For low desire, not erection trouble. Works in the brain, used only when you want it.
$73.17/moBilled $439 every 168 days
Medication is charged only if your clinician prescribes it.
Start with a $20 clinician review
21% to 3%
nausea after the first dose, then after later doses, in the trials of the injected form
Source: Vyleesi prescribing information, section 6.1Not in men
the FDA label says bremelanotide is not indicated in men. Use here is off-label and ours is compounded
Source: Vyleesi prescribing information, section 16 mmHg
largest average rise in systolic blood pressure after a dose, peaking 2 to 4 hours later
Source: Vyleesi prescribing information, section 5.145 min
before sex, as needed. One dose in 24 hours at most, and no more than 8 doses a month
Source: Vyleesi prescribing information, section 2.1Facts from the label of the FDA-approved bremelanotide injection (Vyleesi), which was studied in women. Trials in men have been small and early, and ours is compounded and not FDA approved. Individual results vary.
A desire-first option, screened for your blood pressure and heart health, delivered privately and used only when you choose.
Licensed clinician review
A US-licensed clinician screens your blood pressure, heart history and medicines before prescribing.
Prescription PT-141 injection
Compounded and dispensed by a licensed US pharmacy, in an 84 or 168 day supply.
Free, plain-packaged shipping
Ships 2 to 5 business days after approval.
Care-team messaging
Ask about timing, nausea and dose, and your clinician can adjust your plan.
Free lab panel at month 3
Biological Age Reveal, as a progress check.
“Is this safe for me?”
Screened before you start
Blood pressure and heart history are checked first, and the review fee is refunded if you are not prescribed.
“What if I feel sick?”
A first-dose plan
Your care team helps you time the first dose, the one most likely to cause nausea.
“I do not want to explain this in person.”
No appointment, no waiting room
Questions online, review within 24 hours, vial at your door.
Biological Age Reveal
ED tablets work on blood flow once you are already aroused. PT-141 is a melanocortin receptor agonist, and the receptors it activates sit in the brain as well as the skin. The FDA label says how it improves desire in women is not known, so we do not claim a precise mechanism.
The only large trials were in premenopausal women with low desire, and that is the one FDA-approved use. For men, use is off-label and the research is small and early. Your clinician will say that plainly before prescribing.
Desire is shaped by more than one medicine. Stress, sleep, mood, thyroid, hormones and other medicines all matter, which is why the review starts with your history.
One dose, at least 45 minutes ahead. Used only when you want it, never more than once in 24 hours or eight times in a month.
Your blood pressure, heart history and every medicine you take. No video call, no waiting room.
A few minutes
PT-141 can raise blood pressure for a few hours, so uncontrolled high blood pressure or heart disease rules it out.
Within 24 hours
From a licensed US pharmacy, with free shipping. Keep the vial as the pharmacy label says.
2 to 5 business days
A small injection under the skin of the belly or thigh, at least 45 minutes before sex. Your pharmacy label and care team walk you through the first one.
Ongoing support
Plan it for a quiet evening at home. Nausea is the most common effect and is most likely with this first one.
Inject at least 45 minutes before sex, not at the last minute. You set the mood rather than the clock.
Blood pressure can rise briefly and your heart rate dip slightly. Rest, and message your care team about a severe headache or chest pain.
One dose in 24 hours and no more than 8 a month. If nothing improves after about 8 weeks, talk to your clinician about whether to continue.
Three things you can do alongside your treatment.
Low mood, anxiety, thyroid conditions and some medicines all pull desire down, and low testosterone can too in men. Ask your clinician about checking thyroid and hormones before you rely on any injection.
Chronic stress keeps cortisol high and desire low. Time outdoors, a walk, slow breathing and steady sleep are low-cost ways to shift it.
Long sitting is linked to poorer metabolic health, and strength and movement protect it. More energy and a body that feels like yours is part of wanting sex.
| Feature | PT-141 | Sildenafil | Tadalafil daily |
|---|---|---|---|
| What it targets | Desire, in the brain | Erections, through blood flow | Erections, through blood flow |
| How it is taken | Injection or nasal spray | Tablet | Tablet |
| When | At least 45 minutes before | About 1 hour before | Every day |
| Most common side effects | Nausea, flushing | Headache, flushing | Headache, back ache |
| Status | Compounded, off-label in men | Compounded | Compounded |
All of our versions are compounded by a licensed US pharmacy and are not FDA approved.
Inject 0.1 to 0.175 mL (1 to 1.75 mg) under the skin of the abdomen or thigh, as needed, at least 45 minutes before sex. Your clinician sets your dose; the pharmacy label shows it in units.
Do not use more than one dose in 24 hours, or more than 8 doses a month.
Bremelanotide is FDA approved only for low sexual desire in premenopausal women. The label states it is not indicated in postmenopausal women, not in men, and not to enhance sexual performance.
Tell your care team straight away if your blood pressure climbs or you get a severe headache after a dose, you cannot stop vomiting, you notice new dark patches on your face, gums or breasts, you get chest pain, or your heartbeat becomes very slow.
Common side effects
Rare but serious
Do not take this if you have high blood pressure that is not controlled, or you have known heart disease.
This is not a complete list of side effects. Message your care team about any symptom that worries you. What we dispense is a compounded preparation made by a licensed US pharmacy. Compounded medications are not approved by the FDA for safety, efficacy or quality.
Desire. It is a melanocortin receptor agonist that works on the brain side, not on blood flow. If erections are the main issue, sildenafil or tadalafil are the usual place to start.
No. The FDA-approved bremelanotide is an injection for premenopausal women with low desire, and its label says it is not indicated in men. For men it is prescribed off-label, and ours is compounded by a licensed US pharmacy.
The large trials were in women. The early studies in men were small and used a nasal form, and they are not enough to promise a result. Your clinician explains what that means for you before prescribing.
With a small needle under the skin of the belly or thigh, at least 45 minutes before sex. Your pharmacy label and care team walk you through the first dose.
It is the most common side effect, and it was highest after the first dose in the brand trials. Taking an anti-nausea pill beforehand did not reduce it in a brand study, so plan your first dose for a quiet evening.
Anyone with uncontrolled high blood pressure or known heart disease. It raises blood pressure for a few hours after a dose, which is why we screen first.
There is a nasal spray with the same medicine. It has been studied less than the injection, and some people notice nose irritation.
168-day supply · $73.17/mo · Billed $439 every 168 days
