f7d6311bab049aca.webp) Step 3 ### Feel the difference Physician-guided support and check-ins keep results on track. 2–5 business days ## How to take it ### How to dose Month 1: 0.2 mg SC once weekly Month 2: 0.4 mg SC once weekly Month 3: 0.9 mg SC once weekly Titrate to lowest effective dose; hold dose if significant GI side effects ## Side effects and safety Semaglutide caused thyroid C-cell tumors in rodents. Whether that happens in people is not known. Tell your care team straight away if you feel a lump or swelling in your neck, your voice goes hoarse or swallowing becomes hard, you get severe stomach pain that will not stop, you cannot keep fluids down, you get pain in your upper right belly or your eyes turn yellow, or your face, lips or tongue swell. ### Common side effects - nausea - diarrhea - vomiting - constipation - abdominal pain - headache - fatigue - dizziness - hair loss ### Rare but serious - acute pancreatitis - gallbladder disease and gallstones - kidney injury from fluid loss - low blood sugar - worsening diabetic eye disease - food left in the stomach during anesthesia Do not take this if you or a family member has had medullary thyroid carcinoma, you have Multiple Endocrine Neoplasia syndrome type 2, or you have reacted badly to semaglutide before. This is not a complete list of side effects. Message your care team about any symptom that worries you. What we dispense is a compounded preparation made by a licensed US pharmacy. Compounded medications are not approved by the FDA for safety, efficacy or quality. ## More in this category ### Tirzepatide + B12 [![Tirzepatide + B12 injection package](https://static.vitalsvault.com/treatments/editorial/6acaeb740a7a70fbdd929b58-lane61-care-tirzepatide-cms-1200-64b40beede961849.webp)](https://www.vitalsvault.com/treatments/care-tirzepatide?audience=men&source=catalog) Injection · 10 mg/mL (tirzepatide) **$229** Billed $229 every 4 weeks [Learn more](https://www.vitalsvault.com/treatments/care-tirzepatide?audience=men&source=catalog) ## Common questions How does semaglutide work? It mimics GLP-1, a hormone your gut releases after eating. That slows stomach emptying and signals fullness to the brain, so you eat less without white-knuckling it. This formulation also includes glycine and B12. How often do I inject? Once weekly, as a small subcutaneous injection you do at home on the same day each week. Your care team walks you through technique. How quickly will I lose weight? Most people see steady loss over months rather than weeks, and the first few weeks are usually about tolerating the dose rather than results. Expect appetite changes before scale changes. What are the common side effects? Nausea, constipation, diarrhoea and reflux are the most common, and are usually worst in the days after a dose increase. Eating smaller portions more slowly helps. Tell your clinician about anything severe or persistent. What happens if I stop? Appetite generally returns and weight regain is common without other changes in place. This is why the habits you build during treatment matter as much as the medication. Who should not take this? It is not appropriate if you have a personal or family history of medullary thyroid carcinoma or MEN 2, and it is not for use in pregnancy. Your intake covers the full list of contraindications. ![Two women browsing flowers at an outdoor market](https://static.vitalsvault.com/treatments/editorial/vv-womens-weight-benefit-life-62475b9cc8acc490.webp) ## Start your plan today $157 every 4 weeks [Start as a man](https://www.vitalsvault.com/checkout/medications/app?plan=6fc7157f-1975-58a7-8f02-1f6cdc60d54d&gender=male&flow=payment-first&skipWelcome=true&source=treatments)[Start as a woman](https://www.vitalsvault.com/checkout/medications/app?plan=6fc7157f-1975-58a7-8f02-1f6cdc60d54d&gender=female&flow=payment-first&skipWelcome=true&source=treatments) ## The clinicians behind your care Your treatment is reviewed and prescribed by US-licensed clinicians in our network. ![Diana Kumar, MD, FACOG](https://static.vitalsvault.com/treatments/editorial/diana-kumar-md-c56d4b361d5774a7.webp) ### Diana Kumar, MD, FACOG Women's hormone health Board certified in obstetrics and gynecology and a Menopause Society Certified Practitioner. Works with members on perimenopause, menopause and hormone therapy. ![William Blackwell, MD](https://static.vitalsvault.com/treatments/editorial/william-blackwell-md-da493dcf19541ad1.webp) ### William Blackwell, MD Weight and metabolic health Board certified in emergency medicine and practicing telehealth since 2018. Focuses on weight management and metabolic health. ![Meenal Kheterpal, MD, FAAD](https://static.vitalsvault.com/treatments/editorial/kheterpal-md-faad-0719a17d75055313.webp) ### Meenal Kheterpal, MD, FAAD Dermatology Board certified dermatologist and Associate Professor of Dermatology at Duke University School of Medicine. Specializes in skin cancer and dermato-oncology. ![Shamail Tariq, MD](https://static.vitalsvault.com/treatments/editorial/shamail-tariq-md-18ac53212de5decd.webp) ### Shamail Tariq, MD Cardiometabolic health Board certified in cardiovascular disease and interventional cardiology. Focuses on preventive cardiology, blood pressure and cholesterol. ![Payel Gupta, MD](https://static.vitalsvault.com/treatments/editorial/payel-gupta-md-761421d304fefc01.webp) ### Payel Gupta, MD Allergy and immunology Triple board certified in allergy and immunology, internal medicine and pediatrics. Clinical instructor at the Icahn School of Medicine at Mount Sinai. --- Canonical HTML: https://www.vitalsvault.com/treatments/care-semaglutide - [llms.txt](https://www.vitalsvault.com/llms.txt) - [sitemap.xml](https://www.vitalsvault.com/sitemap.xml) - [Developer portal](https://www.vitalsvault.com/developers)