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Free lab panel at month 3Start by Jan 31
NAD+ 200 mg/mL injection vial package

4.5 on Google

NAD+ Injection

Injection · 200 mg/mL

A start-low, build-up NAD+ injection with clinician oversight. The human evidence is still early.

$62.50/weekBilled $250 every 4 weeks

Start my $20 doctor visit

Medication is charged only if your clinician prescribes it.

Free lab panel with your treatment Start by Jan 31

Biological Age Reveal

Given at your 3-month mark as a progress check.

  • US clinicians
  • Licensed pharmacy
  • LegitScript
  • $20 review refunded
  • Free discreet shipping
  • Start-low, step-up dosing set by a clinician
  • NAD+ 200 mg/mL from a licensed US pharmacy
  • A few small injections a week at home

28-day supply

$62.50/week

Billed $250 every 4 weeks · Cancel anytime

  • Injection · 200 mg/mL
  • Free, discreet shipping
  • Prescribed only if appropriate

Start with a $20 clinician review

The review fee is refunded if you’re not prescribed. Medication is billed separately only if prescribed.

Start my $20 doctor visit

Prescribed only if appropriate. Compounded medications are not FDA-approved. Review the full terms in checkout.

What the research shows

  • 19 trials

    Meta-analysis: NAD+ precursors lowered total cholesterol and triglycerides, with no clear effect on other outcomes

    Source: Oliveira-Cruz A, et al. Horm Metab Res 2024;56(11):818-26 (meta-analysis of randomized trials)
  • 412 adults

    In 9 randomized trials pooled, NMN modestly improved gait speed, ALT and insulin resistance in older adults

    Source: Wang JP, et al. Curr Pharm Biotechnol 2025;26(13):2141-52 (meta-analysis of randomized trials)
  • No muscle gain

    NMN and NR did not improve muscle mass or strength in adults over 60, in a 2025 meta-analysis of randomized trials

    Source: Prokopidis K, et al. J Cachexia Sarcopenia Muscle 2025;16(3):e13799 (meta-analysis of randomized trials)

These are trials of oral NAD+ precursors (NMN and NR), not NAD+ injections. We found no published randomized trial of subcutaneous NAD+, so the evidence for the injection itself is still early. Ours is compounded and not FDA approved. Individual results vary.

NAD+ 200 mg/mL injection vial package

The Start-Low NAD+ Protocol

Support your cells' NAD+ pathway with a dose that starts low and steps up only as far as you need, guided by a clinician who is straight about the evidence.

Everything included

  • Licensed clinician review

    A US-licensed clinician reviews your health history, medicines and goals, and prescribes only if NAD+ fits.

  • Compounded NAD+, 200 mg/mL

    A 10 mL vial from a licensed US pharmacy. One fill is a 28-day supply.

  • A built-in step-up schedule

    Start at 25 units (50 mg) and build by 25 units every 2 weeks as tolerated, up to the lowest dose that works for you.

  • Free, discreet shipping

    2 to 5 business days after your clinician approves a prescription.

  • Care-team messaging

    Message your care team about flushing, nausea or dose. Your clinician adjusts the schedule as you go.

Bonuses

  • Free lab panel at month 3

    Biological Age Reveal, as a progress check.

  • “What if it hits me too hard?”

    Slow-build dosing

    The directions start low and add dose only every 2 weeks, so you find your level without jumping in.

  • “Is this proven?”

    The evidence, stated plainly

    Your clinician and this page tell you what is and is not proven, before you start.

NAD+ 200 mg/mL injection vial package

28-day supply

$62.50/week

Billed $250 every 4 weeks

  • $20 review refunded if not prescribed
  • Cancel anytime

Free, discreet shipping

Start my $20 doctor visit

Start today: your clinician reviews within 24 hours, and your vial ships 2 to 5 business days after approval.

Labs we cover

Biological Age Reveal

  • CMP
  • CBC with differential
  • hs-CRP
  • Biological age score

Start or transfer your treatment between Nov 1 and Jan 31 and get this panel free at your 3-month mark. Labs are a bonus, not needed to start treatment.

