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Sodium blood test (Na)

A sodium test measures blood sodium to assess hydration and electrolyte balance, with convenient Quest lab ordering and PocketMD guidance at Vitals Vault.

Kidney HealthIn every plan
Check your Sodium today

From $16.99 · Quest Diagnostics

  • No subscription
  • HSA/FSA eligible
  • Most results in 3–5 business days

Reference ranges

mmol/L
137142
135146
Optimal
137–142 mmol/L
Lab range
135–146 mmol/L
Ask AI for a summary

Sodium is one of the main electrolytes in your blood. It helps control how much water is inside and outside your cells, and it supports nerve signaling and muscle function.

A sodium blood test is usually ordered as part of a broader chemistry panel, so it often shows up on your results even if you did not specifically request it. When it is out of range, the “why” is often more important than the number itself.

Because sodium is tightly regulated by your kidneys and hormones, an abnormal result can point to dehydration or overhydration, medication effects, or a medical condition that changes how your body handles water and salt.

Do I need a Sodium test?

You may want a sodium test if you have symptoms that could reflect an electrolyte or fluid-balance problem, such as unusual fatigue, headaches, nausea, confusion, muscle cramps, weakness, or new swelling. More severe sodium shifts can contribute to dizziness, fainting, or changes in alertness, which should be evaluated urgently.

Testing is also common if you are managing a condition or situation that can shift sodium, including vomiting or diarrhea, heavy sweating, very high water intake, kidney disease, heart failure, liver disease, uncontrolled diabetes, or recent hospitalization. Your clinician may also monitor sodium if you take medications that affect water and salt handling, such as diuretics (“water pills”), certain antidepressants, anti-seizure medications, or desmopressin.

If you are comparing options, sodium is most useful when it is interpreted alongside related markers (especially potassium, chloride, bicarbonate/CO2, glucose, and kidney function). Your result can support clinician-directed care, but it is not a stand-alone diagnosis.

Sodium is measured on automated chemistry analyzers in CLIA-certified laboratories; results should be interpreted with your symptoms, medications, and companion labs rather than used for self-diagnosis.

Order labs to measure Sodium

from $16.99 at Quest Diagnostics.

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Get this test with Vitals Vault

If you want a clear, convenient way to check sodium, Vitals Vault lets you order lab testing directly and complete your blood draw at a Quest location. Sodium is typically included in common panels (like a BMP or CMP), which can be a better value than ordering it in isolation when you also want kidney function and other electrolytes.

After your results are in, you can use PocketMD to ask targeted questions such as what a mildly low sodium might mean for your specific medications, whether your pattern suggests dehydration versus water retention, and what follow-up tests are commonly paired with sodium.

If your sodium is meaningfully abnormal or you feel unwell, the next step is usually not “more sodium” or “less sodium” on your own. It is clarifying the cause and confirming the trend with repeat testing and related labs, ideally with clinician guidance.

  • Order online and draw at a Quest location
  • Results you can track over time in one place
  • PocketMD helps you prepare smarter follow-up questions

Key benefits of Sodium testing

  1. 01Helps assess hydration status and overall fluid balance when symptoms are nonspecific.
  2. 02Flags hyponatremia or hypernatremia early, which can affect brain and muscle function if severe.
  3. 03Adds context to dizziness, weakness, confusion, cramps, nausea, or unexplained fatigue.
  4. 04Supports medication monitoring, especially when you use diuretics or other drugs that shift water and salt handling.
  5. 05Pairs with kidney markers (BUN, creatinine, eGFR) to clarify whether the kidneys are contributing to the imbalance.
  6. 06Improves interpretation of acid–base and electrolyte patterns when reviewed with chloride and bicarbonate (CO2).
  7. 07Makes it easier to trend changes over time and decide when a repeat test is warranted.

What is Sodium?

Sodium (Na) is a mineral and electrolyte that circulates in your blood and body fluids. It is the main positively charged electrolyte outside your cells, so it strongly influences where water sits in your body.

Your body regulates sodium through a balance of thirst, kidney function, and hormones such as antidiuretic hormone (ADH/vasopressin), aldosterone, and natriuretic peptides. In many real-world cases, an “abnormal sodium” result is actually telling you about a water-balance problem (too much or too little body water) rather than a simple dietary salt issue.

Most labs report sodium as a concentration in blood (often called serum sodium). The number can shift quickly with acute illness, changes in fluid intake, IV fluids, or medication changes, so timing and context matter.

Sodium vs. salt intake

Dietary salt (sodium chloride) influences long-term health, especially blood pressure, but a single sodium blood level usually does not reflect how salty your diet is. Your kidneys and hormones keep blood sodium in a narrow range by adjusting water and sodium excretion.

Why sodium is often ordered with other labs

Sodium is most informative when you also see potassium, chloride, bicarbonate (CO2), glucose, and kidney function. Those results help distinguish dehydration from water retention, medication effects, kidney-related causes, and acid–base patterns.

What do my Sodium results mean?

Reference ranges

mmol/L
137142
135146
Optimal
137–142 mmol/L
Lab range
135–146 mmol/L

Low

Low sodium (hyponatremia)

Low sodium often means your body has relatively too much water compared with sodium, although true sodium loss can also occur. Common contributors include certain medications (especially diuretics and some antidepressants), vomiting/diarrhea with fluid replacement, hormonal signaling that causes water retention (such as SIADH), and advanced heart, liver, or kidney disease. Mild low sodium may cause few symptoms, but larger drops can lead to headache, confusion, unsteadiness, or worsening fatigue. Because rapid correction can be dangerous, persistent or symptomatic hyponatremia should be managed with clinician guidance rather than self-treatment.

