---
title: "How long can Zepbound be unrefrigerated?"
description: "How long can Zepbound be unrefrigerated? Up to 21 days at 86°F (30°C) or below. If it gets hotter, freezes, or exceeds 21 days, do not use it."
canonical: "https://www.vitalsvault.com/treatment-learn/how-long-can-zepbound-be-unrefrigerated"
last-updated: 2026-08-22
---

# How long can Zepbound be unrefrigerated?

> How long can Zepbound be unrefrigerated? Up to 21 days at 86°F (30°C) or below. If it gets hotter, freezes, or exceeds 21 days, do not use it.

---

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