From questions to your first dose

NAD+ is a coenzyme in every cell. Mitochondria use it to turn food into energy, and repair enzymes use it to fix DNA. In human tissue studies, NAD+ levels fall with age as oxidative damage rises.

What we do not know is whether injecting it helps. Most human trials use oral precursors such as NMN or NR, and results are mixed. We found no published randomized trial of subcutaneous NAD+, so your clinician starts low, steps up slowly and checks how you respond.

A small injection at home, a few times a week. You start on a low dose and build up every two weeks, only as far as you are comfortable.

  1. 1
    Step 1
    Messaging the care team from home

    Answer a few questions

    Tell us about your health, your medicines and what you want from NAD+. It takes a few minutes online.

  2. 2
    Step 2
    A Middle Eastern woman in her late 30s with long dark hair on a video visit with her clinician at home

    A clinician reviews your answers

    They prescribe only if NAD+ fits, and they tell you plainly what the evidence does and does not show. Reviewed within 24 hours.

  3. 3
    Step 3
    A white woman in her late 50s with short silver hair opening a plain delivery box at home while talking with her clinician

    Your vial ships from a US pharmacy

    If prescribed, your compounded NAD+ ships free in discreet packaging in 2 to 5 business days.

  4. 4
    Step 4
    A Black man in his early 40s with a short beard on a video visit with his clinician at home

    Adjust as you go

    You start at 25 units twice a week and your clinician builds the dose every 2 weeks, only as far as you need.

A man cycling by the sea with a basket

What to expect

  1. 01

    Weeks 1 and 2

    You start at 25 units (50 mg) twice a week. Injecting slowly helps limit flushing.

  2. 02

    Every 2 weeks

    Your clinician can raise the dose by 25 units as tolerated, to the lowest dose that works for you.

  3. 03

    Warmth or flushing

    Commonly reported, short-lived and usually mild. Tell your care team if chest tightness or nausea does not settle.

  4. 04

    Early evidence

    No published randomized trial tests NAD+ injections, and trials of oral precursors are mixed. Responses vary widely.

  5. 05

    Wellness, not treatment

    This supports cellular energy. It does not treat a diagnosed condition.

What makes it work better

Three things you can do alongside your treatment.

  1. An older couple cycling along the seaside
    01

    Move your mitochondria

    Exercise is one of the lifestyle factors that shape how well your mitochondria work. Regular training and walking are the base everything else sits on.

  2. Clear, rested skin in natural light
    02

    Protect sleep and recovery

    Sleep, stress and exposure to pollutants all affect how your cells make energy. Steady sleep and stress habits do more for fatigue than any single supplement.

  3. A woman eating a plate of salmon, greens, avocado, quinoa and berries at home
    03

    Feed mitochondria with food

    A Mediterranean-style, plant-rich diet with fish, magnesium-rich foods and B vitamins supports mitochondrial function. We check B12 and methylmalonic acid because a shortfall in B12 can mimic low energy.

NAD+ injection, oral precursors or IV

FeatureOur NAD+ injectionOral NMN or NRIV NAD+ at a clinic
How it worksNAD+ itself, injected under the skinRaw materials your body converts into NAD+NAD+ itself, infused into a vein
Human evidenceNo published randomized trial that we could findRandomized trials show NAD+ metabolites rise; effects on muscle and metabolism are mixedNot established for energy or aging
FormatA few small injections a week at homeA capsule or powder every dayScheduled sessions at a clinic
DosingStarts at 25 units and steps up every 2 weeks as toleratedFixed supplement dosesSet by the infusion clinic
Regulatory statusCompounded, not FDA approved; prescribed only if appropriateSold as supplementsCompounded or supplement-grade; not FDA approved for energy or aging

No head-to-head trial compares these routes. Your clinician helps you choose.

