Desire support, no needle: the same active ingredient as the injection, as a spray (thinner evidence).
$73.17/moBilled $439 every 168 days
Medication is charged only if your clinician prescribes it.
Start with a $20 clinician review
21% to 3%
nausea after the first dose, then after later doses, in the trials of the injected form
Source: Vyleesi prescribing information, section 6.12019
year the FDA approved bremelanotide as an injection, for premenopausal women. The nasal form is not approved
Source: Vyleesi (bremelanotide) prescribing information, section 16 mmHg
largest average rise in systolic blood pressure after an injected dose, peaking 2 to 4 hours later
Source: Vyleesi prescribing information, section 5.145 min
before sex, as needed, per the injected form. One dose in 24 hours at most, and no more than 8 a month
Source: Vyleesi prescribing information, section 2.1Facts from the label of the FDA-approved bremelanotide injection (Vyleesi), studied in premenopausal women. Nothing here was measured on the nasal spray we dispense, which is compounded and not FDA approved. Individual results vary.
A desire-first option with no needle, screened for your blood pressure and heart health, delivered privately and used only when you choose.
Licensed clinician review
A US-licensed clinician screens your blood pressure, heart history and medicines before prescribing.
Prescription PT-141 nasal spray
Compounded and dispensed by a licensed US pharmacy, in an 84 or 168 day supply.
Free, plain-packaged shipping
Ships 2 to 5 business days after approval.
Care-team messaging
Ask about timing, nausea and dose, and your clinician can adjust your plan.
Free lab panel at month 3
Biological Age Reveal, as a progress check.
“I do not want to give myself an injection.”
No needle
One spray in each nostril, nothing to inject.
“Is this safe for me?”
Screened before you start
Blood pressure and heart history are checked first, and the review fee is refunded if you are not prescribed.
“I do not want to explain this in person.”
No appointment, no waiting room
Questions online, review within 24 hours, spray at your door.
Biological Age Reveal
Bremelanotide activates melanocortin receptors, including ones in the brain. The FDA label says how it improves desire in women is not known, so we do not claim a precise mechanism. It is a different route from ED tablets, which work on blood flow.
The large trials used an injection in premenopausal women, and that is the only FDA-approved form. Our nasal spray gives the same medicine by a different route. Early studies of a nasal form were small, so we say plainly that the evidence for the spray is thinner.
Desire is shaped by more than one medicine. Stress, sleep, mood, thyroid, hormones and other medicines all matter, which is why the review starts with your history.
One spray, at least 45 minutes ahead. The same medicine without an injection. Never more than one dose in 24 hours.
Your blood pressure, heart history and every medicine you take. No video call, no waiting room.
A few minutes
PT-141 can raise blood pressure for a few hours, so uncontrolled high blood pressure or heart disease rules it out.
Within 24 hours
From a licensed US pharmacy, with free shipping. Store it as the pharmacy label says.
2 to 5 business days
One spray in each nostril, at least 45 minutes before sex. Plan the first one for a quiet evening.
Ongoing support
Plan it for a quiet evening at home. Nausea is the most common effect and is most likely with this first one.
Use it at least 45 minutes before sex, not at the last minute. You set the mood rather than the clock.
Blood pressure can rise briefly and your heart rate dip slightly. Rest, and message your care team about a severe headache or chest pain.
One dose in 24 hours and no more than 8 a month. If nothing improves after about 8 weeks, talk to your clinician about whether to continue.
Three things you can do alongside your treatment.
Low mood, anxiety, thyroid conditions and some medicines all pull desire down, and low testosterone can too in men. Ask your clinician about checking thyroid and hormones first.
Chronic stress keeps cortisol high and desire low. Time outdoors, a walk, slow breathing and steady sleep are low-cost ways to shift it.
Long sitting is linked to poorer metabolic health, and strength and movement protect it. More energy and a body that feels like yours is part of wanting sex.
| Feature | PT-141 nasal spray | PT-141 injection |
|---|---|---|
| How it is given | One spray in each nostril | A small injection under the skin |
| Dose | 2 mg per dose | 1 to 1.75 mg, set by your clinician |
| Timing | At least 45 minutes before sex | At least 45 minutes before sex |
| Evidence | Studied in small, early trials only | The label trials used the injected form |
| Extra side effect | Nose irritation | A reaction where you inject |
Both are compounded by a licensed US pharmacy and are not FDA approved. Both share the same limits: one dose in 24 hours, up to 8 a month.
Spray once in each nostril (2 mg total) at least 45 minutes before sex. Do not use more than one dose in 24 hours, or more than 8 doses a month.
Bremelanotide is FDA approved only for low sexual desire in premenopausal women. The label states it is not indicated in postmenopausal women, not in men, and not to enhance sexual performance.
Tell your care team straight away if your blood pressure climbs or you get a severe headache after a dose, you cannot stop vomiting, you notice new dark patches on your face, gums or breasts, you get chest pain, or your heartbeat becomes very slow.
Common side effects
Rare but serious
Do not take this if you have high blood pressure that is not controlled, or you have known heart disease.
This is not a complete list of side effects. Message your care team about any symptom that worries you. What we dispense is a compounded preparation made by a licensed US pharmacy. Compounded medications are not approved by the FDA for safety, efficacy or quality.
Same medicine, same limits. Choose the spray if you would rather avoid needles. The injection has been studied more, and it is the form used in the brand trials. Your clinician can help you choose.
No. The FDA-approved bremelanotide is an injection for premenopausal women with low desire. Ours is a compounded nasal spray from a licensed US pharmacy, and any other use is off-label.
One spray in each nostril, at least 45 minutes before sex, no more than once in 24 hours and no more than 8 times a month.
The label trials used the injection. Early studies of a nasal form in men were small, and the nasal spray we dispense has not been through a phase 3 trial. Your clinician explains this before prescribing.
Nausea is the most common, along with flushing, headache and some nose irritation. Taking an anti-nausea pill beforehand did not reduce nausea in a brand study.
Follow the pharmacy label. Compounded sprays come with a use-by date.
168-day supply · $73.17/mo · Billed $439 every 168 days
