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Women/Explore care/Levothyroxine
Free lab panel at month 3Start by Jan 31
Levothyroxine tablet pack

4.5 on Google

Levothyroxine

For people already prescribed levothyroxine by their doctor. Tablet · 50 mcg (25-100 mcg range)

Thyroid care guided by your labs: levothyroxine, the standard treatment for an underactive thyroid.

$1.39/dayBilled $125 every 90 days

Start my $20 doctor visit

Medication is charged only if your clinician prescribes it.

Free lab panel with your treatment Start by Jan 31

Thyroid Check

Given at your 3-month mark as a progress check.

  • US clinicians
  • Licensed pharmacy
  • $20 review refunded
  • Free discreet shipping
  • Labs clinician-reviewed
  • The standard treatment for hypothyroidism
  • Dose checked against your TSH and free T4
  • One tablet each morning, before food

Required lab testing

TSH + Free T4 · $30.99

See the 2 tests included

TSH, Free T4

Required before your first order.

TSH + Free T4: results within 90 days.

Optional lab recommendations

These are recommendations, not additional required tests.

RX-T3 Panel · $79.00

See the 7 tests included

Thyroid Stimulating Hormone (TSH), Free T4, Free T3, Total T3, Reverse T3, Thyroid Peroxidase Antibodies (TPO), Thyroglobulin Antibodies

Recommended for your care.

For this recommendation, results within 90 days can be reviewed.

Already have results?

Upload your results after you start. Your care team confirms whether they meet the testing requirements. Buying a panel or uploading a file does not by itself satisfy a required test.

Panel prices and any applicable lab visit fees are confirmed in checkout.

90-day supply

$1.39/day

Billed $125 every 90 days · Cancel anytime

  • For people already prescribed levothyroxine by their doctor. Tablet · 50 mcg (25-100 mcg range)
  • Free, discreet shipping
  • Prescribed only if appropriate

Start with a $20 clinician review

The review fee is refunded if you’re not prescribed. Medication is billed separately only if prescribed.

Start my $20 doctor visit

Prescribed only if appropriate. Compounded medications are not FDA-approved. Review the full terms in checkout.

What the research shows

  • 5 in 100

    Americans aged 12 and over have hypothyroidism; women are much more likely than men

    Source: NIDDK, hypothyroidism

  • Empty stomach

    one tablet each morning, 30 to 60 minutes before breakfast, per the label

    Source: Synthroid label (DailyMed)

  • 6-8 weeks

    after any dose change, your TSH is rechecked

    Source: Synthroid label (DailyMed)

Individual results vary.

Levothyroxine tablet pack

The Steady Thyroid Plan

Your levothyroxine, dosed from your own TSH and free T4 and rechecked after every change, delivered to your door.

Everything included

  • Clinician review of your labs and history

    A US-licensed clinician reads TSH, free T4, symptoms and your current dose before prescribing.

  • Levothyroxine from a licensed US pharmacy

    A 90-day supply of the 50 mcg tablet; your clinician sets the strength.

  • Free, discreet shipping

    Ships 2 to 5 business days after approval.

  • Care team messaging

    Ask about symptoms or dose changes any time; your clinician can adjust the plan.

  • Recheck guidance

    TSH timing set by the label: 6 to 8 weeks after a change, then every 6 to 12 months once stable.

  • Results stored in your Vault

    Every result stays in one place, so you can see TSH settle over time.

Bonuses

  • Free lab panel at month 3

    Thyroid Check, as a progress check.

  • “I do not want another blood draw.”

    Use the labs you already have

    Upload recent results and your care team confirms whether they meet the requirement.

  • “What if my dose turns out to be wrong?”

    Dose changes by message

    Message your care team if something feels off and your clinician can adjust the plan.

Levothyroxine tablet pack

90-day supply

$1.39/day

Billed $125 every 90 days

  • $20 review refunded if not prescribed
  • Cancel anytime
  • Full refund before your blood draw

Free, discreet shipping

Start my $20 doctor visit

Start today: your clinician reviews within 24 hours, and tablets ship 2 to 5 business days after approval.

Labs we cover

Thyroid Check

  • TSH
  • Free T4

Start or transfer your treatment between Nov 1 and Jan 31 and get this panel free at your 3-month mark, as a bonus progress check.

How it works

Your thyroid makes T4, and your tissues convert it into active T3. When the gland cannot keep up, as in Hashimoto's thyroiditis or after thyroid surgery or radioactive iodine, energy, temperature and mood can all slow down.

Levothyroxine is the same T4 your thyroid would make. Taken every morning on an empty stomach, it tops up the missing hormone, and your clinician adjusts the dose using TSH and free T4 so you land in a steady range.

One tablet each morning, before breakfast. Take it on an empty stomach, 30 to 60 minutes before food. Your TSH is rechecked 6 to 8 weeks after any change.

  1. 1
    Step 1
    Woman walking home from a neighborhood market

    Get your labs

    TSH and free T4 at a lab near you, or upload recent results.

  2. 2
    Step 2
    A couple sitting together on terrace steps

    A clinician reviews

    They look at your labs, symptoms and history together.

