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Women/Explore care/Liothyronine
Free lab panel at month 3Start by Jan 31
Liothyronine T3 product image

4.5 on Google

Liothyronine

Tablet · 5 mcg

Liothyronine (T3), added by your clinician when levothyroxine alone isn't enough.

$1.30/dayBilled $78 every 60 days

Start my $20 doctor visit

Medication is charged only if your clinician prescribes it.

Free lab panel with your treatment Start by Jan 31

Thyroid Check

Given at your 3-month mark as a progress check.

  • US clinicians
  • Licensed pharmacy
  • $20 review refunded
  • Free discreet shipping
  • Labs clinician-reviewed
  • Active thyroid hormone (T3)
  • An add-on when T4 alone is not enough
  • Dose set from your thyroid panel

Required lab testing

RX-T3 Panel · $79.00

See the 7 tests included

Thyroid Stimulating Hormone (TSH), Free T4, Free T3, Total T3, Reverse T3, Thyroid Peroxidase Antibodies (TPO), Thyroglobulin Antibodies

Required before your first order. Your clinician reviews thyroid labs when prescribing liothyronine. Upload a recent report or order this panel; you can do this after checkout.

RX-T3 Panel: results within 90 days.

Already have results?

Upload your results after you start. Your care team confirms whether they meet the testing requirements. Buying a panel or uploading a file does not by itself satisfy a required test.

Panel prices and any applicable lab visit fees are confirmed in checkout.

60-day supply

$1.30/day

Billed $78 every 60 days · Cancel anytime

  • Tablet · 5 mcg
  • Free, discreet shipping
  • Prescribed only if appropriate

Start with a $20 clinician review

The review fee is refunded if you’re not prescribed. Medication is billed separately only if prescribed.

Start my $20 doctor visit

Prescribed only if appropriate. Compounded medications are not FDA-approved. Review the full terms in checkout.

What the research shows

  • 5 in 100

    Americans aged 12 and over have hypothyroidism; women are much more likely than men

    Source: NIDDK, hypothyroidism

  • Add-on

    guidelines find insufficient evidence for routine T4 plus T3; it is a shared decision

    Source: ATA guidelines, Thyroid 2014

  • 6-8 weeks

    after any dose change, your TSH is rechecked

    Source: Synthroid label (DailyMed)

Individual results vary.

Liothyronine T3 product image

The Thyroid Fine-Tune Plan

A clinician-checked T3 add-on, started low and adjusted from timed labs, with your care team a message away.

Everything included

  • Clinician review of your full thyroid panel

    TSH, T4, T3, reverse T3 and antibodies read alongside your symptoms and current levothyroxine.

  • Liothyronine from a licensed US pharmacy

    A 60-day supply of 5 mcg tablets; your clinician sets the schedule.

  • Free, discreet shipping

    Ships 2 to 5 business days after approval.

  • Labs before every refill

    Timed bloodwork keeps the dose matched to you.

  • Care team messaging

    Report racing heart, tremor or poor sleep and your clinician can change the dose.

  • Results stored in your Vault

    Every panel in one place, so you can compare T3, reverse T3 and TSH across checks.

Bonuses

  • Free lab panel at month 3

    Thyroid Check, as a progress check.

  • “I already paid for these tests.”

    Use the labs you already have

    Upload a recent panel; your care team confirms whether it meets the requirement.

  • “Is this just upselling me another pill?”

    No add-on pressure

    Your clinician can decide T3 is not right and keep you on levothyroxine alone, and the review is refunded if you are not prescribed.

Liothyronine T3 product image

60-day supply

$1.30/day

Billed $78 every 60 days

  • $20 review refunded if not prescribed
  • Cancel anytime
  • Full refund before your blood draw

Free, discreet shipping

Start my $20 doctor visit

Start today: your clinician reviews within 24 hours, and tablets ship 2 to 5 business days after approval.

Labs we cover

Thyroid Check

  • TSH
  • Free T4

Start or transfer your treatment between Nov 1 and Jan 31 and get this panel free at your 3-month mark, as a bonus progress check.

How it works

Your body makes most of its active T3 by converting T4. For most people with hypothyroidism, levothyroxine alone restores enough T3 and symptoms settle.

For some people, symptoms continue even with a TSH in range. Your clinician reviews your full panel and may add a small dose of liothyronine, which is T3 itself. Guidelines treat this as a shared decision rather than a routine step.

One small tablet a day. Some members move to twice a day after follow-up labs. Labs are checked before every refill.

  1. 1
    Step 1
    Woman walking home from a neighborhood market

    Start with your labs

    A thyroid panel at a lab near you, or upload recent results.

  2. 2
    Step 2
    Woman writing in her journal beside a window

    A clinician reviews

    They review your T4 treatment, symptoms and labs before adding T3.