Optimal

In-range sodium (typical balance)

An in-range sodium result usually suggests your kidneys and hormones are keeping water and electrolytes in balance at the time of testing. It does not rule out dehydration, overhydration, or illness entirely, but it makes a major sodium disturbance less likely. If you still have symptoms, your clinician may look at trends over time and at companion markers like potassium, chloride, bicarbonate (CO2), glucose, and kidney function to find a better explanation.

Clinical graph note: the optimal range is narrower than the standard lab range. Standard range: 135.00 - 146.00 mEq/L. Optimal range: 137.00 - 142.00 mEq/L.

High

High sodium (hypernatremia)

High sodium most often reflects a relative water deficit, meaning you have lost more water than sodium or you are not taking in enough fluids. This can happen with dehydration from fever, sweating, diarrhea, or inadequate access to water, and it can also occur with conditions that increase water loss (such as uncontrolled high blood sugar with frequent urination). Some cases relate to impaired thirst or hormonal regulation (for example, diabetes insipidus). Because significant hypernatremia can affect brain function, a high result—especially with symptoms like confusion or marked weakness—deserves prompt medical evaluation.

Factors that influence sodium results

Your sodium level can shift with recent fluid intake, IV fluids, vomiting/diarrhea, heavy exercise and sweating, and acute illness. Medications are a frequent driver, including diuretics, SSRIs/SNRIs, carbamazepine/oxcarbazepine, and desmopressin, among others. High blood glucose can lower measured sodium concentration (a dilution effect), so sodium is often interpreted alongside glucose. Lab handling issues are uncommon but possible, and repeating the test can help confirm an unexpected result.

What’s included

  • Sodium

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Frequently Asked Questions

What is a normal sodium level?

Most labs use a reference range around 135–145 mmol/L (mEq/L), but the exact range can vary by lab and method. Your best comparison is the range printed next to your result, plus your prior results if you have them.

Do I need to fast for a sodium blood test?

Fasting is not usually required for sodium by itself. However, sodium is commonly ordered in a BMP or CMP that includes glucose, and some clinicians prefer fasting for the most consistent glucose interpretation. Follow the collection instructions provided with your order.

Can drinking a lot of water lower sodium?

It can, especially if you drink large amounts quickly or if your body is already retaining water due to hormones, medications, or illness. Mild changes may be temporary, but persistent low sodium should be evaluated to identify the underlying cause.

Is low sodium caused by not eating enough salt?

Usually not. Blood sodium is regulated mainly by water balance and kidney/hormone control, so low sodium more often reflects too much body water relative to sodium, medication effects, or illness rather than low dietary salt intake.

What symptoms can high or low sodium cause?

Mild abnormalities may cause no symptoms. Larger shifts can cause headache, nausea, cramps, weakness, irritability, confusion, or trouble concentrating, and severe abnormalities can affect alertness and balance. If you have significant symptoms, seek medical care promptly.

How often should sodium be rechecked if it is abnormal?

That depends on how abnormal it is, whether you have symptoms, and what is suspected to be causing it. Mild, stable abnormalities may be rechecked in days to weeks, while more significant changes or medication adjustments may require faster follow-up. Your clinician can set the safest interval for your situation.

What other tests help interpret sodium?

Common companions include potassium, chloride, bicarbonate (CO2), glucose, BUN, creatinine, and eGFR. In specific situations, clinicians may add serum and urine osmolality, urine sodium, thyroid testing, or cortisol testing to clarify why sodium is off.

$16.99$24.98

Order sodium as part of a BMP or CMP so you can interpret it with the electrolytes and kidney markers that matter.

Order this test Browse biomarkers

Also included in

  • Essential (included)
  • Advanced (included)
  • Max (included)

On this page

  1. Introduction
  2. Do I need a Sodium test?
  3. Get this test with Vitals Vault
  4. Key benefits of Sodium testing
  5. What is Sodium?
  6. What do my Sodium results mean?
  7. What’s included
  8. Similar tests and related biomarkers
  9. Frequently Asked Questions

Get Sodium in a full panel.

Sodium is included in every plan. One draw at Quest, read against optimal ranges.

  • Essential

    Core Wellness

    $99one-time

    120+ biomarkers

    Includes Sodium

    • Check for deficiencies behind low energy and immunity
    • Catch heart basics before they become real issues
    • Find iron gaps that drive fatigue and brain fog
    Choose Essential
  • Advanced

    Hormones & Nutrients

    $199one-time

    140+ biomarkers

    Includes Sodium

    • Spot hidden heart risk with ApoB — missed by standard cholesterol panels
    • Uncover B12/folate gaps tied to fatigue, cognition, and methylation
    • Track hormone balance with estradiol and SHBG insights
    Choose Advanced
  • Max

    Most complete

    Longevity & Early Detection

    $399one-time

    160+ biomarkers

    Includes Sodium

    • Extended cardiovascular profiling (ApoA1, VLDL, LDH)
    • Bone density Z-scores & longevity markers (IGF-1, zinc)
    • Deep gut/liver/pancreas insights to protect longevity
    Choose Max
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