---
title: "Is Wellbutrin an SSRI? Zoloft vs Bupropion"
description: "Is Wellbutrin an SSRI? No. It is bupropion, an NDRI. Compare Zoloft vs bupropion for depression, including uses, key risks, and access."
canonical: "https://www.vitalsvault.com/treatment-learn/zoloft-vs-wellbutrin-depression"
last-updated: 2026-08-22
---

# Is Wellbutrin an SSRI? Zoloft vs Bupropion

> Is Wellbutrin an SSRI? No. It is bupropion, an NDRI. Compare Zoloft vs bupropion for depression, including uses, key risks, and access.

---

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