Before you start

  • Tell your clinician about heart conditions, any history of cancer, and pregnancy or breastfeeding. NAD+ injections have not been studied in these settings.
  • List every medicine and supplement you take, including NMN, NR or niacin.
  • Inject slowly. Flushing is the most commonly reported sensation, and your clinician can slow the pace of the build-up.
  • NAD+ here is compounded by a licensed US pharmacy and is not FDA approved. It is prescribed only if it is right for you.

How to take it

Inject 25 units (50 mg) subcutaneously once or twice weekly for 2 weeks, then increase by 25 units every 2 weeks to the minimum effective dose as tolerated (absolute maximum 100 units per dose), up to 3 times a week for maintenance. Discard any remaining medication 28 days after the first puncture.

Side effects and safety

There is no FDA approved NAD product for injection or infusion, so there is no FDA reviewed safety label for it and no established side effect rate. It has not been approved for energy, focus, recovery or aging.

Tell your care team straight away if you get chest tightness, shortness of breath, flushing with a pounding heartbeat after an injection, nausea you cannot settle, or a rash or swelling.

This is not a complete list of side effects. Message your care team about any symptom that worries you. What we dispense is a compounded preparation made by a licensed US pharmacy. Compounded medications are not approved by the FDA for safety, efficacy or quality.

Your questions, answered.

A Latina woman in her mid 50s with wavy dark hair reading a message from her care team
What is NAD+ and why do people want more of it?+

NAD+ is a coenzyme in every cell. Your mitochondria use it to turn food into energy and repair enzymes use it to fix DNA. In human tissue studies, NAD+ levels fall with age, which is why it appears in healthy-aging protocols.

Is there proof that NAD+ injections work?+

Not yet. We found no published randomized trial of subcutaneous NAD+. Meta-analyses of oral precursors such as NMN and NR show mixed results, with small gains in some measures and none in others. We offer it as clinician-guided wellness support, and we say so plainly.

Why inject NAD+ instead of taking NMN or NR pills?+

Pills supply raw materials your body must convert, while the injection supplies NAD+ itself. No head-to-head trial shows one route works better, so the reason to choose injection is preference and clinician guidance, not proven superiority.

How is my dose set?+

The directions start at 25 units (50 mg) once or twice a week for 2 weeks. Your clinician then raises it by 25 units every 2 weeks to the lowest dose that works for you, up to 100 units a dose and up to 3 times a week.

What will I feel?+

Warmth or flushing around dosing is commonly reported and short-lived, and injecting slowly helps. Any change in energy or focus varies from person to person. Tell your care team about chest tightness, nausea that will not settle, a rash or swelling.

Which labs do you look at?+

Labs are not required to start. If you have them, useful markers are B12 and methylmalonic acid, hs-CRP, hemoglobin A1C, hemoglobin and iron. The optimal ranges our clinicians use include hs-CRP up to 3 mg/L, hemoglobin A1C of 4.6 to 5.3 percent and methylmalonic acid at or below 260 nmol/L.

How long does a vial last?+

A 10 mL vial of 200 mg/mL is a 28-day supply. The pharmacy label says to discard any remaining medication 28 days after the first puncture.

Is it approved, and is it safe?+

No NAD+ injection is FDA approved, so there is no FDA safety label and no established side effect rate. It has not been approved for energy, focus, recovery or aging. What we dispense is compounded by a licensed US pharmacy, and compounded medicines are not reviewed by the FDA for safety, efficacy or quality.

The Start-Low NAD+ Protocol

  • Reviewed by a US-licensed clinician, and prescribed only if it suits you
  • Filled by a licensed US pharmacy
  • Free, discreet shipping to your door
  • LegitScript certified, and rated 4.5 on Google

28-day supply · $62.50/week · Billed $250 every 4 weeks

Start my $20 doctor visit
  • $20 review refunded if not prescribed
  • Cancel anytime
  • Free, discreet shipping
A white man in his late 50s with close-cropped grey hair on a video visit with his clinician at home

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$62.50/week

Billed $250 every 4 weeks

Start $20 visit