Keep your thyroid levels steady: levothyroxine from a US pharmacy, dosed from your TSH and free T4.
$1.39/dayBilled $125 every 90 days
Medication is charged only if your clinician prescribes it.
90-day supply
$1.39/day
Start with a $20 clinician review
Nearly 5 in 100
Americans aged 12 and over have hypothyroidism, and most cases are mild or cause few obvious symptoms
Source: NIDDK, Hypothyroidism (underactive thyroid)Standard of care
The American Thyroid Association says levothyroxine should remain the standard treatment for hypothyroidism
Source: Jonklaas J, et al. Thyroid 2014;24(12):1670-1751 (ATA guideline)6 to 8 weeks
The label says to recheck TSH 6 to 8 weeks after any dose change, then every 6 to 12 months once stable
Source: Synthroid (levothyroxine) prescribing information, section 2.4Diagnosis first
In 21 trials of 2,192 adults, treating mildly raised TSH did not improve symptoms, so a confirmed diagnosis matters
Source: Feller M, et al. JAMA 2018;320(13):1349-1359 (meta-analysis)Figures come from NIDDK, a professional guideline, the brand-name Synthroid label and a meta-analysis of randomized trials. Individual results vary, and your clinician sets your dose.
Your levothyroxine, dosed from your own TSH and free T4 and rechecked after every change, delivered to your door.
Clinician review of your labs and history
A US-licensed clinician reads TSH, free T4, symptoms and your current dose before prescribing.
Levothyroxine from a licensed US pharmacy
A 90-day supply of the 50 mcg tablet; your clinician sets the strength.
Free, discreet shipping
Ships 2 to 5 business days after approval.
Care team messaging
Ask about symptoms or dose changes any time; your clinician can adjust the plan.
Recheck guidance
TSH timing set by the label: 6 to 8 weeks after a change, then every 6 to 12 months once stable.
Results stored in your Vault
Every result stays in one place, so you can see TSH settle over time.
Free lab panel at month 3
Thyroid Check, as a progress check.
“I do not want another blood draw.”
Use the labs you already have
Upload recent results and your care team confirms whether they meet the requirement.
“What if my dose turns out to be wrong?”
Dose changes by message
Message your care team if something feels off and your clinician can adjust the plan.
Thyroid Check
Your thyroid makes T4, and your tissues convert it into active T3. When the gland cannot keep up, as in Hashimoto's thyroiditis or after thyroid surgery or radioactive iodine, energy, temperature and mood can all slow down.
Levothyroxine is the same T4 your thyroid would make. Taken every morning on an empty stomach, it tops up the missing hormone, and your clinician adjusts the dose using TSH and free T4 so you land in a steady range.
One tablet each morning, before breakfast. Take it on an empty stomach, 30 to 60 minutes before food. Your TSH is rechecked 6 to 8 weeks after any change.
Tell us about your hypothyroidism diagnosis and current dose, then upload recent TSH and free T4 results or book a draw near you.
About 10 minutes
They read your labs, symptoms and history together and prescribe only if levothyroxine fits.
Within 24 hours
If prescribed, your levothyroxine ships free in plain packaging, 2 to 5 business days after approval.
Message your care team any time. TSH is checked 6 to 8 weeks after any change until your dose is right.
Some people notice small changes early. The full effect of a dose builds more slowly, over about 4 to 6 weeks.
Your TSH is rechecked 6 to 8 weeks after any dose change, because that is when levels settle.
Checks move to every 6 to 12 months, or sooner if your health, weight or medicines change.
Pregnancy, a big weight change or a new medicine can change your dose. Tell your care team early.
Three things you can do alongside your treatment.
Hashimoto's thyroiditis, an autoimmune attack on the gland, is the most common cause of hypothyroidism. TPO and thyroglobulin antibodies show whether it is driving your levels, so your plan fits the cause.
Iodine and iron are needed to build thyroid hormone, and selenium and zinc help convert T4 into active T3. Food comes first; ask your clinician before adding supplements.
Chronic stress, poor sleep and ongoing inflammation are all linked with changes in thyroid hormone. A steady sleep schedule, regular movement and a stress outlet help your medication do its job.
| Feature | Levothyroxine (T4) | Adding liothyronine (T3) | Desiccated thyroid |
|---|---|---|---|
| What it is | Synthetic T4, which your body converts to active T3 | Synthetic T3, the active hormone, usually added to T4 | Dried animal thyroid containing both T4 and T3 |
| Where it sits in guidelines | The standard first treatment | An add-on for some people who still have symptoms | No consistently strong evidence that it beats levothyroxine |
| Dosing | One tablet each morning | Short acting, often split into two doses | Varies by product |
| Regulatory status | Approved by the FDA, with a boxed warning against use for weight loss | Approved by the FDA, with the same boxed warning | Marketed without FDA approval |
| Offered here | Yes, for people already diagnosed | Yes, as an add-on your clinician chooses | No |
Most people do well on levothyroxine alone. Your clinician decides whether anything else is worth adding.
Take 1 tablet by mouth every morning on empty stomach, 30-60 minutes before food; dose adjusted on TSH/Free T4 at 6-8 weeks
Thyroid hormone must not be used for weight loss. Doses larger than your body needs can be dangerous, especially alongside other weight loss medication.
Tell your care team straight away if you get chest pain, a pounding or racing or irregular heartbeat, shortness of breath, tremor or sweating or feeling overheated, or you lose weight without meaning to and cannot sleep.
Common side effects
Rare but serious
Do not take this if you have adrenal insufficiency that has not been treated first.
This is not a complete list of side effects. Message your care team about any symptom that worries you.
This page is for continuing treatment, so you need a diagnosis from a physician: hypothyroidism or Hashimoto's, or thyroid removal or radioactive iodine treatment. If you have symptoms but no diagnosis yet, get tested first and bring the results to a clinician.
Not on its own. Tiredness has many causes, including iron, sleep, mood and other hormones. A clinician looks at your symptoms alongside your labs, and if thyroid treatment is not the answer they can point you to what is.
No. The label carries a boxed warning against using thyroid hormone for weight loss, and doses above what your body needs can cause serious harm. Treatment replaces a hormone you are missing.
The right dose depends on your weight, age, heart health, other medicines and absorption, and it can shift with pregnancy or a large weight change. Small adjustments guided by TSH are a normal part of finding it.
Your clinician reads TSH against the standard lab range and against the tighter optimal ranges our clinicians use, together with free T4 and how you feel. The goal is the level where you feel well and your labs are steady.
For most people with an underactive thyroid, yes, because the gland is not recovering. Do not stop on your own. If your situation changes, your clinician can review whether you still need it.
90-day supply · $1.39/day · Billed $125 every 90 days