  3. 3
    Step 3
    Two women enjoying a conversation in a park

    Small, timed doses

    T3 is short-acting, so it may be split through the day.

  4. 4
    Step 4

    Recheck and fine-tune

    Timed blood tests guide the dose.

Woman reading a book in her living room

What to expect

  1. 01

    Start low

    Your clinician starts with a small dose and steps up in small increments.

  2. 02

    Split doses

    T3 is short acting, so it is often taken twice a day on a set schedule.

  3. 03

    Watch for overshoot

    A racing heart, tremor, anxiety or poor sleep can mean the dose is too high. Message your care team.

  4. 04

    Labs before refills

    Bloodwork is timed relative to your dose and checked before every refill.

What makes it work better

Three things you can do alongside your treatment.

  1. Out walking in the sun, full of energy
    01

    Check the conversion step

    Selenium and zinc help your body turn T4 into active T3, and a healthy gut supports that process. Food comes first, and your clinician advises on any supplement.

  2. Woman reviewing a private health intake at home
    02

    Look at what is steering T4 away from T3

    Illness, stress, very low calories and inflammation can push T4 toward inactive reverse T3. Reading free T3, reverse T3 and their ratio shows whether that is happening.

  3. Messaging the care team from home
    03

    Protect sleep and recovery

    Poor sleep and chronic stress are linked with shifts in thyroid hormone. A regular sleep schedule and a calmer evening routine help T3 do its job.

T4 alone or T4 plus T3?

FeatureT4 + T3T4 alone
Standard first treatmentNo, an add-onYes
Who it is forSome people who still have symptoms on T4Most people with hypothyroidism
DosingOften split dosesOnce daily

Guidelines find insufficient evidence for routine combination therapy, so T3 is a shared decision with your clinician.

Before you start

  • For adults with diagnosed hypothyroidism, usually already on levothyroxine.
  • Tell your clinician right away if you are pregnant or become pregnant, because thyroid hormone needs change and TSH is checked in each trimester.
  • Stop biotin and any supplement that contains it at least 2 days before thyroid blood tests, because it can distort the result.
  • Draw blood at the time your clinician asks, relative to your dose, because T3 levels move within hours.
  • Tell your clinician about heart rhythm problems, chest pain, diabetes or untreated adrenal insufficiency.

How to take it

Take 1 tablet (5 mcg) by mouth daily; may titrate to 5 mcg twice daily based on follow-up labs

Side effects and safety

Thyroid hormone must not be used for weight loss. Doses larger than your body needs can be dangerous, especially alongside other weight loss medication.

Tell your care team straight away if you get chest pain, a pounding or racing or irregular heartbeat, shortness of breath, tremor or sweating or feeling overheated, or you lose weight without meaning to and cannot sleep.

Common side effects

  • palpitations
  • a fast heart rate
  • tremor
  • muscle weakness
  • headache
  • nervousness
  • insomnia
  • diarrhea
  • feeling too warm

Rare but serious

  • heart rhythm problems, particularly if you are older or have heart disease
  • worsening angina or heart attack
  • adrenal crisis if adrenal insufficiency has not been corrected first
  • loss of bone mineral density with long term over-replacement
  • loss of blood sugar control if you have diabetes

Do not take this if you have adrenal insufficiency that has not been treated first.

This is not a complete list of side effects. Message your care team about any symptom that worries you.

Your questions, answered.

A white woman in her late 40s with shoulder-length auburn hair reading a message from her care team
When is T3 added?+

When symptoms continue on levothyroxine despite labs in range and other causes have been checked.

Does everyone need T3?+

No. Most people do well on levothyroxine alone. Guidelines do not recommend combination therapy routinely.

How is it dosed?+

Small doses, often once or twice a day on a set schedule, adjusted from labs.

What should I watch for?+

A racing heart, tremor, anxiety or poor sleep can mean the dose is too high. Tell your care team.

Will it help me lose weight?+

No. Thyroid hormone must not be used for weight loss.

How is it monitored?+

Blood tests timed relative to your dose, usually 6 to 8 weeks after a change.

The Thyroid Fine-Tune Plan

  • Reviewed by a US-licensed clinician, and prescribed only if it suits you
  • Filled by a licensed US pharmacy
  • Free, discreet shipping to your door
  • LegitScript certified, and rated 4.5 on Google

60-day supply · $1.30/day · Billed $78 every 60 days

Start my $20 doctor visit
  • $20 review refunded if not prescribed
  • Cancel anytime
  • Full refund before your blood draw
  • Free, discreet shipping
An East Asian man in his mid 40s opening a plain delivery box at home while talking with his clinician

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$1.30/day

Billed $78 every 60 days

Start $20 visit