  3. 3
    Step 3
    Winding down with tea at bedtime

    One tablet each morning

    On an empty stomach, 30 to 60 minutes before food.

  4. 4
    Step 4

    Recheck and fine-tune

    Labs about 6 to 8 weeks after a change until your dose is right.

Out walking in the sun, full of energy

What to expect

  1. 01

    Weeks 1 to 2

    Some people notice small changes early. The full effect of a dose builds more slowly, over about 4 to 6 weeks.

  2. 02

    Weeks 6 to 8

    Your TSH is rechecked 6 to 8 weeks after any dose change, because that is when levels settle.

  3. 03

    Once stable

    Checks move to every 6 to 12 months, or sooner if your health, weight or medicines change.

  4. 04

    Any time

    Pregnancy, a big weight change or a new medicine can change your dose. Tell your care team early.

What makes it work better

Three things you can do alongside your treatment.

  1. A couple out cycling by the sea
    01

    Find the cause, not only the number

    Hashimoto's thyroiditis, an autoimmune attack on the gland, is the most common cause of hypothyroidism. TPO and thyroglobulin antibodies show whether it is driving your levels, so your plan fits the cause.

  2. Two people stretching outdoors
    02

    Feed the conversion

    Iodine and iron are needed to build thyroid hormone, and selenium and zinc help convert T4 into active T3. Food comes first; ask your clinician before adding supplements.

  3. Woman writing in her journal beside a window
    03

    Lower the load on your thyroid

    Chronic stress, poor sleep and ongoing inflammation are all linked with changes in thyroid hormone. A steady sleep schedule, regular movement and a stress outlet help your medication do its job.

A test kit or lab-guided care?

FeatureVitals Vault thyroid careAt-home test only
Thyroid labsYesYes
Clinician reviews results with symptomsYesUsually a report only
Prescription if appropriateYesNo
Dose rechecksBuilt inUp to you

Before you start

  • For adults already diagnosed with an underactive thyroid and prescribed levothyroxine by a physician.
  • Tell your clinician right away if you are pregnant or become pregnant. Dose needs often rise, and TSH is checked in each trimester.
  • Stop biotin and any supplement that contains it at least 2 days before a TSH or T4 blood test, because it can distort the result.
  • Keep calcium, iron, magnesium and antacids at least 4 hours away from your dose.
  • Tell your clinician about heart disease, diabetes or adrenal insufficiency that has not been treated.

How to take it

Take 1 tablet by mouth every morning on empty stomach, 30-60 minutes before food; dose adjusted on TSH/Free T4 at 6-8 weeks

Side effects and safety

Thyroid hormone must not be used for weight loss. Doses larger than your body needs can be dangerous, especially alongside other weight loss medication.

Tell your care team straight away if you get chest pain, a pounding or racing or irregular heartbeat, shortness of breath, tremor or sweating or feeling overheated, or you lose weight without meaning to and cannot sleep.

Common side effects

  • palpitations
  • a fast heart rate
  • tremor
  • muscle weakness
  • headache
  • nervousness
  • insomnia
  • diarrhea
  • feeling too warm

Rare but serious

  • heart rhythm problems, particularly if you are older or have heart disease
  • worsening angina or heart attack
  • adrenal crisis if adrenal insufficiency has not been corrected first
  • loss of bone mineral density with long term over-replacement
  • loss of blood sugar control if you have diabetes

Do not take this if you have adrenal insufficiency that has not been treated first.

This is not a complete list of side effects. Message your care team about any symptom that worries you.

Your questions, answered.

Messaging the care team from home
My labs are normal but I still feel tired. Can you help?+

Your clinician looks at symptoms alongside labs. If thyroid treatment is not right, they can talk through other causes such as iron, sleep or perimenopause.

Could this be my thyroid or menopause?+

They share symptoms such as tiredness, mood and weight change. A TSH test helps tell them apart.

How should I take it?+

Every morning on an empty stomach with water, 30 to 60 minutes before food. Keep calcium, iron and antacids at least 4 hours apart.

Will it help me lose weight?+

No. Thyroid hormone must not be used for weight loss, and extra doses can be dangerous. Treating a low thyroid can help symptoms like tiredness and feeling cold.

How long until I feel better?+

It takes about 6 to 8 weeks to reach a steady level, which is when labs are rechecked. Dose adjustments are normal.

Is it safe in pregnancy?+

Levothyroxine is used in pregnancy, but dose needs often change. Tell your clinician right away if you become pregnant.

The Steady Thyroid Plan

  • Reviewed by a US-licensed clinician, and prescribed only if it suits you
  • Filled by a licensed US pharmacy
  • Free, discreet shipping to your door
  • LegitScript certified, and rated 4.5 on Google

90-day supply · $1.39/day · Billed $125 every 90 days

Start my $20 doctor visit
  • $20 review refunded if not prescribed
  • Cancel anytime
  • Full refund before your blood draw
  • Free, discreet shipping
An East Asian woman in her early 40s with a bob opening a plain delivery box at home while talking with her clinician

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$1.39/day

Billed $125 every 90 days

Start $20 visit